In-depth characterization of a mouse model of postoperative atrial fibrillation.
Joshua A KeefeJosé Alberto Navarro-GarcíaLi NiSvetlana ReillyDobromir DobrevXander H T WehrensPublished in: The journal of cardiovascular aging (2022)
Here, we demonstrate that the increased POAF risk associated with CT surgery is most pronounced in female and 12-19-week-old mice, and that the expression of inflammatory cytokines is upregulated in the atria of THOR mice prone to inducible AF.
Keyphrases
- atrial fibrillation
- mouse model
- high fat diet induced
- minimally invasive
- poor prognosis
- computed tomography
- patients undergoing
- left atrial
- coronary artery bypass
- oral anticoagulants
- catheter ablation
- magnetic resonance imaging
- contrast enhanced
- type diabetes
- image quality
- metabolic syndrome
- acute coronary syndrome
- clinical trial
- skeletal muscle
- insulin resistance
- magnetic resonance
- venous thromboembolism