Biopharmaceutics & drug disposition

Keyphrases

Publications

2024

Wolfgang Löscher, Martina Gramer, Kerstin Römermann
Heterogeneous brain distribution of bumetanide following systemic administration in rats. Biopharmaceutics & drug disposition (2024)
Manoj Gundeti, Aditya Murthy, Shubham Jamdade, Tausif Ahmed
Evaluating gender effect in the generic bioequivalence studies by physiologically based pharmacokinetic modeling - A case study of dextromethorphan modified release tablets. Biopharmaceutics & drug disposition (2024)
Kohei Yamada, Kurt D Ristroph, Yuuki Kaneko, Hoang D Lu, Robert K Prud'homme, Hideyuki Sato, Satomi Onoue
Pharmacokinetic control of orally dosed cyclosporine A with mucosal drug delivery system. Biopharmaceutics & drug disposition (2024)
Yi Rong, Nanxi Li, Xuan Qiao, Lei Yang, Peng Han, Zhiyun Meng, Hui Gan, Zhuona Wu, Xiaoxia Zhu, Yunbo Sun, Shuchen Liu, Guifang Dou, Ruolan Gu
Icaritin exhibits potential drug-drug interactions through the inhibition of human UDP-glucuronosyltransferase in vitro. Biopharmaceutics & drug disposition (2024)
Teng Meng, Donald Jung, Xiao-Hong Cai, Zhao-Qiang Lu, Ji-Bing Yu, Tian-Yang Qi, Fan-Ying Meng, Mei-Zhen Ruan, Jian-Xin Duan
Characterization of AST-001 non-clinical pharmacokinetics: A novel selective AKR1C3-activated prodrug in mice, rats, and cynomolgus monkeys. Biopharmaceutics & drug disposition (2024)
Guilan Yu, Xueying Zhou
Gender difference in the pharmacokinetics and metabolism of VX-548 in rats. Biopharmaceutics & drug disposition (2024)
Hyo-Jeong Ryu, Seongsung Kwak, Misun Park, Hwi-Yeol Yun
Model-based interspecies interpretation of botulinum neurotoxin type A on muscle-contraction inhibition. Biopharmaceutics & drug disposition (2024)
K Sandy Pang, H Benson Peng, Betty P Li, Binyu Wen, Keumhan Noh, Runyu Xia, Anja Toscan, Sylvia Serson, Paul E Fraser, Rommel G Tirona, Inès A M de Lannoy
Aging and brain free cholesterol concentration on amyloid-β peptide accumulation in guinea pigs. Biopharmaceutics & drug disposition (2024)
Ahmed M Elmeniar, Mohamed A Osman, Sanaa A El-Gizawy, Dimple Modi, Nitin B Charbe, Ayman F El-Kattan, Mohamed El-Tanani, Yusuf A Haggag, Murtaza M Tambuwala
In situ evaluation of the impact of metformin or verapamil coadministration with vildagliptin on its regional absorption from the rabbit's intestine. Biopharmaceutics & drug disposition (2024)
Abhishek Pathak, Satya Pal Singh, Dev Bukhsh Singh, Pranav Anjaria, Apoorv Tiwari
Computational exploration of microsomal cytochrome P450 3A1 enzyme modulation by phytochemicals of Cichorium intybus L.: Insights into drug metabolism. Biopharmaceutics & drug disposition (2024)
Yanrong Ma, Xinyi Wang, Xueyan Gou, Xin-An Wu
Identification and characterization of an endogenous biomarker of the renal vectorial transport (OCT2-MATE1). Biopharmaceutics & drug disposition (2024)
Jing Ling, Xuping Yang, Lulu Dong, Yan Jiang, Sulan Zou, Nan Hu
Utility of cystatin C and serum creatinine-based glomerular filtration rate equations in predicting vancomycin clearance: A population pharmacokinetics analysis in elderly Chinese patients. Biopharmaceutics & drug disposition (2024)
Cui Li, Xiaokun Li, Ali Fan, Ning He, Dongmei Wu, Hongyan Yu, Kun Wang, Weijie Jiao, Xu Zhao
Evidence for cytochrome P450 3A4-mediated metabolic activation of SCO-267. Biopharmaceutics & drug disposition (2024)

