Thomas Valerius (T Valerius)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 23

Top Topics

Allogeneic Hematopoietic Stem Cell Transplantation

Tyrosine Kinase

Stem Cell Transplantation

Anti Inflammatory

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Nature communications

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Chilam Chan, J H Marco Jansen, Ilona S T Hendriks, Ida C van der Peet, Meggy E L Verdonschot, Elsemieke M Passchier, Maria Tsioumpekou, Maaike Nederend, Sharon A Klomp, Matthias Peipp, Thomas Valerius, Jeanette H W Leusen, Patricia A Olofsen
Enhancing neutrophil cytotoxicity of a panel of clinical EGFR antibodies by Fc engineering to IgA3.0. Molecular cancer therapeutics (2024)
Sunil Singhal, Abhishek S Rao, Jason E Stadanlick, Kyle Bruns, Neil T Sullivan, Andres Bermudez, Adam Honig-Frand, Ryan Krouse, Sachinthani Arambepola, Emily Guo, Edmund K Moon, George Georgiou, Thomas Valerius, Steven M Albelda, Evgeniy B Eruslanov
Human Tumor-Associated Macrophages and Neutrophils Regulate Antitumor Antibody Efficacy through Lethal and Sublethal Trogocytosis. Cancer research 84 (7) (2024)
Stian Foss, Siri Aastedatter Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz, Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg, Simone Mester, Malin Bern, Mitchell Evers, Diane B Bratlie, Terje E Michaelsen, Tilman Schlothauer, Devin Sok, Jayanta Bhattacharya, Jeanette Leusen, Thomas Valerius, Sanjay Ram, Suzan H M Rooijakkers, Inger Sandlie, Jan Terje Andersen
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria. Nature communications 15 (1) (2024)
Stian Foss, Siri Aastedatter Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz, Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg, Simone Mester, Malin Bern, Mitchell Evers, Diane B Bratlie, Terje E Michaelsen, Tilman Schlothauer, Devin Sok, Jayanta Bhattacharya, Jeanette Leusen, Thomas Valerius, Sanjay Ram, Suzan H M Rooijakkers, Inger Sandlie, Jan Terje Andersen
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria. Nature communications 15 (1) (2024)
Stian Foss, Siri Aastedatter Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz, Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg, Simone Mester, Malin Bern, Mitchell Evers, Diane B Bratlie, Terje E Michaelsen, Tilman Schlothauer, Devin Sok, Jayanta Bhattacharya, Jeanette Leusen, Thomas Valerius, Sanjay Ram, Suzan H M Rooijakkers, Inger Sandlie, Jan Terje Andersen
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria. Nature communications 15 (1) (2024)
Stian Foss, Siri Aastedatter Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz, Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg, Simone Mester, Malin Bern, Mitchell Evers, Diane B Bratlie, Terje E Michaelsen, Tilman Schlothauer, Devin Sok, Jayanta Bhattacharya, Jeanette Leusen, Thomas Valerius, Sanjay Ram, Suzan H M Rooijakkers, Inger Sandlie, Jan Terje Andersen
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria. Nature communications 15 (1) (2024)
Sunil Singhal, Abhishek S Rao, Jason E Stadanlick, Kyle Bruns, Neil T Sullivan, Andres Bermudez, Adam Honig-Frand, Ryan Krouse, Sachinthani Arambepola, Emily Guo, Edmund K Moon, George Georgiou, Thomas Valerius, Steven M Albelda, Evgeniy B Eruslanov
