Xander H T Wehrens (Xander Ht Wehrens)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 61

Top Topics

Atrial Fibrillation

Catheter Ablation

Top Venues

Circulation. Arrhythmia and electrophysiology

Circulation research

The Journal of general physiology

Cardiovascular research

This page only lists publications with an associated author ORCID identifier.

Publications

Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y Abdelnasser, M David Stewart, Satadru K Lahiri, Xander H T Wehrens, Bradley K McConnell
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. Circulation research (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
José Alberto Navarro-García, Florian Bruns, Oliver M Moore, Marcel A Tekook, Dobromir Dobrev, Christina Y Miyake, Xander H T Wehrens
In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates. Current protocols 4 (2) (2024)
Joshua A Keefe, Xander H T Wehrens
Blocking p38γ/δ, a molecular cardiac defibrillator. Nature cardiovascular research 2 (12) (2024)
Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y Abdelnasser, M David Stewart, Satadru K Lahiri, Xander H T Wehrens, Bradley K McConnell
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. Circulation research 134 (8) (2024)
Joshua A Keefe, Shuai Zhao, Xander H T Wehrens
A mechanistic LNK between inflammation and atrial fibrillation? Cardiovascular research 120 (8) (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
José Alberto Navarro-García, Florian Bruns, Oliver M Moore, Marcel A Tekook, Dobromir Dobrev, Christina Y Miyake, Xander H T Wehrens
In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates. Current protocols 4 (2) (2024)
Sasha Z Prisco, Lynn M Hartweck, Felipe Kazmirczak, Jenna B Mendelson, Stephanie L Deng, Madelyn J Blake, Satadru K Lahiri, Xander H T Wehrens, Kurt W Prins
Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation 150 (8) (2024)
Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y Abdelnasser, M David Stewart, Satadru K Lahiri, Xander H T Wehrens, Bradley K McConnell
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. Circulation research 134 (8) (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
Satadru K Lahiri, Feng Jin, Yue Zhou, Ann P Quick, Carlos F Kramm, Meng C Wang, Xander H T Wehrens
Altered myocardial lipid regulation in junctophilin-2-associated familial cardiomyopathies. Life science alliance 7 (5) (2024)
Shuai Zhao, Xander H T Wehrens
Pathways to precision medicine: deciphering the secrets of physiological and pathological atrial enlargement. Clinical science (London, England : 1979) 138 (18) (2024)
José Alberto Navarro-García, Florian Bruns, Oliver M Moore, Marcel A Tekook, Dobromir Dobrev, Christina Y Miyake, Xander H T Wehrens
In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates. Current protocols 4 (2) (2024)
Sasha Z Prisco, Lynn M Hartweck, Felipe Kazmirczak, Jenna B Mendelson, Stephanie L Deng, Madelyn J Blake, Satadru K Lahiri, Xander H T Wehrens, Kurt W Prins
Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation 150 (8) (2024)
Sasha Z Prisco, Lynn M Hartweck, Felipe Kazmirczak, Jenna B Mendelson, Stephanie L Deng, Madelyn J Blake, Satadru K Lahiri, Xander H T Wehrens, Kurt W Prins
Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation 150 (8) (2024)
Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y Abdelnasser, M David Stewart, Satadru K Lahiri, Xander H T Wehrens, Bradley K McConnell
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. Circulation research 134 (8) (2024)
Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y Abdelnasser, M David Stewart, Satadru K Lahiri, Xander H T Wehrens, Bradley K McConnell
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. Circulation research 134 (8) (2024)
Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y Abdelnasser, M David Stewart, Satadru K Lahiri, Xander H T Wehrens, Bradley K McConnell
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. Circulation research 134 (8) (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
Joshua A Keefe, Shuai Zhao, Xander H T Wehrens
A mechanistic LNK between inflammation and atrial fibrillation? Cardiovascular research 120 (8) (2024)
Satadru K Lahiri, Feng Jin, Yue Zhou, Ann P Quick, Carlos F Kramm, Meng C Wang, Xander H T Wehrens
Altered myocardial lipid regulation in junctophilin-2-associated familial cardiomyopathies. Life science alliance 7 (5) (2024)
Joshua A Keefe, Shuai Zhao, Xander H T Wehrens
