Longitudinal change in autonomic symptoms predicts activities of daily living and depression in Parkinson's disease.

Miriam SklerovChia-Hao ShihNina BrownerJose-Alberto PalmaMartin StynerEran Dayan

Published in: Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2020)

Longitudinal changes in autonomic symptoms impact ADLs function in patients with early signs of PD, both directly and indirectly through their impact on depressive symptoms. Future investigation into the influence of treatment of these symptoms on outcomes in PD is warranted.

Keyphrases

depressive symptoms
sleep quality
heart rate variability
heart rate
cross sectional
social support
type diabetes
current status
metabolic syndrome
adipose tissue
combination therapy
weight loss
glycemic control