Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Zhihan ZhaoHuan LanIbrahim El-BattrawyXin LiFanis BuljubasicKatherine SattlerGökhan YücelSiegfried LangMalte TiburcyWolfram-Hubertus ZimmermannLukas CyganekJochen Sven UtikalThomas WielandMartin Borggrefe Xiao-Bo ZhouIbrahim Akin

Published in: Stem cells international (2018)

Our data demonstrate that most ion channels, which are present in healthy or diseased cardiomyocytes, exist in hiPSC-CMs. Some of them contribute to action potential performance and are regulated by adrenergic stimulation.

Keyphrases

high glucose
endothelial cells
poor prognosis
diabetic rats
induced pluripotent stem cells
big data
pluripotent stem cells
human health
binding protein
machine learning
risk assessment
climate change