A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice.

Rogier L C PlasMieke PolandJoyce FaberJosep ArgilèsMiriam van DijkAlessandro LavianoJocelijn MeijerinkRenger F Witkamp Ardy van HelvoortKlaske van Norren

Published in: International journal of molecular sciences (2019)

Our results suggest that cancer-related hypercalcemia may be ameliorated by a nutritional intervention rich in leucine and fish oil. The effect of fish oil possibly relates to a DHA-induced reduction of PTHrP excretion by the tumour.

Keyphrases

fatty acid
high glucose
randomized controlled trial
physical activity
mouse model
metabolic syndrome
adipose tissue
skeletal muscle
insulin resistance