Acta pharmacologica Sinica

Keyphrases

Publications

volume 45, number 8, 2024

Zhi-Feng Zou, Lei Yang, Hui-Jun Nie, Jing Gao, Shu-Min Lei, Yi Lai, Fan Zhang, Ernst Wagner, Hai-Jun Yu, Xiao-Hua Chen, Zhi-Ai Xu
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy. Acta pharmacologica Sinica 45 (8) (2024)
Xuan Ni, Cheng-Piao Lu, Guo-Qiang Xu, Jing-Jing Ma
Transcriptional regulation and post-translational modifications in the glycolytic pathway for targeted cancer therapy. Acta pharmacologica Sinica 45 (8) (2024)

volume 45, number 9, 2024

Ze-Ka Chen, Yuan-Yuan Liu, Ji-Chuan Zhou, Gui-Hai Chen, Chun-Feng Liu, Wei-Min Qu, Zhi-Li Huang
Insomnia-related rodent models in drug discovery. Acta pharmacologica Sinica 45 (9) (2024)
Ana Beatriz Santos, Andreia Carona, Miren Ettcheto, Antoni Camins, Amílcar Falcão, Ana Fortuna, Joana Bicker
Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis. Acta pharmacologica Sinica 45 (9) (2024)
Zhi-Hua Zheng, Jiao-Jiao Wang, Jiu-Guo Lin, Wei-le Ye, Jia-Mi Zou, Li-Yin Liang, Ping-Lian Yang, Wan-Lu Qiu, Yuan-Yuan Li, Si-Jia Yang, Man Zhao, Qing Zhou, Cheng-Zhi Li, Min Li, Zhuo-Ming Li, Dong-Mei Zhang, Pei-Qing Liu, Zhi-Ping Liu
Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol. Acta pharmacologica Sinica 45 (9) (2024)
Feng-Ting Lu, Cheng-Cui Huang, Wen-Yi Lai, Gui-Yong Yang, Zhu-Jun Liang, Zi-Yi Zhang, Tanvi Chokshi, Kai-Min Guo, Yu-Bo Tang, Yuan Chen, Zhong-Han Yang, Si-Jia Liang, Rui-Ping Pang, Jia-Guo Zhou, Yong-Yuan Guan, Xiao-Fei Lv, Ming-Ming Ma
Vascular smooth muscle-specific LRRC8A knockout ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting the WNK1/FOXO3a/MMP signaling pathway. Acta pharmacologica Sinica 45 (9) (2024)
Feng-Ting Lu, Cheng-Cui Huang, Wen-Yi Lai, Gui-Yong Yang, Zhu-Jun Liang, Zi-Yi Zhang, Tanvi Chokshi, Kai-Min Guo, Yu-Bo Tang, Yuan Chen, Zhong-Han Yang, Si-Jia Liang, Rui-Ping Pang, Jia-Guo Zhou, Yong-Yuan Guan, Xiao-Fei Lv, Ming-Ming Ma
Vascular smooth muscle-specific LRRC8A knockout ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting the WNK1/FOXO3a/MMP signaling pathway. Acta pharmacologica Sinica 45 (9) (2024)
Mo-Ting Liu, Yao Zhang, Cai-Gui Xiang, Tao Yang, Xiao-Han Wang, Qiu-Kai Lu, Hui-Min Lu, Chen Fan, Chun-Lan Feng, Xiao-Qian Yang, Duo-Wu Zou, Heng Li, Wei Tang
Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages. Acta pharmacologica Sinica 45 (9) (2024)
Xiu-Chun Li, Xia-Yan Zhu, Yang-Yue Wang, Shuo-Lan Tong, Zhi-Li Chen, Zi-Yi Lu, Jian-Hao Zhang, Lan-Lan Song, Xing-Hong Wang, Chi Zhang, Yi-Han Sun, Chu-Yue Zhong, Li-Huang Su, Liang-Xing Wang, Xiao-Ying Huang
Canagliflozin alleviates pulmonary hypertension by activating PPARγ and inhibiting its S225 phosphorylation. Acta pharmacologica Sinica 45 (9) (2024)
Feng-Ting Lu, Cheng-Cui Huang, Wen-Yi Lai, Gui-Yong Yang, Zhu-Jun Liang, Zi-Yi Zhang, Tanvi Chokshi, Kai-Min Guo, Yu-Bo Tang, Yuan Chen, Zhong-Han Yang, Si-Jia Liang, Rui-Ping Pang, Jia-Guo Zhou, Yong-Yuan Guan, Xiao-Fei Lv, Ming-Ming Ma
Vascular smooth muscle-specific LRRC8A knockout ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting the WNK1/FOXO3a/MMP signaling pathway. Acta pharmacologica Sinica 45 (9) (2024)
Ya-Qi Yang, Yi-Jun Liu, Wen-Xuan Qiao, Wei Jin, Shun-Wei Zhu, Yu-Xi Yan, Qiong Luo, Qiang Xu
