Toxicology and applied pharmacology

Keyphrases

Publications

volume 491, 2024

Xiaohan Sun, Weiting Huang, Dejin Yin, Xi Zhao, Xiaoling Cheng, Jin Zhang, Yue Hao
Nicotinamide riboside activates SIRT3 to prevent paclitaxel-induced peripheral neuropathy. Toxicology and applied pharmacology 491 (2024)
Qingfeng He, Min Li, Peiying Ji, Aole Zheng, Li Yao, Xiao Zhu, Jae-Gook Shin, Volker M Lauschke, Bing Han, Xiaoqiang Xiang
Comparison of drug-induced liver injury risk between propylthiouracil and methimazole: A quantitative systems toxicology approach. Toxicology and applied pharmacology 491 (2024)
Kang Wu, Chentao Qiu, Qihong Ma, Fangfang Chen, Tiangong Lu
The anti-cancer mechanism of Celastrol by targeting JAK2/STAT3 signaling pathway in gastric and ovarian cancer. Toxicology and applied pharmacology 491 (2024)
Suyu Chen, Kuangdee Chen, Yihsiu Lin, Ssuchia Wang, Huichuan Yu, Chaohsuan Chang, Tingchun Cheng, Chiaoyun Hsieh, Jiayi Li, Hsiaohsuan Lai, Denghai Chen, Chengpo Huang
Ganoderic acid T, a Ganoderma triterpenoid, modulates the tumor microenvironment and enhances the chemotherapy and immunotherapy efficacy through downregulating galectin-1 levels. Toxicology and applied pharmacology 491 (2024)
Laimar C Garmo, Mackenzie K Herroon, Shane Mecca, Alexis Wilson, David R Allen, Manisha Agarwal, Seongho Kim, Michael C Petriello, Izabela Podgorski
The long-chain polyfluorinated alkyl substance perfluorohexane sulfonate (PFHxS) promotes bone marrow adipogenesis. Toxicology and applied pharmacology 491 (2024)
Guan Wang, Chun Wang, Pengcheng Zhu, Jiaxin Tian, Haitao Yang
The protective mechanism of sevoflurane in pulmonary arterial hypertension via downregulation of TRAF6. Toxicology and applied pharmacology 491 (2024)
Mustafa O Sharaf El-Deen, Moetaza M Soliman, Gamal Al-Azab, Mohamed Samra, Mohammad E E Shams
Post-transplantation cyclophosphamide and cyclosporine A versus methotrexate and cyclosporine A for graft-versus-host disease prophylaxis after allogeneic peripheral stem cell transplantation in adult acute myeloid leukemia patients. Toxicology and applied pharmacology 491 (2024)
Mohamed Gamal El-Din Ewees, Gomaa Mostafa-Hadeab, Sameh Saber, Eman Ali Abd El-Meguid, Haidy Tamer Abo Sree, Fatema El-Zahraa S Abdel Rahman, Nesreen Ishak Mahmoud
Linagliptin mitigates cisplatin-induced kidney impairment via mitophagy regulation in rats, with emphasis on SIRT-3/PGC-1α, PINK-1 and Parkin-2. Toxicology and applied pharmacology 491 (2024)
Joseph L Bundy, Logan J Everett, Jesse D Rogers, Jo Nyffeler, Gabrielle Byrd, Megan Culbreth, Derik E Haggard, Laura J Word, Bryant A Chambers, Sarah Davidson-Fritz, Felix Harris, Clinton Willis, Katie Paul-Friedman, Imran Shah, Richard Judson, Joshua A Harrill
High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells. Toxicology and applied pharmacology 491 (2024)
Fabiane Bicca Obetine Baptista, Aline Franzen da Silva, Larissa Marafiga Cordeiro, Larissa Ilha de Souza, Tássia Limana da Silveira, Marcell Valandro Soares, Paula Michelotti, Cristiane Lenz Dalla Corte, Rafael Santos da Silva, Oscar Endrigo Dorneles Rodrigues, Leticia Priscilla Arantes, Félix Alexandre Antunes Soares
Biosafety assessment of novel organoselenium zidovudine derivatives in the Caenorhabditis elegans model. Toxicology and applied pharmacology 491 (2024)
Renshan Chen, Anran Zheng, Yunjing Wang, Liyou Guo, Huaqian Dou, Liangyan Lu, Muhammad Rafiq, Peihua Li, Xiuhui Chen, Qing Xiao
Salvianolic acid B improves mitochondrial dysfunction of septic cardiomyopathy via enhancing ATF5-mediated mitochondrial unfolded protein response. Toxicology and applied pharmacology 491 (2024)
Małgorzata Borkowska-Sztachańska, Michael Thoene, Katarzyna Socha, Jerzy Juśkiewicz, Michał S Majewski
