The effect of photobiomodulation therapy in common maxillofacial injuries: Current status.
Mostafa AlamShahryar KaramiMeysam MohammadikhahAshkan BadkoobehMohsen GolkarKamyar AbbasiReza Sayyad SoufdoostLotfollah Kamali HakimSahar TalebiReza Abdollahi NamanlooAhmed HussainArtak HeboyanHamid TebyanianPublished in: Cell biochemistry and function (2024)
The use of photobiomodulation therapy (PBMT) may be used for treating trauma to the maxillofacial region. The effects of PBMT on maxillofacial injuries were discussed in this review article. The electronic databases Pubmed, Scopus, and Web of Science were thoroughly searched. This review included in vitro, in vivo, and clinical studies describing how PBMT can be used in maxillofacial tissue engineering and regenerative medicine. Some studies suggest that PBMT may offer a promising therapy for traumatic maxillofacial injuries because it can stimulate the differentiation and proliferation of various cells, including dental pulp cells and mesenchymal stem cells, enhancing bone regeneration and osseointegration. PBMT reduces pain and swelling after oral surgery and tooth extraction in human and animal models of maxillofacial injuries. Patients with temporomandibular disorders also benefit from PBMT in terms of reduced inflammation and symptoms. PBMT still has some limitations, such as the need for standardizing parameters. PBMT must also be evaluated further in randomized controlled trials in various maxillofacial injuries. As a result, PBMT offers a safe and noninvasive treatment option for patients suffering from traumatic maxillofacial injuries. PBMT still requires further research to establish its efficacy in clinical practice and determine the optimal parameters.
Keyphrases
- mesenchymal stem cells
- induced apoptosis
- spinal cord injury
- randomized controlled trial
- end stage renal disease
- clinical practice
- bone regeneration
- chronic kidney disease
- cell cycle arrest
- signaling pathway
- public health
- minimally invasive
- machine learning
- newly diagnosed
- depressive symptoms
- pain management
- coronary artery disease
- big data
- clinical trial
- percutaneous coronary intervention
- artificial intelligence
- replacement therapy
- pluripotent stem cells