Therapeutic efficacy of tranexamic acid on traumatic brain injury: a systematic review and meta-analysis.
Jia-Xing SongJian-Xiang WuHai ZhongWei ChenJian-Chun ZhengPublished in: Scandinavian journal of trauma, resuscitation and emergency medicine (2024)
The administration of TXA is significantly associated with reduced mortality and hemorrhage growth in patients suffering from TBI, while the need of neurosurgery, seizures, and incidence of pulmonary embolism remains comparable to that observed with placebo.
Keyphrases
- pulmonary embolism
- traumatic brain injury
- end stage renal disease
- inferior vena cava
- newly diagnosed
- ejection fraction
- risk factors
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- clinical trial
- randomized controlled trial
- severe traumatic brain injury
- patient reported
- mild traumatic brain injury
- placebo controlled