Decreased vascular contraction and changes in oxidative state in middle-aged Wistar rats after exposure to increased levels of dietary zinc. Toxicology and applied pharmacology 491 (2024)
Enio Setsuo Arakaki Pacini, Raíssa de Paula Moro, Rosely Oliveira Godinho
Extracellular cAMP elicits contraction of rat vas deferens: Involvement of ecto-5'-nucleotidase and adenosine A 1 receptors. Toxicology and applied pharmacology 491 (2024)
Rose A Willett, Volodymyr P Tryndyak, Jennifer M Hughes Hanks, Lana Elkins, Suresh K Nagumalli, Mark I Avigan, Sharon A Ross, Gonçalo Gamboa da Costa, Frederick A Beland, Ivan Rusyn, Igor P Pogribny
A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice. Toxicology and applied pharmacology 491 (2024)
Nanthip Prathumsap, Benjamin Ongnok, Thawatchai Khuanjing, Apiwan Arinno, Chayodom Maneechote, Titikorn Chunchai, Busarin Arunsak, Sasiwan Kerdphoo, Siriporn C Chattipakorn, Nipon Chattipakorn
Muscarinic and nicotinic receptors stimulation by vagus nerve stimulation ameliorates trastuzumab-induced cardiotoxicity via reducing programmed cell death in rats. Toxicology and applied pharmacology 491 (2024)
Yujiao Chen, Jingyu Wang, Wei Zhang, Xiaoli Guo, Jing Ren, Lei Zhang, Ai Gao
Extracellular vesicles-derived long noncoding RNAs participated in benzene hematotoxicity by mediating apoptosis and autophagy. Toxicology and applied pharmacology 491 (2024)
Miao Yang, Kanmin Mao, Xin Cao, Hongjuan Liu, Weifeng Mao, Liping Hao
Integrated network toxicology, transcriptomics and gut microbiomics reveals hepatotoxicity mechanism induced by benzo[a]pyrene exposure in mice. Toxicology and applied pharmacology 491 (2024)
Chengjin Zhao, Yangyang Feng, Yuhu Zhou, Nannan Li, Li Zhao
Artesunate attenuates osteoarthritis in mice by promoting MTA1 transcription through a USP7/FoxO1 axis. Toxicology and applied pharmacology 491 (2024)

volume 490, 2024

Yuese Yuan, Yimeng Zhuang, Yuan Cui, Yuetong Liu, Qiong Zhang, Qianqian Xiao, Qinghe Meng, Jianjun Jiang, Weidong Hao, Xuetao Wei
Effects of 1, 2-bis (2,4, 6-tribromophenoxy) ethane and bis (2-ethylhexyl) tetrabromophthalate on serum metabolic and lipid profiles in male rats. Toxicology and applied pharmacology 490 (2024)
Zahra Fathi, Armen Avanes, Zohreh Jahanafrooz
In vitro study on the anticancer effects of oxalipalladium against PC3 human prostate carcinoma cells. Toxicology and applied pharmacology 490 (2024)
Junfeng Kang, Lishi Jie, Guozhen Lu, Houyu Fu, Taiyang Liao, Deren Liu, Lei Shi, Songjiang Yin, Li Zhang, Peimin Wang
Gallic acid ameliorates synovial inflammation and fibrosis by regulating the intestinal flora and its metabolites. Toxicology and applied pharmacology 490 (2024)
Margarida L F Martins, Paniz Heydari, Wenlong Li, Alejandra Martínez-Chávez, Malika El Yattouti, Maria C Lebre, Jos H Beijnen, Alfred H Schinkel
The role of drug efflux and uptake transporters in the plasma pharmacokinetics and tissue disposition of morphine and its main metabolites. Toxicology and applied pharmacology 490 (2024)
Wesam H Abdulaal, Ulfat M Omar, Mustafa Zeyadi, Dina S El-Agamy, Nabil A Alhakamy, Sabrin R M Ibrahim, Naif A R Almalki, Hani Z Asfour, Mohammed W Al-Rabia, Gamal A Mohamed, Mahmoud Elshal
Pirfenidone ameliorates ANIT-induced cholestatic liver injury via modulation of FXR, NF-кB/TNF-α, and Wnt/GSK-3β/β-catenin signaling pathways. Toxicology and applied pharmacology 490 (2024)
Amrutha Nedumbrakkad Kunnath, Shravani Kanakadas Parker, Daphne Norma Crasta, Jyolsna Ponnaratta Kunhiraman, Vanishree Vasave Madhvacharya, Sandhya Kumari, Guruprasad Nayak, R Vani Lakshmi, Prashanth Kumar Modi, Thottethodi Subrahmanya Keshava Prasad, Anujith Kumar, Ayush Khandelwal, Nadeem Khan Ghani, Shama Prasada Kabekkodu, Satish Kumar Adiga, Guruprasad Kalthur
