Directed differentiation of human pluripotent stem cells into epidermal stem and progenitor cells.
Sonya Ruiz-TorresPaul F LambertKathryn A Wikenheiser-BrokampSusanne I WellsPublished in: Molecular biology reports (2021)
This protocol provides an accelerated path for the generation of human ESPCs and 3D epidermal models to study normal epidermal development and homeostasis, elucidate mechanisms of epidermal disease pathogenesis, and provides a platform for developing personalized therapies.