Toxicological sciences : an official journal of the Society of Toxicology

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Publications

volume 201, number 1, 2024

Hao Xu, Xiaoyu Mao, Siling Zhang, Jie Ren, Shanwen Jiang, Lijuan Cai, Xiaomin Miao, Yixi Tao, Chao Peng, Mengzhu Lv, Yun Li
Perfluorooctanoic acid triggers premature ovarian insufficiency by impairing NAD+ synthesis and mitochondrial function in adult zebrafish. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Jennifer B Faske, Meagan B Myers, Matthew S Bryant, Xiaobo He, Florence McLellen, Todd Bourcier, Barbara L Parsons
CarcSeq detection of lorcaserin-induced clonal expansion of Pik3ca H1047R mutants in rat mammary tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Arlet Hernandez, Jenna Hedlich-Dwyer, Saddam Hussain, Hailey Levi, Manoj Sonavane, Tetsuya Suzuki, Hiroyuki Kamiya, Natalie R Gassman
Acute exposure to dihydroxyacetone promotes genotoxicity and chromosomal instability in lung, cardiac, and liver cell models. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Matthew W Day, Coreen Daley, Yifan Wu, Maduomethaa Pathmaraj, Marc-André Verner, Élyse Caron-Beaudoin
Altered oxidative stress and antioxidant biomarkers concentrations in pregnant individuals exposed to oil and gas sites in Northeastern British Columbia. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Joseph H Lucas, Qixin Wang, Jiries Meehan-Atrash, Cortney Pang, Irfan Rahman
Developmental PFOS exposure alters lung inflammation and barrier integrity in juvenile mice. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Arlet Hernandez, Jenna Hedlich-Dwyer, Saddam Hussain, Hailey Levi, Manoj Sonavane, Tetsuya Suzuki, Hiroyuki Kamiya, Natalie R Gassman
Acute exposure to dihydroxyacetone promotes genotoxicity and chromosomal instability in lung, cardiac, and liver cell models. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Mark C Daley, Marjory Moreau, Peter Bronk, Jeffrey Fisher, Celinda M Kofron, Ulrike Mende, Patrick McMullen, Bum-Rak Choi, Kareen Coulombe
In vitro to in vivo extrapolation from 3D hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrhythmia risk assessment. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Haiyan Lu, Sandra S Wise, Rachel M Speer, Tayler J Croom-Perez, Jennifer H Toyoda, Idoia Meaza, Aggie Williams, John Pierce Wise, J Calvin Kouokam, Jamie Young Wise, Gary W Hoyle, Cairong Zhu, Abdul-Mehdi Ali, John Pierce Wise
Acute particulate hexavalent chromium exposure induces DNA double-strand breaks and activates homologous recombination repair in rat lung tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Arlet Hernandez, Jenna Hedlich-Dwyer, Saddam Hussain, Hailey Levi, Manoj Sonavane, Tetsuya Suzuki, Hiroyuki Kamiya, Natalie R Gassman
Acute exposure to dihydroxyacetone promotes genotoxicity and chromosomal instability in lung, cardiac, and liver cell models. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Haiyan Lu, Sandra S Wise, Rachel M Speer, Tayler J Croom-Perez, Jennifer H Toyoda, Idoia Meaza, Aggie Williams, John Pierce Wise, J Calvin Kouokam, Jamie Young Wise, Gary W Hoyle, Cairong Zhu, Abdul-Mehdi Ali, John Pierce Wise
Acute particulate hexavalent chromium exposure induces DNA double-strand breaks and activates homologous recombination repair in rat lung tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Mark C Daley, Marjory Moreau, Peter Bronk, Jeffrey Fisher, Celinda M Kofron, Ulrike Mende, Patrick McMullen, Bum-Rak Choi, Kareen Coulombe
In vitro to in vivo extrapolation from 3D hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrhythmia risk assessment. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Mark C Daley, Marjory Moreau, Peter Bronk, Jeffrey Fisher, Celinda M Kofron, Ulrike Mende, Patrick McMullen, Bum-Rak Choi, Kareen Coulombe
In vitro to in vivo extrapolation from 3D hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrhythmia risk assessment. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Endia J Fletcher, Winter S Stubblefield, Justin Huff, Ramsés Santacruz-Márquez, Mary Laws, Emily Brehm, Jodi A Flaws
Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Demetrius McAtee, Ahmed Abdelmoneim
Effects of developmental exposure to arsenic species on behavioral stress responses in larval zebrafish and implications for stress-related disorders. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Joseph H Lucas, Qixin Wang, Jiries Meehan-Atrash, Cortney Pang, Irfan Rahman
Developmental PFOS exposure alters lung inflammation and barrier integrity in juvenile mice. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Endia J Fletcher, Winter S Stubblefield, Justin Huff, Ramsés Santacruz-Márquez, Mary Laws, Emily Brehm, Jodi A Flaws
Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Ley Cody Smith, Elena Abramova, Kinal Vayas, Jessica Rodriguez, Benjamin Gelfand-Titiyevksiy, Troy A Roepke, Jeffrey D Laskin, Andrew J Gow, Debra L Laskin
Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Mark C Daley, Marjory Moreau, Peter Bronk, Jeffrey Fisher, Celinda M Kofron, Ulrike Mende, Patrick McMullen, Bum-Rak Choi, Kareen Coulombe
In vitro to in vivo extrapolation from 3D hiPSC-derived cardiac microtissues and physiologically based pharmacokinetic modeling to inform next-generation arrhythmia risk assessment. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Joseph H Lucas, Qixin Wang, Jiries Meehan-Atrash, Cortney Pang, Irfan Rahman
Developmental PFOS exposure alters lung inflammation and barrier integrity in juvenile mice. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Matthew W Day, Coreen Daley, Yifan Wu, Maduomethaa Pathmaraj, Marc-André Verner, Élyse Caron-Beaudoin
Altered oxidative stress and antioxidant biomarkers concentrations in pregnant individuals exposed to oil and gas sites in Northeastern British Columbia. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Yueshan Zhao, Ji Youn Park, Da Yang, Min Zhang
A computational framework to in silico screen for drug-induced hepatocellular toxicity. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Jennifer B Faske, Meagan B Myers, Matthew S Bryant, Xiaobo He, Florence McLellen, Todd Bourcier, Barbara L Parsons
CarcSeq detection of lorcaserin-induced clonal expansion of Pik3ca H1047R mutants in rat mammary tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Endia J Fletcher, Winter S Stubblefield, Justin Huff, Ramsés Santacruz-Márquez, Mary Laws, Emily Brehm, Jodi A Flaws
Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Ley Cody Smith, Elena Abramova, Kinal Vayas, Jessica Rodriguez, Benjamin Gelfand-Titiyevksiy, Troy A Roepke, Jeffrey D Laskin, Andrew J Gow, Debra L Laskin
Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Yueshan Zhao, Ji Youn Park, Da Yang, Min Zhang
A computational framework to in silico screen for drug-induced hepatocellular toxicity. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Ley Cody Smith, Elena Abramova, Kinal Vayas, Jessica Rodriguez, Benjamin Gelfand-Titiyevksiy, Troy A Roepke, Jeffrey D Laskin, Andrew J Gow, Debra L Laskin
Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Arlet Hernandez, Jenna Hedlich-Dwyer, Saddam Hussain, Hailey Levi, Manoj Sonavane, Tetsuya Suzuki, Hiroyuki Kamiya, Natalie R Gassman
Acute exposure to dihydroxyacetone promotes genotoxicity and chromosomal instability in lung, cardiac, and liver cell models. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Yueshan Zhao, Ji Youn Park, Da Yang, Min Zhang
A computational framework to in silico screen for drug-induced hepatocellular toxicity. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Allison M Narizzano, Emily May Lent, Andrew G East, Meredith E Bohannon, Michael J Quinn
Threshold for increased liver weight is protective of other effects in Peromyscus exposed to PFNA. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Yueshan Zhao, Ji Youn Park, Da Yang, Min Zhang
A computational framework to in silico screen for drug-induced hepatocellular toxicity. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Jennifer B Faske, Meagan B Myers, Matthew S Bryant, Xiaobo He, Florence McLellen, Todd Bourcier, Barbara L Parsons
CarcSeq detection of lorcaserin-induced clonal expansion of Pik3ca H1047R mutants in rat mammary tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Haiyan Lu, Sandra S Wise, Rachel M Speer, Tayler J Croom-Perez, Jennifer H Toyoda, Idoia Meaza, Aggie Williams, John Pierce Wise, J Calvin Kouokam, Jamie Young Wise, Gary W Hoyle, Cairong Zhu, Abdul-Mehdi Ali, John Pierce Wise
Acute particulate hexavalent chromium exposure induces DNA double-strand breaks and activates homologous recombination repair in rat lung tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Joseph H Lucas, Qixin Wang, Jiries Meehan-Atrash, Cortney Pang, Irfan Rahman
Developmental PFOS exposure alters lung inflammation and barrier integrity in juvenile mice. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Endia J Fletcher, Winter S Stubblefield, Justin Huff, Ramsés Santacruz-Márquez, Mary Laws, Emily Brehm, Jodi A Flaws
Prenatal exposure to an environmentally relevant phthalate mixture alters serum cytokine levels and inflammatory markers in the F1 mouse ovary. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Matthew W Day, Coreen Daley, Yifan Wu, Maduomethaa Pathmaraj, Marc-André Verner, Élyse Caron-Beaudoin
Altered oxidative stress and antioxidant biomarkers concentrations in pregnant individuals exposed to oil and gas sites in Northeastern British Columbia. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)
Haiyan Lu, Sandra S Wise, Rachel M Speer, Tayler J Croom-Perez, Jennifer H Toyoda, Idoia Meaza, Aggie Williams, John Pierce Wise, J Calvin Kouokam, Jamie Young Wise, Gary W Hoyle, Cairong Zhu, Abdul-Mehdi Ali, John Pierce Wise
Acute particulate hexavalent chromium exposure induces DNA double-strand breaks and activates homologous recombination repair in rat lung tissue. Toxicological sciences : an official journal of the Society of Toxicology 201 (1) (2024)