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren's syndrome in mice by promoting TEC kinase degradation. Acta pharmacologica Sinica 45 (9) (2024)
Chun-Yan Duan, Yue Li, Hao-Yu Zhi, Yao Tian, Zheng-Yun Huang, Su-Ping Chen, Yang Zhang, Qing Liu, Liang Zhou, Xiao-Gang Jiang, Kifayat Ullah, Qing Guo, Zhao-Hui Liu, Ying Xu, Jun-Hai Han, Jiajie Hou, Darran P O'Connor, Guoqiang Xu
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1. Acta pharmacologica Sinica 45 (9) (2024)
Ya-Qi Yang, Yi-Jun Liu, Wen-Xuan Qiao, Wei Jin, Shun-Wei Zhu, Yu-Xi Yan, Qiong Luo, Qiang Xu
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren's syndrome in mice by promoting TEC kinase degradation. Acta pharmacologica Sinica 45 (9) (2024)
Zhi-Hua Zheng, Jiao-Jiao Wang, Jiu-Guo Lin, Wei-le Ye, Jia-Mi Zou, Li-Yin Liang, Ping-Lian Yang, Wan-Lu Qiu, Yuan-Yuan Li, Si-Jia Yang, Man Zhao, Qing Zhou, Cheng-Zhi Li, Min Li, Zhuo-Ming Li, Dong-Mei Zhang, Pei-Qing Liu, Zhi-Ping Liu
Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol. Acta pharmacologica Sinica 45 (9) (2024)
Chun-Yan Duan, Yue Li, Hao-Yu Zhi, Yao Tian, Zheng-Yun Huang, Su-Ping Chen, Yang Zhang, Qing Liu, Liang Zhou, Xiao-Gang Jiang, Kifayat Ullah, Qing Guo, Zhao-Hui Liu, Ying Xu, Jun-Hai Han, Jiajie Hou, Darran P O'Connor, Guoqiang Xu
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1. Acta pharmacologica Sinica 45 (9) (2024)
Zhi-Hua Zheng, Jiao-Jiao Wang, Jiu-Guo Lin, Wei-le Ye, Jia-Mi Zou, Li-Yin Liang, Ping-Lian Yang, Wan-Lu Qiu, Yuan-Yuan Li, Si-Jia Yang, Man Zhao, Qing Zhou, Cheng-Zhi Li, Min Li, Zhuo-Ming Li, Dong-Mei Zhang, Pei-Qing Liu, Zhi-Ping Liu
Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol. Acta pharmacologica Sinica 45 (9) (2024)
Hua-Shan Gong, Jing-Pei Pan, Fei Guo, Mei-Mei Wu, Li Dong, Yang Li, Wei-Fang Rong
Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice. Acta pharmacologica Sinica 45 (9) (2024)
Xin-Yue Wang, Xin Chai, Lu-Hu Shan, Xiao-Hong Xu, Lei Xu, Ting-Jun Hou, Hui-Yong Sun, Dan Li
A potent new-scaffold androgen receptor antagonist discovered on the basis of a MIEC-SVM model. Acta pharmacologica Sinica 45 (9) (2024)
Ya-Qi Yang, Yi-Jun Liu, Wen-Xuan Qiao, Wei Jin, Shun-Wei Zhu, Yu-Xi Yan, Qiong Luo, Qiang Xu
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren's syndrome in mice by promoting TEC kinase degradation. Acta pharmacologica Sinica 45 (9) (2024)
Xi-Shan Wu, Xiao-Yu Luo, Cheng-Chang Li, Xiao-Fan Zhao, Cheng Zhang, Xiao-Shan Chen, Zhi-Fang Lu, Tong Wu, Hao-Nan Yu, Chao Peng, Qing-Qing Hu, Hui Shen, Yong Xu, Yan Zhang
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer. Acta pharmacologica Sinica 45 (9) (2024)
Sen-Lin Li, Hong Zhou, Jia Liu, Jian Yang, Li Jiang, Hui-Min Yuan, Meng-Heng Wang, Ke-Shan Yang, Ming Xiang
Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder. Acta pharmacologica Sinica 45 (9) (2024)
Xin-Yue Wang, Xin Chai, Lu-Hu Shan, Xiao-Hong Xu, Lei Xu, Ting-Jun Hou, Hui-Yong Sun, Dan Li
A potent new-scaffold androgen receptor antagonist discovered on the basis of a MIEC-SVM model. Acta pharmacologica Sinica 45 (9) (2024)
Chun-Yu Hou, Pan Lv, Hong-Feng Yuan, Li-Na Zhao, Yu-Fei Wang, Hui-Hui Zhang, Guang Yang, Xiao-Dong Zhang
Bevacizumab induces ferroptosis and enhances CD8 + T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9. Acta pharmacologica Sinica 45 (9) (2024)
