Enhanced expression of two discrete isoforms of matrix metalloproteinase-2 in experimental and human diabetic nephropathy.
Sang Soo KimNari ShinSun Sik BaeMin Young LeeHarin RheeIl Young KimEun Young SeongDong Won LeeSoo Bong LeeIhm Soo KwakDavid H LovettSang Heon SongPublished in: PloS one (2017)
The expression of both isoforms of MMP-2 was enhanced in an experimental model of diabetic nephropathy and in human diabetic nephropathy. Selective MMP-2 isoform inhibition could offer a novel approach for the treatment of diabetic renal disease.