Denis L J Lafontaine (Denis Lj Lafontaine)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 33

Top Venues

EMBO reports

Life science alliance

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Fonds National de la Recherche Scientifique (F.R.S./FNRS)

University of Namur (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Fonds National de la Recherche Scientifique (F.R.S./FNRS)

Belgium

Research Director :: RNA Molecular Biology

The Center For Microcopy and Molecular Imaging (CMMI)

Belgium

Founding Member and Co-director :: Automation & Quantitative Morphometry Division

Université Libre de Bruxelles

Belgium

Professor :: RNA Molecular Biology

Université Libre de Bruxelles

Belgium

Principal Investigator :: The Institute of Molecular Biology and Medecine

Fonds National de la Recherche Scientifique Scientifique (F.R.S./FNRS)

Belgium

Senior Research Associate :: RNA Molecular Biology

Fonds National de la Recherche Scientifique (F.R.S./FNRS)

Belgium

Research Associate :: RNA Molecular Biology

Wellcome Trust Centre for Cell Biology

United Kingdom

Research Associate :: In the laboratory of Pr David Tollervey

Wellcome Trust Centre for Cell Biology

United Kingdom

Post-doctoral Work :: In the laboratory of Pr David Tollervey

European Molecular Biology Laboratory

Germany

Post-doctoral Work :: Gene Expression Programme. In the laboratory of Pr David Tollervey

Education History

University of Namur

Belgium

PHD :: Department of Genetics. In the laboratory of Prof Jean Vandenhaute.

