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Joint longitudinal and time-to-event modelling compared with standard Cox modelling in patients with type 2 diabetes with and without established cardiovascular disease: An analysis of the EXSCEL trial.

Abderrahim OulhajFaisal AzizAbubaker SulimanNayyar IqbalRuth L ColemanRury R HolmanHarald Sourij
Published in: Diabetes, obesity & metabolism (2023)
The analysis demonstrates that the joint modelling approach, considering trajectories of cardiovascular risk factors, provides superior predictive performance compared to standard RPTs that use only a single timepoint.
Keyphrases
  • cardiovascular risk factors
  • cardiovascular disease
  • metabolic syndrome
  • clinical trial
  • depressive symptoms
  • study protocol
  • randomized controlled trial
  • cross sectional
  • cardiovascular events