Cheonggukjang-Specific Component 1,3-Diphenyl-2-Propanone as a Novel PPARα/γ Dual Agonist: An In Vitro and In Silico Study.

Radha ArulkumarHee-Jin JungSang-Gyun NohDaeui Park Hae Young Chung

Published in: International journal of molecular sciences (2021)

The Cheonggukjang-specific compound DPP could be a novel PPARα/γ dual agonist and it is warranted to determine the therapeutic potential of PPARα/γ activation by dietary intervention and/or supplementation in the treatment of metabolic disorders without causing any adverse effects.

Keyphrases

insulin resistance
randomized controlled trial
fatty acid
molecular docking
metabolic syndrome
combination therapy
replacement therapy
molecular dynamics simulations