volume 45, number 1, 2024

Cui Li, Xiaokun Li, Ali Fan, Ning He, Dongmei Wu, Hongyan Yu, Kun Wang, Weijie Jiao, Xu Zhao
Evidence for cytochrome P450 3A4-mediated metabolic activation of SCO-267. Biopharmaceutics & drug disposition 45 (1) (2024)
Yanrong Ma, Xinyi Wang, Xueyan Gou, Xin-An Wu
Identification and characterization of an endogenous biomarker of the renal vectorial transport (OCT2-MATE1). Biopharmaceutics & drug disposition 45 (1) (2024)
Jing Ling, Xuping Yang, Lulu Dong, Yan Jiang, Sulan Zou, Nan Hu
Utility of cystatin C and serum creatinine-based glomerular filtration rate equations in predicting vancomycin clearance: A population pharmacokinetics analysis in elderly Chinese patients. Biopharmaceutics & drug disposition 45 (1) (2024)
Jing Ling, Xuping Yang, Lulu Dong, Yan Jiang, Sulan Zou, Nan Hu
Utility of cystatin C and serum creatinine-based glomerular filtration rate equations in predicting vancomycin clearance: A population pharmacokinetics analysis in elderly Chinese patients. Biopharmaceutics & drug disposition 45 (1) (2024)
Abhishek Pathak, Satya Pal Singh, Dev Bukhsh Singh, Pranav Anjaria, Apoorv Tiwari
Computational exploration of microsomal cytochrome P450 3A1 enzyme modulation by phytochemicals of Cichorium intybus L.: Insights into drug metabolism. Biopharmaceutics & drug disposition 45 (1) (2024)
Abhishek Pathak, Satya Pal Singh, Dev Bukhsh Singh, Pranav Anjaria, Apoorv Tiwari
Computational exploration of microsomal cytochrome P450 3A1 enzyme modulation by phytochemicals of Cichorium intybus L.: Insights into drug metabolism. Biopharmaceutics & drug disposition 45 (1) (2024)
Yanrong Ma, Xinyi Wang, Xueyan Gou, Xin-An Wu
Identification and characterization of an endogenous biomarker of the renal vectorial transport (OCT2-MATE1). Biopharmaceutics & drug disposition 45 (1) (2024)
Cui Li, Xiaokun Li, Ali Fan, Ning He, Dongmei Wu, Hongyan Yu, Kun Wang, Weijie Jiao, Xu Zhao
Evidence for cytochrome P450 3A4-mediated metabolic activation of SCO-267. Biopharmaceutics & drug disposition 45 (1) (2024)
Jing Ling, Xuping Yang, Lulu Dong, Yan Jiang, Sulan Zou, Nan Hu
Utility of cystatin C and serum creatinine-based glomerular filtration rate equations in predicting vancomycin clearance: A population pharmacokinetics analysis in elderly Chinese patients. Biopharmaceutics & drug disposition 45 (1) (2024)

