Akimitsu Okamoto

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Venues

Journal of the American Chemical Society

Chembiochem : a European journal of chemical biology

Journal of materials chemistry. B

Nature chemical biology

The University of Tokyo

Kyoto University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Tokyo Jan 15 2012

Japan

Professor :: Research Center for Advanced Science and Technology

RIKEN Apr 01 2006 - Jan 14 2012

Japan

Unit Leader

Kyoto University Apr 01 1999 - Mar 31 2006

Japan

Assistant Professor :: Synthetic Chemistry and Biological Chemistry

MIT Apr 01 1998 - Mar 31 1999

United States

PD :: Chemistry

Education History

Kyoto University Apr 01 1995 - Mar 31 1998

Japan

PHD :: Synthetic Chemistry and Biological Chemistry

Publications

Kunihiko Morihiro, Shunto Morita, Naoki Harada, Manami Baba, Jongmin Yum, Mitsuru Naito, Kanjiro Miyata, Genta Nagae, Akimitsu Okamoto
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality. Journal of the American Chemical Society 146 (2) (2024)
Kenjyo Miyauchi, Satoshi Kimura, Naho Akiyama, Kazuki Inoue, Kensuke Ishiguro, Thien-Son Vu, Veerasak Srisuknimit, Kenta Koyama, Gosuke Hayashi, Akiko Soma, Asuteka Nagao, Mikako Shirouzu, Akimitsu Okamoto, Matthew Kaden Waldor, Tsutomu Suzuki
A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis. Nature chemical biology (2024)
Xueli Ren, Hironori Tsuji, Takahiko Uchino, Izumi Kono, Takashi Isoshima, Akimitsu Okamoto, Noriyuki Nagaoka, Toshifumi Ozaki, Akihiro Matsukawa, Hideyuki Miyatake, Yoshihiro Ito
An osteoinductive surface by adhesive bone morphogenetic protein-2 prepared using the bioorthogonal approach for tight binding of titanium with bone. Journal of materials chemistry. B 12 (12) (2024)
Kunihiko Morihiro, Shunto Morita, Naoki Harada, Manami Baba, Jongmin Yum, Mitsuru Naito, Kanjiro Miyata, Genta Nagae, Akimitsu Okamoto
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality. Journal of the American Chemical Society 146 (2) (2024)
Kunihiko Morihiro, Shunto Morita, Naoki Harada, Manami Baba, Jongmin Yum, Mitsuru Naito, Kanjiro Miyata, Genta Nagae, Akimitsu Okamoto
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality. Journal of the American Chemical Society (2024)
Kunihiko Morihiro, Shunto Morita, Naoki Harada, Manami Baba, Jongmin Yum, Mitsuru Naito, Kanjiro Miyata, Genta Nagae, Akimitsu Okamoto
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality. Journal of the American Chemical Society 146 (2) (2024)
Xueli Ren, Hironori Tsuji, Takahiko Uchino, Izumi Kono, Takashi Isoshima, Akimitsu Okamoto, Noriyuki Nagaoka, Toshifumi Ozaki, Akihiro Matsukawa, Hideyuki Miyatake, Yoshihiro Ito
An osteoinductive surface by adhesive bone morphogenetic protein-2 prepared using the bioorthogonal approach for tight binding of titanium with bone. Journal of materials chemistry. B (2024)
Minako Narita, Ai Kohata, Taiichi Kageyama, Honoka Watanabe, Kohsuke Aikawa, Daisuke Kawaguchi, Kunihiko Morihiro, Akimitsu Okamoto, Takashi Okazoe