Metformin augments major cytoplasmic organization except for spindle organization in oocytes cultured under hyperglycemic and hyperlipidemic conditions: An in vitro study. Toxicology and applied pharmacology 490 (2024)
Junfeng Kang, Lishi Jie, Guozhen Lu, Houyu Fu, Taiyang Liao, Deren Liu, Lei Shi, Songjiang Yin, Li Zhang, Peimin Wang
Gallic acid ameliorates synovial inflammation and fibrosis by regulating the intestinal flora and its metabolites. Toxicology and applied pharmacology 490 (2024)
Haiyun Huang, Xiaojun Li, Yican Deng, Siyi San, Dongmei Qiu, Ao Xu, Jiyu Luo, Lingyun Xu, Yang Li, Hongling Zhang, Yuanyuan Li
Associations between prenatal exposure to per- and polyfluoroalkyl substances and plasma immune molecules in three-year-old children in China. Toxicology and applied pharmacology 490 (2024)
Madison Stoddard, Lin Yuan, Jodi Cooper, Christine Carcillo Neumar, Barbara Hibner, Humphrey Gardner, Arijit Chakravarty
Can we do better with Mylotarg? Model-based assessment of opportunities to improve therapeutic index. Toxicology and applied pharmacology 490 (2024)
Mervenur Yavuz, Turan Demircan
Exploring the potentials of S4, a selective androgen receptor modulator, in glioblastoma multiforme therapy. Toxicology and applied pharmacology 490 (2024)
Mervenur Yavuz, Turan Demircan
Exploring the potentials of S4, a selective androgen receptor modulator, in glioblastoma multiforme therapy. Toxicology and applied pharmacology 490 (2024)
Asmaa S Elzaitony, Aya H Al-Najjar, Asmaa A Gomaa, Ayat M S Eraque, Amany Said Sallam
Re-positioning of low dose paclitaxel against depressive-like behavior and neuroinflammation induced by lipopolysaccharide in rats: Crosstalk between NLRP3/caspase-1/IL-1β and Sphk1/S1P/ NF-κB signaling pathways. Toxicology and applied pharmacology 490 (2024)
Yuese Yuan, Yimeng Zhuang, Yuan Cui, Yuetong Liu, Qiong Zhang, Qianqian Xiao, Qinghe Meng, Jianjun Jiang, Weidong Hao, Xuetao Wei
Effects of 1, 2-bis (2,4, 6-tribromophenoxy) ethane and bis (2-ethylhexyl) tetrabromophthalate on serum metabolic and lipid profiles in male rats. Toxicology and applied pharmacology 490 (2024)
Nada A M Ali, Amir Mohamed Abdelhamid, Norhan M El-Sayed, Asmaa Radwan
Alpha-Asarone attenuates alcohol-induced hepatotoxicity in a murine model by ameliorating oxidative stress, inflammation, and modulating apoptotic-Autophagic cell death. Toxicology and applied pharmacology 490 (2024)
Xinyun Zhao, Xinping Zhu, Honglei Tao, Hongling Zou, Jili Cao, Yuxin Chen, Ziru Zhang, Yongqiang Zhu, Qun Li, Mingqian Li
Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism. Toxicology and applied pharmacology 490 (2024)
Haiyun Huang, Xiaojun Li, Yican Deng, Siyi San, Dongmei Qiu, Ao Xu, Jiyu Luo, Lingyun Xu, Yang Li, Hongling Zhang, Yuanyuan Li
Associations between prenatal exposure to per- and polyfluoroalkyl substances and plasma immune molecules in three-year-old children in China. Toxicology and applied pharmacology 490 (2024)
Margarida L F Martins, Paniz Heydari, Wenlong Li, Alejandra Martínez-Chávez, Malika El Yattouti, Maria C Lebre, Jos H Beijnen, Alfred H Schinkel
The role of drug efflux and uptake transporters in the plasma pharmacokinetics and tissue disposition of morphine and its main metabolites. Toxicology and applied pharmacology 490 (2024)
Asmaa S Elzaitony, Aya H Al-Najjar, Asmaa A Gomaa, Ayat M S Eraque, Amany Said Sallam
Re-positioning of low dose paclitaxel against depressive-like behavior and neuroinflammation induced by lipopolysaccharide in rats: Crosstalk between NLRP3/caspase-1/IL-1β and Sphk1/S1P/ NF-κB signaling pathways. Toxicology and applied pharmacology 490 (2024)
Nada A M Ali, Amir Mohamed Abdelhamid, Norhan M El-Sayed, Asmaa Radwan
Alpha-Asarone attenuates alcohol-induced hepatotoxicity in a murine model by ameliorating oxidative stress, inflammation, and modulating apoptotic-Autophagic cell death. Toxicology and applied pharmacology 490 (2024)
