Current status of therapeutic approaches and vaccines for SARS-CoV-2.
Braira WahidAnam AmirAyesha AmeenMuhammad IdreesPublished in: Future microbiology (2021)
SARS-CoV-2, declared a pandemic in March 2020, is the current global health challenge. The global bioburden of this virus is increasing at a rapid pace. Many antiviral drugs and vaccines have been registered for clinical trials because of their inhibitory activity observed in vitro. Currently, five types of vaccines have successfully passed Phase IV clinical trial and are being administered in populations worldwide. A plethora of experimental designs have been proposed worldwide in order to find a safe and efficacious treatment option. Therefore, it is necessary to provide baseline data and information to clinicians and researchers so that they can review the current status of therapeutics and efficacy of already developed vaccines. This review article summarizes all therapeutic options that may help to combat SARS-CoV-2.
Keyphrases
- sars cov
- clinical trial
- current status
- global health
- respiratory syndrome coronavirus
- public health
- phase ii
- open label
- randomized controlled trial
- small molecule
- electronic health record
- double blind
- big data
- study protocol
- coronavirus disease
- social media
- health information
- artificial intelligence
- deep learning
- data analysis