Fluorocarbon-DNA Conjugates for Enhanced Cellular Delivery: Formation of a Densely Packed DNA Nano-Assembly. Chembiochem : a European journal of chemical biology (2024)
Xueli Ren, Hironori Tsuji, Takahiko Uchino, Izumi Kono, Takashi Isoshima, Akimitsu Okamoto, Noriyuki Nagaoka, Toshifumi Ozaki, Akihiro Matsukawa, Hideyuki Miyatake, Yoshihiro Ito
An osteoinductive surface by adhesive bone morphogenetic protein-2 prepared using the bioorthogonal approach for tight binding of titanium with bone. Journal of materials chemistry. B 12 (12) (2024)
Sae Suzuki, Yuya Nakajima, Naoki Kamo, Akihisa Osakabe, Akimitsu Okamoto, Gosuke Hayashi, Hiroshi Murakami
Thiocholine-Mediated One-Pot Peptide Ligation and Desulfurization. Molecules (Basel, Switzerland) 28 (9) (2023)
Masako Takatsu, Kunihiko Morihiro, Honoka Watanabe, Mizue Yuki, Takara Hattori, Kentaro Noi, Kohsuke Aikawa, Keiichi Noguchi, Masafumi Yohda, Takashi Okazoe, Akimitsu Okamoto
Cellular Penetration and Intracellular Dynamics of Perfluorocarbon-Conjugated DNA/RNA as a Potential Means of Conditional Nucleic Acid Delivery. ACS chemical biology (2023)
Takafumi Furuhata, Phebee Angeline Devadasan Racheal, Iori Murayama, Usano Toyoda, Akimitsu Okamoto
One-Pot, Photocontrolled Enzymatic Assembly of the Structure-Defined Heterotypic Polyubiquitin Chain. Journal of the American Chemical Society (2023)
Sae Suzuki, Yuya Nakajima, Naoki Kamo, Akihisa Osakabe, Akimitsu Okamoto, Gosuke Hayashi, Hiroshi Murakami
Thiocholine-Mediated One-Pot Peptide Ligation and Desulfurization. Molecules (Basel, Switzerland) 28 (9) (2023)
Kenta Koyama, Gosuke Hayashi, Hiroki Ueda, Satoshi Ota, Genta Nagae, Hiroyuki Aburatani, Akimitsu Okamoto
Base-resolution analysis of 5-hydroxymethylcytidine by selective oxidation and reverse transcription arrest. Organic & biomolecular chemistry 19 (29) (2022)
Takahiro Kosaka, Satoshi Yamaguchi, Shin Izuta, Shinya Yamahira, Yoshikazu Shibasaki, Hiroaki Tateno, Akimitsu Okamoto
Bioorthogonal Photoreactive Surfaces for Single-Cell Analysis of Intercellular Communications. Journal of the American Chemical Society 144 (39) (2022)
Motoyuki Ogata, Gosuke Hayashi, Anri Ichiu, Akimitsu Okamoto
L-DNA-tagged fluorescence in situ hybridization for highly sensitive imaging of RNAs in single cells. Organic & biomolecular chemistry 18 (40) (2022)
Kunihiko Morihiro, Hiraki Osumi, Shunto Morita, Takara Hattori, Manami Baba, Naoki Harada, Riuko Ohashi, Akimitsu Okamoto
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly. Journal of the American Chemical Society 145 (1) (2022)
Kunihiko Morihiro, Hiraki Osumi, Shunto Morita, Takara Hattori, Manami Baba, Naoki Harada, Riuko Ohashi, Akimitsu Okamoto
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly. Journal of the American Chemical Society (2022)
Shinya Yamahira, Ryuji Misawa, Takahiro Kosaka, Mondong Tan, Shin Izuta, Hayato Yamashita, Yuji Heike, Akimitsu Okamoto, Teruyuki Nagamune, Satoshi Yamaguchi
Photoactivatable Materials for Versatile Single-Cell Patterning Based on the Photocaging of Cell-Anchoring Moieties through Lipid Self-Assembly. Journal of the American Chemical Society 144 (29) (2022)
