Benefits in Cardiac Function from a Remote Exercise Program in Children with Obesity.
Savina MannarinoSara SantacesariaIrene RasoMassimo GarbinAndreana PipoloSilvia GhigliaGabriele TaralloAnnalisa De SilvestriNicola LovecchioDaniela LuciniVittoria Carnevale PellinoGiuseppina BernardelliAlessandro GattiVirginia RossiValeria CalcaterraGian Vincenzo ZuccottiPublished in: International journal of environmental research and public health (2023)
Physical activity (PA) is a crucial factor in preventing and treating obesity and related complications. In this one-arm pre-post longitudinal prospective study, we evaluated the effects of a 12-week online supervised training program on cardiac morphology, function and blood pressure (BP) in children with obesity. The training program consisted of three sessions per week, each lasting 60 min. Advanced echocardiographic imaging (tissue Doppler and longitudinal strain analysis) was used to detect subclinical changes in heart function. Categorical variables were described as counts and percentages; quantitative variables as the mean and standard deviation (SD) as they were normally distributed (Shapiro-Wilks test). Pre-post comparisons were made with a paired t -test. A total of 27/38 (71%) enrolled patients (18M/9F, 11 ± 2 years) completed the training protocol and were considered in the analysis. At baseline, no hypertensive patient was noted; all echocardiographic variables were within the normal range. After training, we observed a significant reduction in BP parameters, including systolic BP values and Z-score, diastolic BP values, centiles and Z-score, and mean arterial pressure (all p < 0.05). Significant variations in echocardiographic interventricular septum (IVSd) thickness ( p = 0.011), IVSd Z-score ( p = 0.001), left ventricular (LV) end-diastolic diameter ( p = 0.045), LV posterior wall thickness Z-score ( p = 0.017), and LV global longitudinal strain ( p = 0.016) were detected. No differences in LV diastolic function and right ventricular strain were noted. PA plays a decisive role in improving BP control and has benefits on left ventricle systolic function, representing a strategic approach to limit CV risk. Online exercise could be an excellent method of training in children with obesity.
Keyphrases
- left ventricular
- blood pressure
- cardiac resynchronization therapy
- insulin resistance
- heart failure
- metabolic syndrome
- ejection fraction
- mitral valve
- physical activity
- hypertrophic cardiomyopathy
- weight loss
- left atrial
- aortic stenosis
- acute myocardial infarction
- type diabetes
- high fat diet induced
- weight gain
- young adults
- end stage renal disease
- high resolution
- cross sectional
- machine learning
- social media
- hypertensive patients
- randomized controlled trial
- high intensity
- body mass index
- skeletal muscle
- clinical trial
- adipose tissue
- optical coherence tomography
- coronary artery
- virtual reality
- blood glucose
- heart rate
- peritoneal dialysis
- resistance training
- quality improvement
- blood flow
- study protocol
- drug induced
- peripheral blood
- glycemic control
- body composition