Gait and Conditioned Fear Impairments in a Mouse Model of Comorbid TBI and PTSD.
Peyton Teutsch WickhamCarolyn E Jones-TinsleyMara E KaiserNatasha Avalon GardnerMiranda M LimPublished in: Behavioural neurology (2018)
These results indicate that SPS paired with CCI in mice produces unique behavioral impairments in gait and fear recall that are not present in either condition alone. Further studies are underway to examine additional behavioral, physiological, and pathological phenotypes in this combined model of TBI + PTSD.
Keyphrases
- traumatic brain injury
- mouse model
- posttraumatic stress disorder
- severe traumatic brain injury
- social support
- cerebral palsy
- mild traumatic brain injury
- neuropathic pain
- prefrontal cortex
- high fat diet induced
- type diabetes
- case control
- depressive symptoms
- spinal cord
- insulin resistance
- adipose tissue
- metabolic syndrome