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G Proud, Denis L J Lafontaine, Tsuyoshi Osawa
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors. Nature communications 13 (1) (2022)
Yoshino Akizuki, Mai Morita, Yuki Mori, Ai Kaiho-Soma, Shivani Dixit, Akinori Endo, Marie Shimogawa, Gosuke Hayashi, Mikihiko Naito, Akimitsu Okamoto, Keiji Tanaka, Yasushi Saeki, Fumiaki Ohtake
cIAP1-based degraders induce degradation via branched ubiquitin architectures. Nature chemical biology (2022)
Kunihiko Morihiro, Hiraki Osumi, Shunto Morita, Takara Hattori, Manami Baba, Naoki Harada, Riuko Ohashi, Akimitsu Okamoto
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly. Journal of the American Chemical Society 145 (1) (2022)
Kunihiko Morihiro, Hiraki Osumi, Shunto Morita, Takara Hattori, Manami Baba, Naoki Harada, Riuko Ohashi, Akimitsu Okamoto
Oncolytic Hairpin DNA Pair: Selective Cytotoxic Inducer through MicroRNA-Triggered DNA Self-Assembly. Journal of the American Chemical Society 145 (1) (2022)
Satoshi Yamaguchi, Satoshi Takamori, Kazuho Yamamoto, Akira Ishiwatari, Kosuke Minamihata, Eriko Yamada, Akimitsu Okamoto, Teruyuki Nagamune
Sterically Bulky Caging of Transferrin for Photoactivatable Intracellular Delivery. Bioconjugate chemistry 32 (8) (2021)
Kunihiko Morihiro, Yuya Moriyama, Yui Nemoto, Hiraki Osumi, Akimitsu Okamoto
anti-syn Unnatural Base Pair Enables Alphabet-Expanded DNA Self-Assembly. Journal of the American Chemical Society 143 (35) (2021)
Naoki Kamo, Tomoya Kujirai, Hitoshi Kurumizaka, Hiroshi Murakami, Gosuke Hayashi, Akimitsu Okamoto
Organoruthenium-catalyzed chemical protein synthesis to elucidate the functions of epigenetic modifications on heterochromatin factors. Chemical science 12 (16) (2021)
Ryota Itaya, Wakana Idei, Takashi Nakamura, Tatsuya Nishihara, Ryohsuke Kurihara, Akimitsu Okamoto, Kazuhito Tanabe
Changes of C≡C Triple Bond Vibration that Disclosed Non-Canonical Cytosine Protonation in i-Motif-Forming Oligodeoxynucleotides. ACS omega 6 (47) (2021)
Bjorn Paulson, Yeonhee Shin, Akimitsu Okamoto, Yeon-Mok Oh, Jun Ki Kim, Chan-Gi Pack
Poly(A)+ Sensing of Hybridization-Sensitive Fluorescent Oligonucleotide Probe Characterized by Fluorescence Correlation Methods. International journal of molecular sciences 22 (12) (2021)
Kunihiko Morihiro, Takuro Ishinabe, Masako Takatsu, Hiraki Osumi, Tsuyoshi Osawa, Akimitsu Okamoto
Floxuridine Oligomers Activated under Hypoxic Environment. Journal of the American Chemical Society 143 (9) (2021)
Koki Nakatsu, Masafumi Yanase, Gosuke Hayashi, Akimitsu Okamoto
Fmoc-Compatible and C-terminal-Sequence-Independent Peptide Alkyl Thioester Formation Using Cysteinylprolyl Imide. Organic letters 22 (12) (2020)
Ryuji Misawa, Tsuyoshi Minami, Akimitsu Okamoto, Yoshiho Ikeuchi
A Light-Inducible Hedgehog Signaling Activator Modulates Proliferation and Differentiation of Neural Cells. ACS chemical biology 15 (6) (2020)
Satoshi Yamaguchi, Risa Takagi, Tsuyoshi Hosogane, Yuki Ohashi, Yoko Sakai, Shouichi Sakakihara, Ryota Iino, Kazuhito V Tabata, Hiroyuki Noji, Akimitsu Okamoto
