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Hepatic Mac2-BP expression depends on liver fibrosis and inflammation due to fat accumulation in patients with metabolic dysfunction-associated steatotic liver disease.

Haruki UojimaHanako TsujikawaKen YamazakiMasaya SugiyamaAkira TakeYoshihiko SakaguchiKazuyoshi GotohTakashi SatohHisashi HidakaShunji HayashiChika KusanoMichiie SakamotoMasashi Mizokami
Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)
Fat accumulation in patients with MASLD leads to M2BP expression in hepatocytes due to liver inflammation and that in sinusoidal cells due to fibrosis.
Keyphrases
  • liver fibrosis
  • oxidative stress
  • poor prognosis
  • induced apoptosis
  • adipose tissue
  • fatty acid
  • cell cycle arrest
  • long non coding rna
  • liver injury
  • drug induced