A mechanistic LNK between inflammation and atrial fibrillation? Cardiovascular research 120 (8) (2024)
Sasha Z Prisco, Lynn M Hartweck, Felipe Kazmirczak, Jenna B Mendelson, Stephanie L Deng, Madelyn J Blake, Satadru K Lahiri, Xander H T Wehrens, Kurt W Prins
Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation 150 (8) (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
Sasha Z Prisco, Lynn M Hartweck, Felipe Kazmirczak, Jenna B Mendelson, Stephanie L Deng, Madelyn J Blake, Satadru K Lahiri, Xander H T Wehrens, Kurt W Prins
Junctophilin-2 Regulates Mitochondrial Metabolism. Circulation 150 (8) (2024)
Joshua A Keefe, Shuai Zhao, Xander H T Wehrens
A mechanistic LNK between inflammation and atrial fibrillation? Cardiovascular research (2024)
Satadru K Lahiri, Feng Jin, Yue Zhou, Ann P Quick, Carlos F Kramm, Meng C Wang, Xander H T Wehrens
Altered myocardial lipid regulation in junctophilin-2-associated familial cardiomyopathies. Life science alliance 7 (5) (2024)
Joshua A Keefe, Xander H T Wehrens
Blocking p38γ/δ, a molecular cardiac defibrillator. Nature cardiovascular research 2 (12) (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
Parisa Asghari, David R L Scriven, Saba Shahrasebi, Héctor H Valdivia, Katherina M Alsina, Carmen R Valdivia, José Alberto Navarro-García, Xander H T Wehrens, Edwin D W Moore
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers. The Journal of general physiology 156 (4) (2024)
José Alberto Navarro-García, Florian Bruns, Oliver M Moore, Marcel A Tekook, Dobromir Dobrev, Christina Y Miyake, Xander H T Wehrens
In Vivo Cardiac Electrophysiology in Mice: Determination of Atrial and Ventricular Arrhythmic Substrates. Current protocols 4 (2) (2024)
Oliver M Moore, Joshua A Keefe, Xander H T Wehrens
Endothelial cell dysfunction: the culprit for cardiac denervation in aging? The journal of cardiovascular aging 3 (4) (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology 16 (2) (2023)
Srikanth Perike, Francisco J Gonzalez-Gonzalez, Issam H Abu-Taha, Frederick W Damen, Laurin M Hanft, Ken S Lizama, Anahita Aboonabi, Andrielle E Capote, Yuriana Aguilar-Sanchez, Benjamin S Levin, Zhenbo Han, Arvind Sridhar, Jacob Grand, Jody L Martin, Joseph G Akar, Chad M Warren, R John Solaro, Sang-Ging Ong, Dawood Darbar, Kerry S McDonald, Craig J Goergen, Beata M Wolska, Dobromir Dobrev, Xander H T Wehrens, Mark D McCauley
PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation. Circulation research (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology 16 (2) (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology 16 (2) (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology 16 (2) (2023)
Oliver M Moore, Joshua A Keefe, Xander H T Wehrens
Endothelial cell dysfunction: the culprit for cardiac denervation in aging? The journal of cardiovascular aging 3 (4) (2023)
Jose Alberto Navarro-Garcia, Satadru K Lahiri, Yuriana Aguilar-Sanchez, Anilkumar K Reddy, Xander H T Wehrens
Characterization of atrial and ventricular remodeling in an improved minimally invasive mouse model of transverse aortic constriction. The journal of cardiovascular aging 3 (3) (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology 16 (2) (2023)
Andrew P Landstrom, Qixin Yang, Bo Sun, Robin M Perelli, Minu-Tshyeto K Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M Alsina, Shuyi Cao, Julia O Reynolds, Tarah A Word, Niels M R van der Sangen, Quinn S Wells, Prince J Kannankeril, Andreas Ludwig, Jeffrey J Kim, Xander H T Wehrens
Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-Driven Increase in Nodal Cell Automaticity. Circulation. Arrhythmia and electrophysiology 16 (2) (2023)
Oliver M Moore, Kevin S Ho, Juwan S Copeland, Vaidya Parthasarathy, Xander H T Wehrens
Genome Editing and Cardiac Arrhythmias. Cells 12 (10) (2023)
Srikanth Perike, Francisco J Gonzalez-Gonzalez, Issam H Abu-Taha, Frederick W Damen, Ken S Lizama, Anahita Aboonabi, Andrielle E Capote, Yuriana Aguilar-Sanchez, Benjamin S Levin, Zhenbo Han, Arvind Sridhar, Jacob Grand, Jody L Martin, Joseph G Akar, Chad M Warren, R John Solaro, Sang-Ging Ong, Dawood Darbar, Craig J Goergen, Beata M Wolska, Dobromir Dobrev, Xander H T Wehrens, Mark D McCauley
Myosin Light Chain Dephosphorylation by PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation. bioRxiv : the preprint server for biology (2023)
Joshua A Keefe, Oliver M Moore, Kevin S Ho, Xander H T Wehrens
