Adrian R Krainer

Publication Activity (10 Years)

Years Active: 2022-2024
Publications (10 Years): 33

Top Topics

Cystic Fibrosis

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Nature genetics

Nucleic acid therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics (2024)
Danilo Segovia, Dexter W Adams, Nickolas Hoffman, Polona Safaric Tepes, Tse-Luen Wee, Paolo Cifani, Leemor Joshua-Tor, Adrian R Krainer
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics 56 (7) (2024)
Danilo Segovia, Dexter W Adams, Nickolas Hoffman, Polona Safaric Tepes, Tse-Luen Wee, Paolo Cifani, Leemor Joshua-Tor, Adrian R Krainer
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics 56 (7) (2024)
Ledong Wan, Alexander J Kral, Dillon Voss, Balázs Schäfer, Kavitha Sudheendran, Mathias Danielsen, Marvin H Caruthers, Adrian R Krainer
Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids. Nucleic acid therapeutics (2024)
Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Danilo Segovia, Dexter W Adams, Nickolas Hoffman, Polona Safaric Tepes, Tse-Luen Wee, Paolo Cifani, Leemor Joshua-Tor, Adrian R Krainer
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics (2024)
Danilo Segovia, Dexter W Adams, Nickolas Hoffman, Polona Safaric Tepes, Tse-Luen Wee, Paolo Cifani, Leemor Joshua-Tor, Adrian R Krainer
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Ledong Wan, Alexander J Kral, Dillon Voss, Balázs Schäfer, Kavitha Sudheendran, Mathias Danielsen, Marvin H Caruthers, Adrian R Krainer
Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids. Nucleic acid therapeutics (2024)
Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Ledong Wan, Alexander J Kral, Dillon Voss, Balázs Schäfer, Kavitha Sudheendran, Mathias Danielsen, Marvin H Caruthers, Adrian R Krainer
Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids. Nucleic acid therapeutics 34 (4) (2024)
Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Yuma Ishigami, Mandy S Wong, Carlos Martí-Gómez, Andalus Ayaz, Mahdi Kooshkbaghi, Sonya M Hanson, David M McCandlish, Adrian R Krainer, Justin B Kinney
Specificity, synergy, and mechanisms of splice-modifying drugs. Nature communications 15 (1) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics 56 (7) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics (2024)
Danilo Segovia, Dexter W Adams, Nickolas Hoffman, Polona Safaric Tepes, Tse-Luen Wee, Paolo Cifani, Leemor Joshua-Tor, Adrian R Krainer
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America 121 (21) (2024)
Diogo Maia-Silva, Patrick J Cunniff, Allison C Schier, Damianos Skopelitis, Marygrace C Trousdell, Philip Moresco, Yuan Gao, Vahag Kechejian, Xue-Yan He, Yunus Sahin, Ledong Wan, Aktan Alpsoy, Jynelle Liverpool, Adrian R Krainer, Mikala Egeblad, David L Spector, Douglas T Fearon, Camila Oresco Dos Santos, Dylan J Taatjes, Christopher R Vakoc
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature genetics 56 (7) (2024)
Ledong Wan, Alexander J Kral, Dillon Voss, Balázs Schäfer, Kavitha Sudheendran, Mathias Danielsen, Marvin H Caruthers, Adrian R Krainer
Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids. Nucleic acid therapeutics 34 (4) (2024)
Ledong Wan, Kuang-Ting Lin, Mohammad Alinoor Rahman, Yuma Ishigami, Zhikai Wang, Mads A Jensen, John E Wilkinson, Youngkyu Park, David A Tuveson, Adrian R Krainer
Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer. Cancer discovery (2023)
Young Jin Kim, Adrian R Krainer
Antisense Oligonucleotide Therapeutics for Cystic Fibrosis: Recent Developments and Perspectives. Molecules and cells 46 (1) (2023)
Young Jin Kim, Adrian R Krainer
Antisense Oligonucleotide Therapeutics for Cystic Fibrosis: Recent Developments and Perspectives. Molecules and cells 46 (1) (2023)
Amina Jbara, Kuan-Ting Lin, Chani Stossel, Zahava Siegfried, Haya Shqerat, Adi Amar-Schwartz, Ela Elyada, Maxim Mogilevsky, Maria Raitses-Gurevich, Jared L Johnson, Tomer M Yaron, Ofek Ovadia, Gun Ho Jang, Miri Danan Gotthold, Lewis C Cantley, Erez Y Levanon, Steven Gallinger, Adrian R Krainer, Talia Golan, Rotem Karni
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer. Nature (2023)
Young Jin Kim, Adrian R Krainer
Antisense Oligonucleotide Therapeutics for Cystic Fibrosis: Recent Developments and Perspectives. Molecules and cells 46 (1) (2023)
Ledong Wan, Kuang-Ting Lin, Mohammad Alinoor Rahman, Yuma Ishigami, Zhikai Wang, Mads A Jensen, John E Wilkinson, Youngkyu Park, David A Tuveson, Adrian R Krainer
Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer. Cancer discovery (2023)
Qian Zhang, Lucia Yang, Ying Hsiu Liu, John E Wilkinson, Adrian R Krainer
Antisense oligonucleotide therapy for H3.3K27M diffuse midline glioma. Science translational medicine 15 (691) (2023)
Young Jin Kim, Tomoki Nomakuchi, Foteini Papaleonidopoulou, Lucia Yang, Qian Zhang, Adrian R Krainer
Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy. Nature communications 13 (1) (2022)
Young Jin Kim, Nicole Sivetz, Jessica Layne, Dillon M Voss, Lucia Yang, Qian Zhang, Adrian R Krainer
Exon-skipping antisense oligonucleotides for cystic fibrosis therapy. Proceedings of the National Academy of Sciences of the United States of America 119 (3) (2022)
Juannan Zhou, Mandy S Wong, Wei-Chia Chen, Adrian R Krainer, Justin B Kinney, David M McCandlish
Higher-order epistasis and phenotypic prediction. Proceedings of the National Academy of Sciences of the United States of America 119 (39) (2022)