volume 45, number 2, 2024

Teng Meng, Donald Jung, Xiao-Hong Cai, Zhao-Qiang Lu, Ji-Bing Yu, Tian-Yang Qi, Fan-Ying Meng, Mei-Zhen Ruan, Jian-Xin Duan
Characterization of AST-001 non-clinical pharmacokinetics: A novel selective AKR1C3-activated prodrug in mice, rats, and cynomolgus monkeys. Biopharmaceutics & drug disposition 45 (2) (2024)
Ahmed M Elmeniar, Mohamed A Osman, Sanaa A El-Gizawy, Dimple Modi, Nitin B Charbe, Ayman F El-Kattan, Mohamed El-Tanani, Yusuf A Haggag, Murtaza M Tambuwala
In situ evaluation of the impact of metformin or verapamil coadministration with vildagliptin on its regional absorption from the rabbit's intestine. Biopharmaceutics & drug disposition 45 (2) (2024)
Teng Meng, Donald Jung, Xiao-Hong Cai, Zhao-Qiang Lu, Ji-Bing Yu, Tian-Yang Qi, Fan-Ying Meng, Mei-Zhen Ruan, Jian-Xin Duan
Characterization of AST-001 non-clinical pharmacokinetics: A novel selective AKR1C3-activated prodrug in mice, rats, and cynomolgus monkeys. Biopharmaceutics & drug disposition 45 (2) (2024)
Guilan Yu, Xueying Zhou
Gender difference in the pharmacokinetics and metabolism of VX-548 in rats. Biopharmaceutics & drug disposition 45 (2) (2024)
Ahmed M Elmeniar, Mohamed A Osman, Sanaa A El-Gizawy, Dimple Modi, Nitin B Charbe, Ayman F El-Kattan, Mohamed El-Tanani, Yusuf A Haggag, Murtaza M Tambuwala
In situ evaluation of the impact of metformin or verapamil coadministration with vildagliptin on its regional absorption from the rabbit's intestine. Biopharmaceutics & drug disposition 45 (2) (2024)
Teng Meng, Donald Jung, Xiao-Hong Cai, Zhao-Qiang Lu, Ji-Bing Yu, Tian-Yang Qi, Fan-Ying Meng, Mei-Zhen Ruan, Jian-Xin Duan
Characterization of AST-001 non-clinical pharmacokinetics: A novel selective AKR1C3-activated prodrug in mice, rats, and cynomolgus monkeys. Biopharmaceutics & drug disposition 45 (2) (2024)
Guilan Yu, Xueying Zhou
Gender difference in the pharmacokinetics and metabolism of VX-548 in rats. Biopharmaceutics & drug disposition 45 (2) (2024)
K Sandy Pang, H Benson Peng, Betty P Li, Binyu Wen, Keumhan Noh, Runyu Xia, Anja Toscan, Sylvia Serson, Paul E Fraser, Rommel G Tirona, Inès A M de Lannoy
Aging and brain free cholesterol concentration on amyloid-β peptide accumulation in guinea pigs. Biopharmaceutics & drug disposition 45 (2) (2024)
K Sandy Pang, H Benson Peng, Betty P Li, Binyu Wen, Keumhan Noh, Runyu Xia, Anja Toscan, Sylvia Serson, Paul E Fraser, Rommel G Tirona, Inès A M de Lannoy
Aging and brain free cholesterol concentration on amyloid-β peptide accumulation in guinea pigs. Biopharmaceutics & drug disposition 45 (2) (2024)

volume 45, number 3, 2024

Manoj Gundeti, Aditya Murthy, Shubham Jamdade, Tausif Ahmed
Evaluating gender effect in the generic bioequivalence studies by physiologically based pharmacokinetic modeling - A case study of dextromethorphan modified release tablets. Biopharmaceutics & drug disposition 45 (3) (2024)
Wolfgang Löscher, Martina Gramer, Kerstin Römermann
Heterogeneous brain distribution of bumetanide following systemic administration in rats. Biopharmaceutics & drug disposition 45 (3) (2024)
Kohei Yamada, Kurt D Ristroph, Yuuki Kaneko, Hoang D Lu, Robert K Prud'homme, Hideyuki Sato, Satomi Onoue
Pharmacokinetic control of orally dosed cyclosporine A with mucosal drug delivery system. Biopharmaceutics & drug disposition 45 (3) (2024)
Manoj Gundeti, Aditya Murthy, Shubham Jamdade, Tausif Ahmed
Evaluating gender effect in the generic bioequivalence studies by physiologically based pharmacokinetic modeling - A case study of dextromethorphan modified release tablets. Biopharmaceutics & drug disposition 45 (3) (2024)
Wolfgang Löscher, Martina Gramer, Kerstin Römermann
Heterogeneous brain distribution of bumetanide following systemic administration in rats. Biopharmaceutics & drug disposition 45 (3) (2024)
Yi Rong, Nanxi Li, Xuan Qiao, Lei Yang, Peng Han, Zhiyun Meng, Hui Gan, Zhuona Wu, Xiaoxia Zhu, Yunbo Sun, Shuchen Liu, Guifang Dou, Ruolan Gu
Icaritin exhibits potential drug-drug interactions through the inhibition of human UDP-glucuronosyltransferase in vitro. Biopharmaceutics & drug disposition 45 (3) (2024)
Yi Rong, Nanxi Li, Xuan Qiao, Lei Yang, Peng Han, Zhiyun Meng, Hui Gan, Zhuona Wu, Xiaoxia Zhu, Yunbo Sun, Shuchen Liu, Guifang Dou, Ruolan Gu
Icaritin exhibits potential drug-drug interactions through the inhibition of human UDP-glucuronosyltransferase in vitro. Biopharmaceutics & drug disposition 45 (3) (2024)

