Impact of intratumoral microbiome on tumor immunity and prognosis in human pancreatic ductal adenocarcinoma.

Shohei AbeAtsuhiro MasudaTomonori MatsumotoJun InoueHirochika ToyamaArata SakaiTakashi KobayashiTakeshi TanakaMasahiro TsujimaeKohei YamakawaMasanori GondaShigeto MasudaHisahiro UemuraShinya KohashiNoriko InomataKae NagaoYoshiyuki HaradaMika MikiYosuke IrieNoriko JuriTestuhisa KoYusuke YokotaniYuki OkaShogo OtaMaki KanzawaTomoo ItohToshio ImaiTakumi FukumotoEiji HaraYuzo Kodama

Published in: Journal of gastroenterology (2024)

Intratumoral infection of anaerobic bacteria such as Bacteroides, Lactobacillus, and Peptoniphilus is correlated with the suppressed anti-PDAC immunity and poor prognosis.

Keyphrases

poor prognosis
long non coding rna
endothelial cells
microbial community
wastewater treatment
induced pluripotent stem cells
pluripotent stem cells