Hiroyuki Aburatani (H Aburatani)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 50

Top Topics

Left Ventricular

Dna Methylation

Top Venues

Nature communications

Nature genetics

Scientific reports

Cancer immunology research

This page only lists publications with an associated author ORCID identifier.

Publications

Manami Katoh, Seitaro Nomura, Shintaro Yamada, Masamichi Ito, Hiroki Hayashi, Mikako Katagiri, Tuolisi Heryed, Takayuki Fujiwara, Norifumi Takeda, Miyuki Nishida, Maki Sugaya, Miki Kato, Tsuyoshi Osawa, Hiroyuki Abe, Yoshitaka Sakurai, Toshiyuki Ko, Kanna Fujita, Bo Zhang, Satoshi Hatsuse, Takanobu Yamada, Shunsuke Inoue, Zhehao Dai, Masayuki Kubota, Kousuke Sawami, Minoru Ono, Hiroyuki Morita, Yoshiaki Kubota, Seiya Mizuno, Satoru Takahashi, Makoto Nakanishi, Tetsuo Ushiku, Hironori Nakagami, Hiroyuki Aburatani, Issei Komuro
Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7. Circulation (2024)
Masamichi Ito, Manami Katoh, Tatsuro Sassa, Toshiyuki Ko, Kanna Fujita, Shintaro Yamada, Koichiro Miura, Masashi Toyoda, Shuji Takada, Takashige Tobita, Mikako Katagiri, Masayuki Kubota, Takanobu Yamada, Satoshi Hatsuse, Hiroyuki Morita, Masashi Ikeuchi, Katsuhisa Matsuura, Akihiro Umezawa, Seitaro Nomura, Hiroyuki Aburatani, Issei Komuro
LMNA Q353R Mutation Causes Dilated Cardiomyopathy Through Impaired Vitamin D Signaling. Circulation 150 (12) (2024)
Hirofumi Mikami, Shu Feng, Yutaka Matsuda, Shinya Ishii, Sotaro Naoi, Yumiko Azuma, Hiroaki Nagano, Kentaro Asanuma, Yoko Kayukawa, Toshiaki Tsunenari, Shogo Kamikawaji, Ryutaro Iwabuchi, Junko Shinozuka, Masaki Yamazaki, Haruka Kuroi, Samantha Shu Wen Ho, Gan Siok Wan, Priyanka Chichili, Chai Ling Pang, Chiew Ying Yeo, Shun Shimizu, Naoka Hironiwa, Yasuko Kinoshita, Yuichiro Shimizu, Akihisa Sakamoto, Masaru Muraoka, Noriyuki Takahashi, Tatsuya Kawa, Hirotake Shiraiwa, Futa Mimoto, Kenji Kashima, Mika Kamata-Sakurai, Shumpei Ishikawa, Hiroyuki Aburatani, Takehisa Kitazawa, Tomoyuki Igawa
Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer. Cancer immunology research 12 (6) (2024)
Manami Katoh, Seitaro Nomura, Shintaro Yamada, Masamichi Ito, Hiroki Hayashi, Mikako Katagiri, Tuolisi Heryed, Takayuki Fujiwara, Norifumi Takeda, Miyuki Nishida, Maki Sugaya, Miki Kato, Tsuyoshi Osawa, Hiroyuki Abe, Yoshitaka Sakurai, Toshiyuki Ko, Kanna Fujita, Bo Zhang, Satoshi Hatsuse, Takanobu Yamada, Shunsuke Inoue, Zhehao Dai, Masayuki Kubota, Kousuke Sawami, Minoru Ono, Hiroyuki Morita, Yoshiaki Kubota, Seiya Mizuno, Satoru Takahashi, Makoto Nakanishi, Tetsuo Ushiku, Hironori Nakagami, Hiroyuki Aburatani, Issei Komuro
Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7. Circulation 150 (5) (2024)
Hirofumi Mikami, Shu Feng, Yutaka Matsuda, Shinya Ishii, Sotaro Naoi, Yumiko Azuma, Hiroaki Nagano, Kentaro Asanuma, Yoko Kayukawa, Toshiaki Tsunenari, Shogo Kamikawaji, Ryutaro Iwabuchi, Junko Shinozuka, Masaki Yamazaki, Haruka Kuroi, Samantha Shu Wen Ho, Gan Siok Wan, Priyanka Chichili, Chai Ling Pang, Chiew Ying Yeo, Shun Shimizu, Naoka Hironiwa, Yasuko Kinoshita, Yuichiro Shimizu, Akihisa Sakamoto, Masaru Muraoka, Noriyuki Takahashi, Tatsuya Kawa, Hirotake Shiraiwa, Futa Mimoto, Kenji Kashima, Mika Kamata-Sakurai, Shumpei Ishikawa, Hiroyuki Aburatani, Takehisa Kitazawa, Tomoyuki Igawa
Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer. Cancer immunology research (2024)