volume 44, number 1, 2023

Anja Haasbroek-Pheiffer, Suzanne Van Niekerk, Frank van der Kooy, Theunis Cloete, Jan Steenekamp, Josias H Hamman
In vitro and ex vivo experimental models for evaluation of intranasal systemic drug delivery as well as direct nose-to-brain drug delivery. Biopharmaceutics & drug disposition 44 (1) (2023)
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, Tracey Boyden, Angela C Doran, Jessica Mancuso, Kenneth Zasadny, Timothy McCarthy, Evan D Morris, Richard E Carson, Irina Esterlis, Yiyun Huang, Nabeel Nabulsi, Beata Planeta, Terence Fullerton
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT 6 receptor occupancy from non-human primates to humans. Biopharmaceutics & drug disposition 44 (1) (2023)
Sagnik Chatterjee, Anup Arunrao Deshpande, Hong Shen
Recent advances in the in vitro and in vivo methods to assess impact of P-glycoprotein and breast cancer resistance protein transporters in central nervous system drug disposition. Biopharmaceutics & drug disposition 44 (1) (2023)
Thomas Altendorfer-Kroath, Joanna Hummer, Thomas Birngruber
In vivo monitoring of brain pharmacokinetics and pharmacodynamics with cerebral open flow microperfusion. Biopharmaceutics & drug disposition 44 (1) (2023)
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, Tracey Boyden, Angela C Doran, Jessica Mancuso, Kenneth Zasadny, Timothy McCarthy, Evan D Morris, Richard E Carson, Irina Esterlis, Yiyun Huang, Nabeel Nabulsi, Beata Planeta, Terence Fullerton
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT 6 receptor occupancy from non-human primates to humans. Biopharmaceutics & drug disposition 44 (1) (2023)
Anja Haasbroek-Pheiffer, Suzanne Van Niekerk, Frank van der Kooy, Theunis Cloete, Jan Steenekamp, Josias H Hamman
In vitro and ex vivo experimental models for evaluation of intranasal systemic drug delivery as well as direct nose-to-brain drug delivery. Biopharmaceutics & drug disposition 44 (1) (2023)
Christine Bowman, Fang Ma, Jialin Mao, Emile Plise, Eugene Chen, Liling Liu, Shu Zhang, Yuan Chen
Evaluation of bottom-up modeling of the blood-brain barrier to improve brain penetration prediction via physiologically based pharmacokinetic modeling. Biopharmaceutics & drug disposition 44 (1) (2023)
Thomas Altendorfer-Kroath, Joanna Hummer, Thomas Birngruber
In vivo monitoring of brain pharmacokinetics and pharmacodynamics with cerebral open flow microperfusion. Biopharmaceutics & drug disposition 44 (1) (2023)
Sagnik Chatterjee, Anup Arunrao Deshpande, Hong Shen
Recent advances in the in vitro and in vivo methods to assess impact of P-glycoprotein and breast cancer resistance protein transporters in central nervous system drug disposition. Biopharmaceutics & drug disposition 44 (1) (2023)
Christine Bowman, Fang Ma, Jialin Mao, Emile Plise, Eugene Chen, Liling Liu, Shu Zhang, Yuan Chen
Evaluation of bottom-up modeling of the blood-brain barrier to improve brain penetration prediction via physiologically based pharmacokinetic modeling. Biopharmaceutics & drug disposition 44 (1) (2023)
Christine Bowman, Fang Ma, Jialin Mao, Emile Plise, Eugene Chen, Liling Liu, Shu Zhang, Yuan Chen
Evaluation of bottom-up modeling of the blood-brain barrier to improve brain penetration prediction via physiologically based pharmacokinetic modeling. Biopharmaceutics & drug disposition 44 (1) (2023)
Aarti Sawant-Basak, Laigao Chen, Peter Lockwood, Tracey Boyden, Angela C Doran, Jessica Mancuso, Kenneth Zasadny, Timothy McCarthy, Evan D Morris, Richard E Carson, Irina Esterlis, Yiyun Huang, Nabeel Nabulsi, Beata Planeta, Terence Fullerton
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT 6 receptor occupancy from non-human primates to humans. Biopharmaceutics & drug disposition 44 (1) (2023)