Xue Xiao, Yali Lei, Tong Yao, Tingting Huang, Pingping Yan, Lei Cao, Yongxiao Cao
PM 10 exposure induces bronchial hyperresponsiveness by upreguating acetylcholine muscarinic 3 receptor. Toxicology and applied pharmacology 490 (2024)
Xinyun Zhao, Xinping Zhu, Honglei Tao, Hongling Zou, Jili Cao, Yuxin Chen, Ziru Zhang, Yongqiang Zhu, Qun Li, Mingqian Li
Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism. Toxicology and applied pharmacology 490 (2024)
Esraa M Samy, Rasha R Radwan, Farag M Mosallam, Heba A Mohamed
Ameliorative effect of nano-pregabalin in gastrocnemius muscle of gamma irradiated rats with an experimental model of fibromyalgia: Crosstalk of Sirt3, IL-1β and PARP1 pathways. Toxicology and applied pharmacology 490 (2024)
Ye Ding, Hao Li, Saisai Cao, Yong Yu
Effects of catechin on the malignant biological behavior of gastric cancer cells through the PI3K/Akt signaling pathway. Toxicology and applied pharmacology 490 (2024)
Marek Grosicki, Kamila Wojnar-Lason, Sylwester Mosiolek, Lukasz Mateuszuk, Marta Stojak, Stefan Chlopicki
Distinct profile of antiviral drugs effects in aortic and pulmonary endothelial cells revealed by high-content microscopy and cell painting assays. Toxicology and applied pharmacology 490 (2024)
Madison Stoddard, Lin Yuan, Jodi Cooper, Christine Carcillo Neumar, Barbara Hibner, Humphrey Gardner, Arijit Chakravarty
Can we do better with Mylotarg? Model-based assessment of opportunities to improve therapeutic index. Toxicology and applied pharmacology 490 (2024)
Amrutha Nedumbrakkad Kunnath, Shravani Kanakadas Parker, Daphne Norma Crasta, Jyolsna Ponnaratta Kunhiraman, Vanishree Vasave Madhvacharya, Sandhya Kumari, Guruprasad Nayak, R Vani Lakshmi, Prashanth Kumar Modi, Thottethodi Subrahmanya Keshava Prasad, Anujith Kumar, Ayush Khandelwal, Nadeem Khan Ghani, Shama Prasada Kabekkodu, Satish Kumar Adiga, Guruprasad Kalthur
Metformin augments major cytoplasmic organization except for spindle organization in oocytes cultured under hyperglycemic and hyperlipidemic conditions: An in vitro study. Toxicology and applied pharmacology 490 (2024)
Wesam H Abdulaal, Ulfat M Omar, Mustafa Zeyadi, Dina S El-Agamy, Nabil A Alhakamy, Sabrin R M Ibrahim, Naif A R Almalki, Hani Z Asfour, Mohammed W Al-Rabia, Gamal A Mohamed, Mahmoud Elshal
Pirfenidone ameliorates ANIT-induced cholestatic liver injury via modulation of FXR, NF-кB/TNF-α, and Wnt/GSK-3β/β-catenin signaling pathways. Toxicology and applied pharmacology 490 (2024)
Marek Grosicki, Kamila Wojnar-Lason, Sylwester Mosiolek, Lukasz Mateuszuk, Marta Stojak, Stefan Chlopicki
Distinct profile of antiviral drugs effects in aortic and pulmonary endothelial cells revealed by high-content microscopy and cell painting assays. Toxicology and applied pharmacology 490 (2024)
Zahra Fathi, Armen Avanes, Zohreh Jahanafrooz
In vitro study on the anticancer effects of oxalipalladium against PC3 human prostate carcinoma cells. Toxicology and applied pharmacology 490 (2024)
Xue Xiao, Yali Lei, Tong Yao, Tingting Huang, Pingping Yan, Lei Cao, Yongxiao Cao
PM 10 exposure induces bronchial hyperresponsiveness by upreguating acetylcholine muscarinic 3 receptor. Toxicology and applied pharmacology 490 (2024)
Esraa M Samy, Rasha R Radwan, Farag M Mosallam, Heba A Mohamed
Ameliorative effect of nano-pregabalin in gastrocnemius muscle of gamma irradiated rats with an experimental model of fibromyalgia: Crosstalk of Sirt3, IL-1β and PARP1 pathways. Toxicology and applied pharmacology 490 (2024)
Ye Ding, Hao Li, Saisai Cao, Yong Yu
Effects of catechin on the malignant biological behavior of gastric cancer cells through the PI3K/Akt signaling pathway. Toxicology and applied pharmacology 490 (2024)