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Metabolic Signatures of Genetically Elevated Vitamin D Among Chinese: Observational and Mendelian Randomization Study.

Zhenhuang ZhuangCanqing YuYu GuoZheng BianLing YangIona Y MillwoodRobin G WaltersYiping ChenQinai XuMingyuan ZouJunshi ChenZhengming ChenJun LvTao HuangLiming Li
Published in: The Journal of clinical endocrinology and metabolism (2021)
The MR analysis of metabolic data based a population-based cohort suggested a potential causal association of plasma 25(OH)D with cholesterol, lipoprotein particle, phospholipid concentrations, and total lipids within very small VLDL and IDL. Our findings highlight a long-term effect of 25(OH)D levels in maintaining healthy lipid metabolism.
Keyphrases
  • fatty acid
  • low density lipoprotein
  • magnetic resonance
  • electronic health record
  • big data
  • machine learning
  • cross sectional
  • contrast enhanced
  • dna methylation
  • deep learning
  • data analysis
  • artificial intelligence