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Investigation of allele-specific expression of genes involved in adipogenesis and lipid metabolism suggests complex regulatory mechanisms of PPARGC1A expression in porcine fat tissues.

Monika StachowiakIzabela SzczerbalKrzysztof Flisikowski
Published in: BMC genetics (2018)
Our analysis of differential allelic expression suggests that PPARGC1A is subjected to cis-regulation in porcine fat tissues. Further studies are necessary to identify other regulatory elements localized outside the PPARGC1A proximal promoter region.
Keyphrases
  • poor prognosis
  • gene expression
  • transcription factor
  • adipose tissue
  • binding protein
  • fatty acid
  • dna methylation
  • long non coding rna
  • type diabetes
  • metabolic syndrome
  • case control