Single Cell Array Enclosed with a Photodegradable Hydrogel in Microwells for Image-Based Cell Classification and Selective Photorelease of Cells. ACS applied bio materials 3 (9) (2020)
Seiya Takemura, Hikaru Watanabe, Tatsuya Nishihara, Akimitsu Okamoto, Kazuhito Tanabe
Monitoring intracellular metal ion complexation with an acetylene-tagged ligand by Raman spectroscopy. RSC advances 10 (59) (2020)
Masafumi Yanase, Koki Nakatsu, Charlane Joy Cardos, Yoshiki Konda, Gosuke Hayashi, Akimitsu Okamoto
Cysteinylprolyl imide (CPI) peptide: a highly reactive and easily accessible crypto-thioester for chemical protein synthesis. Chemical science 10 (23) (2019)
Naoki Kamo, Gosuke Hayashi, Akimitsu Okamoto
Chemical Synthesis of Cys-Containing Protein via Chemoselective Deprotection with Different Palladium Complexes. Organic letters 21 (20) (2019)
Natalia Teresa Jarzębska, Satoshi Yamaguchi, Shin Izuta, Takahiro Kosaka, Shinya Yamahira, Teruyuki Nagamune, Akimitsu Okamoto
Photo-responsive materials with strong cell trapping ability for light-guided manipulation of nonadherent cells. Biomaterials science 7 (11) (2019)
Akimitsu Okamoto
Next-generation fluorescent nucleic acids probes for microscopic analysis of intracellular nucleic acids. Applied microscopy 49 (1) (2019)
Shin Izuta, Satoshi Yamaguchi, Takahiro Kosaka, Akimitsu Okamoto
Reversible and Photoresponsive Immobilization of Nonadherent Cells by Spiropyran-Conjugated PEG-Lipids. ACS applied bio materials 2 (1) (2019)
Gosuke Hayashi, Masafumi Yanase, Yu Nakatsuka, Akimitsu Okamoto
Simultaneous and Traceless Ligation of Peptide Fragments on DNA Scaffold. Biomacromolecules 20 (3) (2019)
Kunihiko Morihiro, Akimitsu Okamoto
A highly constrained nucleic acid analog based on α-l-threosamine. Nucleosides, nucleotides & nucleic acids 39 (1-3) (2019)
Jiazhuo Chen, Kunihiko Morihiro, Daisuke Fukui, Lihao Guo, Akimitsu Okamoto
Live-Cell Sensing of Telomerase Activity by Using Hybridization-Sensitive Fluorescent Oligonucleotide Probes. Chembiochem : a European journal of chemical biology 21 (7) (2019)
Naoki Kamo, Gosuke Hayashi, Akimitsu Okamoto
Triple Function of 4-Mercaptophenylacetic Acid Promotes One-Pot Multiple Peptide Ligation. Angewandte Chemie (International ed. in English) 57 (50) (2018)
Turja Kanti Debnath, Akimitsu Okamoto
Osmium Tag for Post-transcriptionally Modified RNA. Chembiochem : a European journal of chemical biology 19 (15) (2018)
Shin Izuta, Satoshi Yamaguchi, Ryuji Misawa, Shinya Yamahira, Modong Tan, Masahiro Kawahara, Tomoko Suzuki, Tomoko Takagi, Kae Sato, Motonao Nakamura, Teruyuki Nagamune, Akimitsu Okamoto
Microfluidic preparation of anchored cell membrane sheets for in vitro analyses and manipulation of the cytoplasmic face. Scientific reports 7 (1) (2017)
Takuma Sueoka, Gosuke Hayashi, Akimitsu Okamoto
Regulation of the Stability of the Histone H2A-H2B Dimer by H2A Tyr57 Phosphorylation. Biochemistry 56 (36) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Akimitsu Okamoto