Xiu-Chun Li, Xia-Yan Zhu, Yang-Yue Wang, Shuo-Lan Tong, Zhi-Li Chen, Zi-Yi Lu, Jian-Hao Zhang, Lan-Lan Song, Xing-Hong Wang, Chi Zhang, Yi-Han Sun, Chu-Yue Zhong, Li-Huang Su, Liang-Xing Wang, Xiao-Ying Huang
Canagliflozin alleviates pulmonary hypertension by activating PPARγ and inhibiting its S225 phosphorylation. Acta pharmacologica Sinica 45 (9) (2024)
Sen-Lin Li, Hong Zhou, Jia Liu, Jian Yang, Li Jiang, Hui-Min Yuan, Meng-Heng Wang, Ke-Shan Yang, Ming Xiang
Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder. Acta pharmacologica Sinica 45 (9) (2024)
Xi-Shan Wu, Xiao-Yu Luo, Cheng-Chang Li, Xiao-Fan Zhao, Cheng Zhang, Xiao-Shan Chen, Zhi-Fang Lu, Tong Wu, Hao-Nan Yu, Chao Peng, Qing-Qing Hu, Hui Shen, Yong Xu, Yan Zhang
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer. Acta pharmacologica Sinica 45 (9) (2024)
Jian-Hui Xu, Tian-Hui He, Nan-Ping Wang, Wen-Min Gao, Yong-Jing Cheng, Qiao-Feng Ji, Si-Hao Wu, Yan-Lin Wei, Yu Tang, Wen Z Yang, Jie Zhang
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E 2 in the lateral parabrachial nucleus of male rats. Acta pharmacologica Sinica 45 (9) (2024)
Xin-Yue Wang, Xin Chai, Lu-Hu Shan, Xiao-Hong Xu, Lei Xu, Ting-Jun Hou, Hui-Yong Sun, Dan Li
A potent new-scaffold androgen receptor antagonist discovered on the basis of a MIEC-SVM model. Acta pharmacologica Sinica 45 (9) (2024)
Mo-Ting Liu, Yao Zhang, Cai-Gui Xiang, Tao Yang, Xiao-Han Wang, Qiu-Kai Lu, Hui-Min Lu, Chen Fan, Chun-Lan Feng, Xiao-Qian Yang, Duo-Wu Zou, Heng Li, Wei Tang
Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages. Acta pharmacologica Sinica 45 (9) (2024)
Xiao-Lu Jiang, Zu-Bin Zhang, Chen-Xi Feng, Chen-Jie Lin, Hui Yang, Lan-Lan Tan, Xin Ding, Li-Xiao Xu, Gen Li, Tao Pan, Zheng-Hong Qin, Bin Sun, Xing Feng, Mei Li
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy. Acta pharmacologica Sinica 45 (9) (2024)
Xiu-Chun Li, Xia-Yan Zhu, Yang-Yue Wang, Shuo-Lan Tong, Zhi-Li Chen, Zi-Yi Lu, Jian-Hao Zhang, Lan-Lan Song, Xing-Hong Wang, Chi Zhang, Yi-Han Sun, Chu-Yue Zhong, Li-Huang Su, Liang-Xing Wang, Xiao-Ying Huang
Canagliflozin alleviates pulmonary hypertension by activating PPARγ and inhibiting its S225 phosphorylation. Acta pharmacologica Sinica 45 (9) (2024)
Rui-Xin Sun, Yi-Fan Liu, Yan-Sha Sun, Min Zhou, Yi Wang, Bi-Zhi Shi, Hua Jiang, Zong-Hai Li
GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma. Acta pharmacologica Sinica 45 (9) (2024)
Xi-Shan Wu, Xiao-Yu Luo, Cheng-Chang Li, Xiao-Fan Zhao, Cheng Zhang, Xiao-Shan Chen, Zhi-Fang Lu, Tong Wu, Hao-Nan Yu, Chao Peng, Qing-Qing Hu, Hui Shen, Yong Xu, Yan Zhang
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer. Acta pharmacologica Sinica 45 (9) (2024)
Jian-Hui Xu, Tian-Hui He, Nan-Ping Wang, Wen-Min Gao, Yong-Jing Cheng, Qiao-Feng Ji, Si-Hao Wu, Yan-Lin Wei, Yu Tang, Wen Z Yang, Jie Zhang
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E 2 in the lateral parabrachial nucleus of male rats. Acta pharmacologica Sinica 45 (9) (2024)
Ana Beatriz Santos, Andreia Carona, Miren Ettcheto, Antoni Camins, Amílcar Falcão, Ana Fortuna, Joana Bicker
Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis. Acta pharmacologica Sinica 45 (9) (2024)
Sen-Lin Li, Hong Zhou, Jia Liu, Jian Yang, Li Jiang, Hui-Min Yuan, Meng-Heng Wang, Ke-Shan Yang, Ming Xiang
Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder. Acta pharmacologica Sinica 45 (9) (2024)
Xiao-Lu Jiang, Zu-Bin Zhang, Chen-Xi Feng, Chen-Jie Lin, Hui Yang, Lan-Lan Tan, Xin Ding, Li-Xiao Xu, Gen Li, Tao Pan, Zheng-Hong Qin, Bin Sun, Xing Feng, Mei Li
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy. Acta pharmacologica Sinica 45 (9) (2024)
Rui-Xin Sun, Yi-Fan Liu, Yan-Sha Sun, Min Zhou, Yi Wang, Bi-Zhi Shi, Hua Jiang, Zong-Hai Li
GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma. Acta pharmacologica Sinica 45 (9) (2024)
Chun-Yan Duan, Yue Li, Hao-Yu Zhi, Yao Tian, Zheng-Yun Huang, Su-Ping Chen, Yang Zhang, Qing Liu, Liang Zhou, Xiao-Gang Jiang, Kifayat Ullah, Qing Guo, Zhao-Hui Liu, Ying Xu, Jun-Hai Han, Jiajie Hou, Darran P O'Connor, Guoqiang Xu
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1. Acta pharmacologica Sinica 45 (9) (2024)
Chun-Yu Hou, Pan Lv, Hong-Feng Yuan, Li-Na Zhao, Yu-Fei Wang, Hui-Hui Zhang, Guang Yang, Xiao-Dong Zhang
Bevacizumab induces ferroptosis and enhances CD8 + T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9. Acta pharmacologica Sinica 45 (9) (2024)
Jian-Hui Xu, Tian-Hui He, Nan-Ping Wang, Wen-Min Gao, Yong-Jing Cheng, Qiao-Feng Ji, Si-Hao Wu, Yan-Lin Wei, Yu Tang, Wen Z Yang, Jie Zhang
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E 2 in the lateral parabrachial nucleus of male rats. Acta pharmacologica Sinica 45 (9) (2024)
Hua-Shan Gong, Jing-Pei Pan, Fei Guo, Mei-Mei Wu, Li Dong, Yang Li, Wei-Fang Rong
Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice. Acta pharmacologica Sinica 45 (9) (2024)
Mo-Ting Liu, Yao Zhang, Cai-Gui Xiang, Tao Yang, Xiao-Han Wang, Qiu-Kai Lu, Hui-Min Lu, Chen Fan, Chun-Lan Feng, Xiao-Qian Yang, Duo-Wu Zou, Heng Li, Wei Tang
Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages. Acta pharmacologica Sinica 45 (9) (2024)
Chun-Yu Hou, Pan Lv, Hong-Feng Yuan, Li-Na Zhao, Yu-Fei Wang, Hui-Hui Zhang, Guang Yang, Xiao-Dong Zhang
Bevacizumab induces ferroptosis and enhances CD8 + T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9. Acta pharmacologica Sinica 45 (9) (2024)
Xiao-Lu Jiang, Zu-Bin Zhang, Chen-Xi Feng, Chen-Jie Lin, Hui Yang, Lan-Lan Tan, Xin Ding, Li-Xiao Xu, Gen Li, Tao Pan, Zheng-Hong Qin, Bin Sun, Xing Feng, Mei Li
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy. Acta pharmacologica Sinica 45 (9) (2024)
Rui-Xin Sun, Yi-Fan Liu, Yan-Sha Sun, Min Zhou, Yi Wang, Bi-Zhi Shi, Hua Jiang, Zong-Hai Li
GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma. Acta pharmacologica Sinica 45 (9) (2024)
Ze-Ka Chen, Yuan-Yuan Liu, Ji-Chuan Zhou, Gui-Hai Chen, Chun-Feng Liu, Wei-Min Qu, Zhi-Li Huang
Insomnia-related rodent models in drug discovery. Acta pharmacologica Sinica 45 (9) (2024)
Hua-Shan Gong, Jing-Pei Pan, Fei Guo, Mei-Mei Wu, Li Dong, Yang Li, Wei-Fang Rong
Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice. Acta pharmacologica Sinica 45 (9) (2024)
Ana Beatriz Santos, Andreia Carona, Miren Ettcheto, Antoni Camins, Amílcar Falcão, Ana Fortuna, Joana Bicker
Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis. Acta pharmacologica Sinica 45 (9) (2024)
Ze-Ka Chen, Yuan-Yuan Liu, Ji-Chuan Zhou, Gui-Hai Chen, Chun-Feng Liu, Wei-Min Qu, Zhi-Li Huang
Insomnia-related rodent models in drug discovery. Acta pharmacologica Sinica 45 (9) (2024)