Abnormal N-Glycosylation of Human Lens Epithelial Cells in Type-2 Diabetes May Contribute to Cataract Progression.
Ivan Ramos-MartínezOscar Vivanco-RojasBrenda Juárez-DomínguezLuis Hernández-ZimbrónLenin Ochoa-de la PazHugo Quiroz-MercadoEleazar Ramírez HernándezRosario Gulias-CañizoEdgar ZentenoPublished in: Clinical ophthalmology (Auckland, N.Z.) (2021)
These results suggest that over-expression of N-glycosidically linked human type 1 cytokeratin may induce capsule disruption and affect selective permeability, allowing the entry of different molecules to the lens that facilitate cataract progression.