University of Namur

Belgium

MSC :: Department of Genetics. In the laboratory of Prof Jean Vandenhaute

Publications

Christiane Zorbas, Aynur Soenmez, Jean Léger, Christophe De Vleeschouwer, Denis L J Lafontaine
Detecting material state changes in the nucleolus by label-free digital holographic microscopy. EMBO reports (2024)
Amani Issa, Florence Schlotter, Justine Flayac, Jing Chen, Ludivine Wacheul, Manon Philippe, Lucas Sardini, Lalia Mostefa, Franck Vandermoere, Edouard Bertrand, Céline Verheggen, Denis L J Lafontaine, Séverine Massenet
The nucleolar phase of signal recognition particle assembly. Life science alliance 7 (8) (2024)
Christiane Zorbas, Aynur Soenmez, Jean Léger, Christophe De Vleeschouwer, Denis L J Lafontaine
Detecting material state changes in the nucleolus by label-free digital holographic microscopy. EMBO reports 25 (6) (2024)
Amani Issa, Florence Schlotter, Justine Flayac, Jing Chen, Ludivine Wacheul, Manon Philippe, Lucas Sardini, Lalia Mostefa, Franck Vandermoere, Edouard Bertrand, Céline Verheggen, Denis L J Lafontaine, Séverine Massenet
The nucleolar phase of signal recognition particle assembly. Life science alliance 7 (8) (2024)
Christiane Zorbas, Aynur Soenmez, Jean Léger, Christophe De Vleeschouwer, Denis L J Lafontaine
Detecting material state changes in the nucleolus by label-free digital holographic microscopy. EMBO reports 25 (6) (2024)
Amani Issa, Florence Schlotter, Justine Flayac, Jing Chen, Ludivine Wacheul, Manon Philippe, Lucas Sardini, Lalia Mostefa, Franck Vandermoere, Edouard Bertrand, Céline Verheggen, Denis L J Lafontaine, Séverine Massenet
The nucleolar phase of signal recognition particle assembly. Life science alliance 7 (8) (2024)
Christiane Zorbas, Aynur Soenmez, Jean Léger, Christophe De Vleeschouwer, Denis L J Lafontaine
Detecting material state changes in the nucleolus by label-free digital holographic microscopy. EMBO reports 25 (6) (2024)
Rebecca J Leeman-Neill, Dong Song, Jonathan Bizarro, Ludivine Wacheul, Gerson Rothschild, Sameer Singh, Yang Yang, Aditya Y Sarode, Kishore Gollapalli, Lijing Wu, Wanwei Zhang, Yiyun Chen, Max C Lauring, D Eric Whisenant, Shweta Bhavsar, Junghyun Lim, Steven Howard Swerdlow, Govind Bhagat, Qian Zhao, Luke E Berchowitz, Denis L J Lafontaine, Ji-Guang Wang, Uttiya Basu
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression. Nature genetics (2023)
Denis L J Lafontaine
In phase with the nucleolus. Cell research (2023)
Benjamin Cappe, Mike Vadi, Eliza Sack, Ludivine Wacheul, Bruno Verstraeten, Sara Dufour, Julien Franck, Wei Xie, Francis Impens, An Hendrix, Denis L J Lafontaine, Peter Vandenabeele, Franck B Riquet
Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis. Journal of extracellular vesicles 12 (10) (2023)
Marie-Line Bortolin-Cavaillé, Aurélie Quillien, Supuni Thalalla Gamage, Justin M Thomas, Aldema Sas-Chen, Sunny Sharma, Célia Plisson-Chastang, Laurence Vandel, Patrick Blader, Denis L J Lafontaine, Schraga Schwartz, Jordan L Meier, Jérôme Cavaille
Probing small ribosomal subunit RNA helix 45 acetylation across eukaryotic evolution. Nucleic acids research 50 (11) (2022)
Veronique Mathieu, Breana Laguera, Marco Masi, Sara Adriana Dulanto, Tanner W Bingham, Lucas W Hernandez, David Sarlah, Antonio Evidente, Denis L J Lafontaine, Alexander Kornienko, Michelle A Lane
Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells. Biomolecules 12 (9) (2022)
Marie-Françoise O'Donohue, Lydie M Da Costa, Marco Lezzerini, Sule Unal, Clément Joret, Marije Bartels, Eva Brilstra, Marijn Scheijde-Vermeulen, Ludivine Wacheul, Kim De Keersmaecker, Stijn Vereecke, Veerle Labarque, Manon Saby, Sophie D Lefevre, Jessica Platon, Nathalie Montel-Lehry, Nathalie Laugero, Eric Lacazette, Koen van Gassen, Riekelt H L Houtkooper, Pelin Ozlem Simsek-Kiper, Thierry Leblanc, Nese Yarali, Ömer Arda Çetinkaya, Nurten A Akarsu, Pierre-Emmanuel Gleizes, Denis L J Lafontaine, Alyson W MacInnes
HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia. Blood 139 (21) (2022)
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G Proud, Denis L J Lafontaine, Tsuyoshi Osawa
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors. Nature communications 13 (1) (2022)
Jonathan Delhermite, Lionel Tafforeau, Sunny Sharma, Virginie Marchand, Ludivine Wacheul, Ruben Lattuca, Simon Desiderio, Motorin Yuri, Eric Bellefroid, Denis L J Lafontaine
Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis. PLoS genetics 18 (1) (2022)
Isaac Planas-Sitjà, Jean-Louis Deneubourg, Denis L J Lafontaine, Ludivine Wacheul, Adam L Cronin
Differential Gene Expression Correlates with Behavioural Polymorphism during Collective Behaviour in Cockroaches. Animals : an open access journal from MDPI 12 (18) (2022)
Jonathan Bizarro, Svetlana Deryusheva, Ludivine Wacheul, Varun Gupta, Felix G M Ernst, Denis L J Lafontaine, Joseph G Gall, U Thomas Meier
Nopp140-chaperoned 2'-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity. Genes & development 35 (15-16) (2021)