Human tumor-associated macrophages and neutrophils regulate anti-tumor antibody efficacy through lethal and sublethal trogocytosis. Cancer research (2024)
Sunil Singhal, Abhishek S Rao, Jason E Stadanlick, Kyle Bruns, Neil T Sullivan, Andres Bermudez, Adam Honig-Frand, Ryan Krouse, Sachinthani Arambepola, Emily Guo, Edmund K Moon, George Georgiou, Thomas Valerius, Steven M Albelda, Evgeniy B Eruslanov
Human Tumor-Associated Macrophages and Neutrophils Regulate Antitumor Antibody Efficacy through Lethal and Sublethal Trogocytosis. Cancer research 84 (7) (2024)
Marjolein C Stip, Mitchell Evers, Maaike Nederend, Chilam Chan, Karli R Reiding, Mirjam J Damen, Albert J R Heck, Sofia Koustoulidou, Ruud Ramakers, Gerard C Krijger, Remmert de Roos, Edouard Souteyrand, Annelisa M Cornel, Miranda P Dierselhuis, Marco Jansen, Mark de Boer, Thomas Valerius, Geert van Tetering, Jeanette H W Leusen, Friederike Meyer-Wentrup
IgA antibody immunotherapy targeting GD2 is effective in preclinical neuroblastoma models. Journal for immunotherapy of cancer 11 (7) (2023)
Dennis Vestergaard Pedersen, Heidi Gytz, Mikael B L Winkler, Alessandra Zarantonello, Niklas Baumann, Annette G Hansen, Steffen Thiel, Gregers Rom Andersen, Thomas Valerius, Nick Stub Laursen
Bispecific Complement Engagers for Targeted Complement Activation. Journal of immunology (Baltimore, Md. : 1950) (2023)
Jesus Duque-Afonso, Juergen Finke, Maud Ngoya, Jacques-Emmanuel Galimard, Charles F Craddock, Kavita Raj, Adrian Bloor, Emma Nicholson, Matthias Eder, Orchard Kim, Thomas Valerius, John A Snowden, Eleni Tholouli, Charles Crawley, Matthew Collin, Keith M O Wilson, Alain Gadisseur, Rachel Protheroe, Eva Maria Wagner-Drouet, Bipin P Savani, Alexandros Spirydonidis, Fabio Ciceri, Arnon Nagler, Florent Malard
Comparison of fludarabine/melphalan (FluMel) with fludarabine/melphalan/BCNU or thiotepa (FBM/FTM) in patients with AML in first complete remission undergoing allogeneic hematopoietic stem cell transplantation - a registry study on behalf of the EBMT Acute Leukemia Working Party. Bone marrow transplantation (2023)
M Chernyavska, M Masoudnia, Thomas Valerius, Wouter P R Verdurmen
Organ-on-a-chip models for development of cancer immunotherapies. Cancer immunology, immunotherapy : CII (2023)
Chilam Chan, Marta Lustig, J H Marco Jansen, Laura Garcia Villagrasa, Leon Raymakers, Lois A Daamen, Thomas Valerius, Geert van Tetering, Jeanette H W Leusen
Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9. Cancers 15 (13) (2023)
Mitchell Evers, Marjolein Stip, Kaylee Keller, Hanneke Willemen, Maaike Nederend, Marco Jansen, Chilam Chan, Kevin Budding, Stefan Nierkens, Thomas Valerius, Friederike Meyer-Wentrup, Niels Eijkelkamp, Jeanette H W Leusen
Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma. Journal for immunotherapy of cancer 9 (10) (2022)
Kristina Müller, Fotini Vogiatzi, Dorothee Winterberg, Thies Rösner, Lennart Lenk, Lorenz Bastian, Carina L Gehlert, Marie-Pauline Autenrieb, Monika Brüggemann, Gunnar Cario, Martin Schrappe, Andreas E Kulozik, Cornelia Eckert, Anke K Bergmann, Beat Bornhauser, Jean-Pierre Bourquin, Thomas Valerius, Matthias Peipp, Christian Kellner, Denis M Schewe
Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL. Blood 140 (1) (2022)