Hirofumi Mikami, Shu Feng, Yutaka Matsuda, Shinya Ishii, Sotaro Naoi, Yumiko Azuma, Hiroaki Nagano, Kentaro Asanuma, Yoko Kayukawa, Toshiaki Tsunenari, Shogo Kamikawaji, Ryutaro Iwabuchi, Junko Shinozuka, Masaki Yamazaki, Haruka Kuroi, Samantha Shu Wen Ho, Gan Siok Wan, Priyanka Chichili, Chai Ling Pang, Chiew Ying Yeo, Shun Shimizu, Naoka Hironiwa, Yasuko Kinoshita, Yuichiro Shimizu, Akihisa Sakamoto, Masaru Muraoka, Noriyuki Takahashi, Tatsuya Kawa, Hirotake Shiraiwa, Futa Mimoto, Kenji Kashima, Mika Kamata-Sakurai, Shumpei Ishikawa, Hiroyuki Aburatani, Takehisa Kitazawa, Tomoyuki Igawa
Engineering CD3/CD137 dual specificity into a DLL3-targeted T-cell engager enhances T-cell infiltration and efficacy against small cell lung cancer. Cancer immunology research (2024)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics 55 (2) (2023)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics (2023)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics 55 (2) (2023)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics 55 (2) (2023)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics 55 (2) (2023)
Shintaro Yamada, Toshiyuki Ko, Masamichi Ito, Tatsuro Sassa, Seitaro Nomura, Hiromichi Okuma, Mayuko Sato, Tsuyoshi Imasaki, Satoshi Kikkawa, Bo Zhang, Takanobu Yamada, Yuka Seki, Kanna Fujita, Manami Katoh, Masayuki Kubota, Satoshi Hatsuse, Mikako Katagiri, Hiromu Hayashi, Momoko Hamano, Norifumi Takeda, Hiroyuki Morita, Shuji Takada, Masashi Toyoda, Masanobu Uchiyama, Masashi Ikeuchi, Kiminori Toyooka, Akihiro Umezawa, Yoshihiro Yamanishi, Ryo Nitta, Hiroyuki Aburatani, Issei Komuro
TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy. Science advances 9 (15) (2023)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics 55 (2) (2023)
Kazuo Miyazawa, Shefali S Verma, Masamichi Ito, Zhaonan Zou, Masayuki Kubota, Seitaro Nomura, Hiroshi Matsunaga, Satoshi Koyama, Hirotaka Ieki, Masato Akiyama, Yoshinao Koike, Ryo Kurosawa, Hiroki Yoshida, Kouichi Ozaki, Yoshihiro Onouchi, null null, Atsushi Takahashi, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Yukihide Momozawa, Chikashi C Terao, Shinya Oki, Hiroshi Akazawa, Yoichiro Kamatani, Issei Komuro
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction. Nature genetics 55 (2) (2023)
Kotaro Soeda, Takayoshi Sasako, Kenichiro Enooku, Naoto Kubota, Naoki Kobayashi, Yoshiko Matsumoto Ikushima, Motoharu Awazawa, Ryotaro Bouchi, Gotaro Toda, Tomoharu Yamada, Takuma Nakatsuka, Ryosuke Tateishi, Miwako Kakiuchi, Shogo Yamamoto, Kenji Tatsuno, Koji Atarashi, Wataru Suda, Kenya Honda, Hiroyuki Aburatani, Toshimasa Yamauchi, Mitsuhiro Fujishiro, Tetsuo Noda, Kazuhiko Koike, Takashi Kadowaki, Kohjiro Ueki
Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis. Nature communications 14 (1) (2023)
Yasushi Totoki, Mihoko Saito-Adachi, Yuichi Shiraishi, Daisuke Komura, Hiromi Nakamura, Akihiro Suzuki, Kenji Tatsuno, Hirofumi Rokutan, Natsuko Hama, Shogo Yamamoto, Hanako Ono, Yasuhito Arai, Fumie Hosoda, Hiroto Katoh, Kenichi Chiba, Naoko Iida, Genta Nagae, Hiroki Ueda, Chen Shihang, Shigeki Sekine, Hiroyuki Abe, Sachiyo Nomura, Tetsuya Matsuura, Eiji Sakai, Takashi Ohshima, Yasushi Rino, Khay Guan Yeoh, Jimmy Bok-Yan So, Kaushal Sanghvi, Richie Soong, Akihiko Fukagawa, Hirotsugu Shiroma, Mamoru Kato, Yasuyuki Seto, Tetsuo Ushiku, Hirokazu Takahashi, Hitoshi Katai, Patrick Tan, Shumpei Ishikawa, Hiroyuki Aburatani, Tatsuhiro Shibata
Multiancestry genomic and transcriptomic analysis of gastric cancer. Nature genetics (2023)
Kenta Koyama, Gosuke Hayashi, Hiroki Ueda, Satoshi Ota, Genta Nagae, Hiroyuki Aburatani, Akimitsu Okamoto
