ANGPTL4 Suppresses Clear Cell Renal Cell Carcinoma via Inhibition of Lysosomal Acid Lipase.

Zeng Jin Umasankar De Tanzia Islam Tithi Jeremy Kleberg Akhila Nataraj Elena Jolley Madison E Carelock Brandon S J Davies Weizhou Zhang Ryan Kolb

Published in: Cancer research communications (2024)

Our data indicate angiopoietin-like 4 (ANGPTL4) acts as a tumor suppressor in clear cell renal cell carcinoma via regulating lipid metabolism and identifies a cohort of patients with lower expression of ANGPTL4 that are correlated with shorter survival.

Keyphrases

poor prognosis
signaling pathway
electronic health record
big data
binding protein
free survival
gene expression
fatty acid
long non coding rna
data analysis
artificial intelligence