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Molecular features of glioblastomas in long-term survivors compared to short-term survivors-a matched-pair analysis.

Vivien N SommerlathDaniel BuergyNima EtminanStefanie BrehmerDavid ReussGustavo R SarriaMarie-Christin GuiotDaniel HänggiFrederik WenzKevin PetreccaFrank Anton Giordano
Published in: Radiation oncology (London, England) (2022)
In this retrospective analysis, GFAP expression and MGMT promoter methylation were associated with LTS. Given the hypothesis-generating nature of our study, these observations should be confirmed in prospective clinical trials.
Keyphrases
  • clinical trial
  • dna methylation
  • young adults
  • poor prognosis
  • gene expression
  • transcription factor
  • genome wide
  • randomized controlled trial
  • single molecule
  • study protocol