Clinical variables associated with immune checkpoint inhibitor outcomes in patients with metastatic urothelial carcinoma: a multicentre retrospective cohort study.

Soumaya LabidiNicholas MetiReeta BaruaMengqi LiJamila RiromarDi Maria JiangNazanin Fallah-RadSrikala S SridharSonia V Del RinconRossanna C PezoCristiano FerrarioSusanna ChengAdrian G SacherApril A N Rose

Published in: BMJ open (2024)

Our data identified BMI and bone metastases as novel clinical biomarkers that were independently associated with ICI outcomes in mUC. External and prospective validation are warranted.

Keyphrases

body mass index
clinical trial
electronic health record
study protocol
randomized controlled trial
type diabetes
metabolic syndrome
cross sectional
physical activity
machine learning
adipose tissue
skeletal muscle
deep learning
data analysis
glycemic control