Daniela Barros-Silva, Jonathan Klavert, Guido W Jenster, Carmen Jerónimo, Denis L J Lafontaine, Elena S Martens-Uzunova
The role of OncoSnoRNAs and Ribosomal RNA 2'-O-methylation in Cancer. RNA biology (2021)
Nicolas Thelen, Jean Defourny, Denis L J Lafontaine, Marc Thiry
Visualization of Chromatin in the Yeast Nucleus and Nucleolus Using Hyperosmotic Shock. International journal of molecular sciences 22 (3) (2021)
Amandine Duchemin, Tina M O'Grady, Sarah Hanache, Agnès Mereau, Marc Thiry, Ludivine Wacheul, Catherine Michaux, Eric Perpète, Eric Hervouet, Paul Peixoto, Felix G M Ernst, Yann Audic, Franck Dequiedt, Denis L J Lafontaine, Denis Mottet
DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity. Nature communications 12 (1) (2021)
Aynur Sönmez, Rasem Mustafa, Salome T Ryll, Francesca Tuorto, Ludivine Wacheul, Donatella Ponti, Christian Litke, Tanja Hering, Kerstin Kojer, Jenniver Koch, Claudia Pitzer, Joachim Kirsch, Andreas Neueder, Grzegorz Kreiner, Denis L J Lafontaine, Michael Orth, Birgit Liss, Rosanna Parlato
Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression. Cell death & disease 12 (12) (2021)
Jonathan Bizarro, Svetlana Deryusheva, Ludivine Wacheul, Varun Gupta, Felix G M Ernst, Denis L J Lafontaine, Joseph G Gall, U Thomas Meier
Nopp140-chaperoned 2'-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity. bioRxiv : the preprint server for biology (2021)
Yue Qin, Edward L Huttlin, Casper F Winsnes, Maya L Gosztyla, Ludivine Wacheul, Marcus R Kelly, Steven M Blue, Fan Zheng, Michael Chen, Leah V Schaffer, Katherine Licon, Anna Bäckström, Laura Pontano Vaites, John J Lee, Wei Ouyang, Sophie N Liu, Tian Zhang, Erica Silva, Jisoo Park, Adriana Pitea, Jason F Kreisberg, Steven P Gygi, Jianzhu Ma, J Wade Harper, Gene W Yeo, Denis L J Lafontaine, Emma Lundberg, Trey Ideker
A multi-scale map of cell structure fusing protein images and interactions. Nature (2021)
Denis L J Lafontaine, Joshua A Riback, Rümeyza Bascetin, Clifford P Brangwynne
The nucleolus as a multiphase liquid condensate. Nature reviews. Molecular cell biology 22 (3) (2020)
Clemens Heissenberger, Jarod A Rollins, Teresa L Krammer, Fabian Nagelreiter, Isabella Stocker, Ludivine Wacheul, Anton Shpylovyi, Koray Tav, Santina Snow, Johannes Grillari, Aric N Rogers, Denis L J Lafontaine, Markus Schosserer
The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans. eLife 9 (2020)
Jessica Leismann, Mariangela Spagnuolo, Mihika Pradhan, Ludivine Wacheul, Minh Anh Vu, Michael Musheev, Pablo Mier, Miguel A Andrade-Navarro, Marc Graille, Christof Niehrs, Denis L J Lafontaine, Jean-Yves Roignant
The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. EMBO reports 21 (7) (2020)
Lian Zhu, Tiffany M Richardson, Ludivine Wacheul, Ming-Tzo Wei, Marina Feric, Gena Whitney, Denis L J Lafontaine, Clifford P Brangwynne
Controlling the material properties and rRNA processing function of the nucleolus using light. Proceedings of the National Academy of Sciences of the United States of America 116 (35) (2019)
Vassiliki Stamatopoulou, Pascaline Parisot, Christophe De Vleeschouwer, Denis L J Lafontaine
Use of the iNo score to discriminate normal from altered nucleolar morphology, with applications in basic cell biology and potential in human disease diagnostics. Nature protocols 13 (10) (2019)
Roberto Vendramin, Yvessa Verheyden, Hideaki Ishikawa, Lucas Goedert, Emilien Nicolas, Kritika Saraf, Alexandros Armaos, Riccardo Delli Ponti, Keichi Izumikawa, Pieter Mestdagh, Denis L J Lafontaine, Gian Gaetano Tartaglia, Nobuhiro Takahashi, Jean-Christophe Marine, Eleonora Leucci
SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation. Nature structural & molecular biology 25 (11) (2018)
Virginie Marchand, Lilia Ayadi, Felix G M Ernst, Jasmin Hertler, Valérie Bourguignon-Igel, Adeline Galvanin, Annika Kotter, Mark Helm, Denis L J Lafontaine, Motorin Yuri
AlkAniline-Seq: Profiling of m7 G and m3 C RNA Modifications at Single Nucleotide Resolution. Angewandte Chemie (International ed. in English) 57 (51) (2018)
Sunny Sharma, Johannes David Hartmann, Peter Watzinger, Arvid Klepper, Christian Peifer, Peter Kötter, Denis L J Lafontaine, Karl-Dieter Entian
A single N1-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes. Scientific reports 8 (1) (2018)
Sunny Sharma, Virginie Marchand, Yuri Motorin, Denis L J Lafontaine
Identification of sites of 2'-O-methylation vulnerability in human ribosomal RNAs by systematic mapping. Scientific reports 7 (1) (2017)
Daniel Z Bar, Chayki Charar, Jehudith Dorfman, Tam Yadid, Lionel Tafforeau, Denis L J Lafontaine, Yosef Gruenbaum
Cell size and fat content of dietary-restricted Caenorhabditis elegans are regulated by ATX-2, an mTOR repressor. Proceedings of the National Academy of Sciences of the United States of America 113 (32) (2016)

Denis L J Lafontaine.css-eqlu8i{font-size:small;padding-left:4px;} (Denis Lj Lafontaine)

Publication Activity (10 Years)

Top Topics

Top Venues

Denis L J Lafontaine (Denis Lj Lafontaine)