Fotini Vogiatzi, Julia Heymann, Kristina Müller, Dorothee Winterberg, Aneta Drakul, Thies Rösner, Lennart Lenk, Michelle Heib, Carina Lynn Gehlert, Gunnar Cario, Martin Schrappe, Alexander Claviez, Beat Bornhauser, Jean-Pierre Bourquin, Simon Bomken, Dieter Adam, Fabian-Simon Frielitz, Brtitta Maecker-Kolhoff, Martin Stanulla, Thomas Valerius, Matthias Peipp, Christian Kellner, Denis M Schewe
Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis. Blood advances 6 (16) (2022)
Dorothee Winterberg, Lennart Lenk, Maren Oßwald, Fotini Vogiatzi, Carina Lynn Gehlert, Fabian-Simon Frielitz, Katja Klausz, Thies Rösner, Thomas Valerius, Anna Trauzold, Matthias Peipp, Christian Kellner, Denis Martin Schewe
Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo. Journal of clinical medicine 10 (12) (2021)
Mitchell Evers, Thies Rösner, Anna Dünkel, J H Marco Jansen, Niklas Baumann, Toine Ten Broeke, Maaike Nederend, Klara Eichholz, Katja Klausz, Karli Reiding, Denis M Schewe, Christian Kellner, Matthias Peipp, Jeanette H W Leusen, Thomas Valerius
The selection of variable regions affects effector mechanisms of IgA antibodies against CD20. Blood advances 5 (19) (2021)
Joseph Tintelnot, Natalie Baum, Christoph Schultheiß, Friederike Braig, Marie Trentmann, Johannes Finter, William Fumey, Peter Bannas, Boris Fehse, Kristoffer Riecken, Kerstin Schuetze, Carsten Bokemeyer, Thies Rösner, Thomas Valerius, Matthias Peipp, Friedrich Koch-Nolte, Mascha Binder
Nanobody Targeting of Epidermal Growth Factor Receptor (EGFR) Ectodomain Variants Overcomes Resistance to Therapeutic EGFR Antibodies. Molecular cancer therapeutics 18 (4) (2019)
Patrick J Engelberts, Esther C W Breij, Thomas Valerius, Janine Schuurman, Paul W H I Parren, Frank J Beurskens
Response to Comment on "Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells". Journal of immunology (Baltimore, Md. : 1950) 200 (8) (2019)
Louise W Treffers, Toine Ten Broeke, Thies Rösner, J H Marco Jansen, Michel van Houdt, Steffen Kahle, Karin Schornagel, Paul J J H Verkuijlen, Jan M Prins, Katka Franke, Taco W Kuijpers, Timo K van den Berg, Thomas Valerius, Jeanette H W Leusen, Hanke L Matlung
IgA-Mediated Killing of Tumor Cells by Neutrophils Is Enhanced by CD47-SIRPα Checkpoint Inhibition. Cancer immunology research 8 (1) (2019)
Annalina Tammen, Stefanie Derer, Ralf Schwanbeck, Thies Rösner, Anna Kretschmer, Frank J Beurskens, Janine Schuurman, Paul W H I Parren, Thomas Valerius
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells. Journal of immunology (Baltimore, Md. : 1950) 198 (4) (2017)
Patrick J Engelberts, Marleen Voorhorst, Janine Schuurman, Tom van Meerten, Joost M Bakker, Tom Vink, Wendy J M Mackus, Esther C W Breij, Stefanie Derer, Thomas Valerius, Jan G J van de Winkel, Paul W H I Parren, Frank J Beurskens
Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells. Journal of immunology (Baltimore, Md. : 1950) 197 (12) (2016)
Stefanie Derer, Michael Cossham, Thies Rösner, Christian Kellner, Frank J Beurskens, Ralf Schwanbeck, Stefan Lohse, Christian Sina, Matthias Peipp, Thomas Valerius
A Complement-Optimized EGFR Antibody Improves Cytotoxic Functions of Polymorphonuclear Cells against Tumor Cells. Journal of immunology (Baltimore, Md. : 1950) 195 (10) (2015)