Serum Free Fatty Acid Changes Caused by High Expression of Stearoyl-CoA Desaturase 1 in Tumor Tissues Are Early Diagnostic Markers for Ovarian Cancer.

Kanoko Katoh Yuki Katoh Akiko Kubo Miho Iida Yuji Ikeda Takashi Iwata Hiroshi Nishio Masaki Sugawara Daiki Kato Makoto Suematsu Shuichi Hirai Kei Kawana

Published in: Cancer research communications (2023)

Measurement of serum FFA levels by changes in the expression of fatty acid metabolizing enzymes in tumor tissue would allow early detection of ovarian cancer. In particular, the SCD1-associated FFAs, oleic and arachidic acid, would be powerful new screening tools for early-stage ovarian cancer.

Keyphrases

fatty acid
early stage
poor prognosis
gene expression
binding protein
long non coding rna
squamous cell carcinoma