Role of Ca 2+ in healthy and pathologic cardiac function: from normal excitation-contraction coupling to mutations that cause inherited arrhythmia. Archives of toxicology (2022)
Hadley Stevens Smith, Clarissa E Sanchez, Ronald Maag, Alexandria Buentello, David R Murdock, Ginger A Metcalf, Trevor D Hadley, Daniel L Riconda, Eric Boerwinkle, Xander H T Wehrens, Christie M Ballantyne, Richard A Gibbs, Amy L McGuire, Stacey Pereira
Patient and Clinician Perceptions of Precision Cardiology Care: Findings From the HeartCare Study. Circulation. Genomic and precision medicine (2022)
Joshua A Keefe, Mohit M Hulsurkar, Svetlana Reilly, Xander H T Wehrens
Mouse models of spontaneous atrial fibrillation. Mammalian genome : official journal of the International Mammalian Genome Society (2022)
Joshua A Keefe, Xander H T Wehrens, Dobromir Dobrev
Common disease-promoting signalling pathways in heart failure and atrial fibrillation: putative underlying mechanisms and potential therapeutic consequences. Cardiovascular research 118 (11) (2022)
Hannah Campbell, Yuriana Aguilar-Sanchez, Ann P Quick, Dobromir Dobrev, Xander H T Wehrens
SPEG: a key regulator of cardiac calcium homeostasis. Cardiovascular research 117 (10) (2022)
Stephan E Lehnart, Xander H T Wehrens
The role of junctophilin proteins in cellular function. Physiological reviews 102 (3) (2022)
Eric Himelman, Julie Nouet, Mauricio A Lillo, Alexander Chong, Delong Zhou, Xander H T Wehrens, George G Rodney, Lai-Hua Xie, Natalia Shirokova, Jorge E Contreras, Diego Fraidenraich
A microtubule-connexin-43 regulatory link suppresses arrhythmias and cardiac fibrosis in Duchenne muscular dystrophy mice. American journal of physiology. Heart and circulatory physiology 323 (5) (2022)
Mohit M Hulsurkar, Satadru K Lahiri, Jason Karch, Meng C Wang, Xander H T Wehrens
Targeting calcium-mediated inter-organellar crosstalk in cardiac diseases. Expert opinion on therapeutic targets 26 (4) (2022)
Joshua A Keefe, José Alberto Navarro-García, Li Ni, Svetlana Reilly, Dobromir Dobrev, Xander H T Wehrens
In-depth characterization of a mouse model of postoperative atrial fibrillation. The journal of cardiovascular aging 2 (2022)
Tarah A Word, Ann P Quick, Christina Y Miyake, Mayra K Shak, Xiaolu Pan, Jean J Kim, Hugh D Allen, Martha Sibrian-Vazquez, Robert M Strongin, Andrew P Landstrom, Xander H T Wehrens
Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell-derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia. Journal of cellular and molecular medicine (2021)
David Y Chiang, Satadru K Lahiri, Guoliang Wang, Jason Karch, Meng C Wang, Sung Yun Jung, Albert J R Heck, Arjen Scholten, Xander H T Wehrens
Phosphorylation-Dependent Interactome of Ryanodine Receptor Type 2 in the Heart. Proteomes 9 (2) (2021)
Satadru K Lahiri, Yuriana Aguilar-Sanchez, Xander H T Wehrens
Mechanisms underlying pathological Ca2+ handling in diseases of the heart. Pflugers Archiv : European journal of physiology 473 (3) (2021)
Mohit M Hulsurkar, Satadru K Lahiri, Oliver Moore, Lucia M Moreira, Issam Abu-Taha, Markus Kamler, Dobromir Dobrev, Stanley Nattel, Svetlana Reilly, Xander H T Wehrens
Atrial-Specific LKB1 Knockdown Represents a Novel Mouse Model of Atrial Cardiomyopathy With Spontaneous Atrial Fibrillation. Circulation 144 (11) (2021)
Lucia M Moreira, Abhijit Takawale, Mohit M Hulsurkar, David A Menassa, Agne Antanaviciute, Satadru K Lahiri, Neelam Mehta, Neil Evans, Constantinos Psarros, Paul Robinson, Alexander J Sparrow, Marc-Antoine Gillis, Neil Ashley, Patrice Naud, Javier Barallobre-Barreiro, Konstantinos Theofilatos, Angela Lee, Mary Norris, Michele V Clarke, Patricia K Russell, Barabara Casadei, Shoumo Bhattacharya, Jeffrey D Zajac, Rachel A Davey, Martin Sirois, Adam J Mead, Alison Simmons, Manuel Mayr, Rana Sayeed, George Krasopoulos, Charles Redwood, Keith M Channon, Jean-Claude Tardif, Xander H T Wehrens, Stanley Nattel, Svetlana Reilly
Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia. Nature 587 (7834) (2020)
Dobromir Dobrev, Xander H T Wehrens
Calcium-mediated cellular triggered activity in atrial fibrillation. The Journal of physiology 595 (12) (2017)
Marilen Federico, Enrique L Portiansky, Leandro Sommese, Francisco J Alvarado, Paula G Blanco, Carolina N Zanuzzi, John Dedman, Marcia Kaetzel, Xander H T Wehrens, Alicia Mattiazzi, Julieta Palomeque
Calcium-calmodulin-dependent protein kinase mediates the intracellular signalling pathways of cardiac apoptosis in mice with impaired glucose tolerance. The Journal of physiology 595 (12) (2017)