Human Tumor-Associated Macrophages and Neutrophils Regulate Antitumor Antibody Efficacy through Lethal and Sublethal Trogocytosis.
Sunil SinghalAbhishek S RaoJason E StadanlickKyle BrunsNeil T SullivanAndres BermudezAdam Honig-FrandRyan KrouseSachinthani ArambepolaEmily GuoEdmund K MoonGeorge GeorgiouThomas ValeriusSteven M AlbeldaEvgeniy B EruslanovPublished in: Cancer research (2024)
The elucidation of the conditions and mechanisms by which human FcR+ myeloid effectors mediate cancer cell resistance and killing during antibody treatment could help develop improved strategies for treating solid tumors.