volume 200, number 2, 2024

Roman Mezencev, Madison Feshuk, Lori Kolaczkowski, Geoffrey Colin Peterson, Q Jay Zhao, Sean Watford, J Andre Weaver
The association between histopathologic effects and liver weight changes induced in mice and rats by chemical exposures: an analysis of the data from Toxicity Reference Database (ToxRefDB). Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Nelly Buron, Mathieu Porceddu, Roxane Loyant, Cécile Martel, Julien A Allard, Bernard Fromenty, Annie Borgne-Sanchez
Drug-induced impairment of mitochondrial fatty acid oxidation and steatosis: assessment of causal relationship with 45 pharmaceuticals. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Alicia Arredondo Eve, Elif Tunc, Dhruv Mehta, Jin Young Yoo, Huriye Erbak Yilmaz, Sadık Volkan Emren, Filiz Akyıldız Akçay, Zeynep Madak Erdogan
PFAS and their association with the increased risk of cardiovascular disease in postmenopausal women. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Tiffany Cho, Anthony Hayes, Jeffrey T Henderson, Jack Uetrecht
The use of PD-1 functional knockout rats to study idiosyncratic adverse reactions to nevirapine. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Jared Radbel, Jaclynn A Meshanni, Kinal N Vayas, Oahn Le-Hoang, Elena Abramova, Peihong Zhou, Laurie B Joseph, Jeffrey D Laskin, Andrew J Gow, Debra L Laskin
Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of nonpneumonic endotoxemia. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Michael G Morash, Morgan W Kirzinger, John C Achenbach, Ananda B Venkatachalam, Jessica Nixon, Susanne Penny, Joëlle Pinsonnault Cooper, Deborah E Ratzlaff, Cindy L A Woodland, Lee D Ellis
Comparative toxicological assessment of 2 bisphenols using a systems approach: evaluation of the behavioral and transcriptomic responses of Danio rerio to bisphenol A and tetrabromobisphenol A. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Manasi Kotulkar, Diego Paine Cabrera, Dakota R Robarts, Udayan Apte
Regulation of hepatic xenosensor function by HNF4alpha. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Chelin Jamie Hu, Marcus A Garcia, Alexander Nihart, Rui Liu, Lei Yin, Natalie Adolphi, Daniel F Gallego, Huining Kang, Matthew J Campen, Xiaozhong Yu
Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Ena Vujic, Stephen S Ferguson, Kim L R Brouwer
Effects of PFAS on human liver transporters: implications for health outcomes. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Manasi Kotulkar, Diego Paine Cabrera, Dakota R Robarts, Udayan Apte
Regulation of hepatic xenosensor function by HNF4alpha. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Mark A Carfagna, Cm Sabbir Ahmed, Susan Butler, Tamio Fukushima, William Houser, Nikolai K Jensen, Brianna Paisley, Stephanie Leuenroth-Quinn, Kevin M Snyder, Saurabh Vispute, Wenxian Wang, Md Yousuf Ali
Cross study analyses of SEND data: toxicity profile classification. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Tiffany Cho, Anthony Hayes, Jeffrey T Henderson, Jack Uetrecht
The use of PD-1 functional knockout rats to study idiosyncratic adverse reactions to nevirapine. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Jared Radbel, Jaclynn A Meshanni, Kinal N Vayas, Oahn Le-Hoang, Elena Abramova, Peihong Zhou, Laurie B Joseph, Jeffrey D Laskin, Andrew J Gow, Debra L Laskin
Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of nonpneumonic endotoxemia. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)
Mark A Carfagna, Cm Sabbir Ahmed, Susan Butler, Tamio Fukushima, William Houser, Nikolai K Jensen, Brianna Paisley, Stephanie Leuenroth-Quinn, Kevin M Snyder, Saurabh Vispute, Wenxian Wang, Md Yousuf Ali
Cross study analyses of SEND data: toxicity profile classification. Toxicological sciences : an official journal of the Society of Toxicology 200 (2) (2024)