Base-resolution analysis of 5-hydroxymethylcytidine by selective oxidation and reverse transcription arrest. Organic & biomolecular chemistry 19 (29) (2022)
Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Motohiro Kato, Akira Oka, Katsuyoshi Koh, Yusuke Sato, Hiroko Tanaka, Satoru Miyano, Tomoko Kawai, Kenichiro Hata, Hiroo Ueno, Yasuhito Nannya, Hiromichi Suzuki, Kenichi Yoshida, Yoichi Fujii, Genta Nagae, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita
Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism. Oncogene 41 (46) (2022)
Hiroki Takahashi, Ge Yang, Takeshi Yoneshiro, Yohei Abe, Ryo Ito, Chaoran Yang, Junna Nakazono, Mayumi Okamoto-Katsuyama, Aoi Uchida, Makoto Arai, Hitomi Jin, Hyunmi Choi, Myagmar Tumenjargal, Shiyu Xie, Ji Zhang, Hina Sagae, Yanan Zhao, Rei Yamaguchi, Yu Nomura, Yuichi Shimizu, Kaito Yamada, Satoshi Yasuda, Hitoshi Kurumizaka, Toshiya Tanaka, Youichiro Wada, Tatsuhiko Kodama, Hiroyuki Aburatani, Min-Sheng Zhu, Takeshi Inagaki, Timothy F Osborne, Takeshi Kawamura, Yasushi Ishihama, Yoshihiro Matsumura, Juro Sakai
MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis. Nature communications 13 (1) (2022)
Shintaro Yamada, Toshiyuki Ko, Satoshi Hatsuse, Seitaro Nomura, Bo Zhang, Zhehao Dai, Shunsuke Inoue, Masayuki Kubota, Kosuke Sawami, Takanobu Yamada, Tatsuro Sassa, Mikako Katagiri, Kanna Fujita, Manami Katoh, Masamichi Ito, Mutsuo Harada, Haruhiro Toko, Norifumi Takeda, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro
Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction. Nature cardiovascular research 1 (11) (2022)
Ryoya Nakagawa, Soh Ishiguro, Sae Okazaki, Hideto Mori, Mamoru Tanaka, Hiroyuki Aburatani, Nozomu Yachie, Hiroshi Nishimasu, Osamu Nureki
Engineered Campylobacter jejuni Cas9 variant with enhanced activity and broader targeting range. Communications biology 5 (1) (2022)
Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Chika Yamagishi, Moe Tamura, Yosuke Tanaka, Shuhei Asada, Reina Takeda, Akiho Tsuchiya, Xiaonan Wang, Kenichi Yoshida, Yasuhito Nannya, Hiroo Ueno, Ryo Akazawa, Itaru Kato, Takashi Mikami, Kentaro Watanabe, Masahiro Sekiguchi, Masafumi Seki, Shunsuke Kimura, Mitsuteru Hiwatari, Motohiro Kato, Shiro Fukuda, Kenji Tatsuno, Shuichi Tsutsumi, Akinori Kanai, Toshiya Inaba, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Rishi Sury Kotecha, Mark N Cruickshank, Fumihiko Ishikawa, Tomohiro Morio, Minenori Eguchi-Ishimae, Takao Deguchi, Nobutaka Kiyokawa, Yuki Arakawa, Katsuyoshi Koh, Yuki Aoki, Takashi Ishihara, Masanori Yoshida, Takako Miyamura, Eiichi Ishii, Shuki Mizutani, Nicola K Wilson, Berthold Göttgens, Satoru Miyano, Toshio Kitamura, Susumu Goyama, Akihiko Yokoyama, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia. Nature communications 13 (1) (2022)
Toshiyuki Ko, Seitaro Nomura, Shintaro Yamada, Kanna Fujita, Takanori Fujita, Masahiro Satoh, Chio Oka, Manami Katoh, Masamichi Ito, Mikako Katagiri, Tatsuro Sassa, Bo Zhang, Satoshi Hatsuse, Takanobu Yamada, Mutsuo Harada, Haruhiro Toko, Eisuke Amiya, Masaru Hatano, Osamu Kinoshita, Kan Nawata, Hiroyuki Abe, Tetsuo Ushiku, Minoru Ono, Masashi Ikeuchi, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro
Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis. Nature communications 13 (1) (2022)
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G Proud, Denis L J Lafontaine, Tsuyoshi Osawa
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors. Nature communications 13 (1) (2022)
Shintaro Yamada, Toshiyuki Ko, Satoshi Hatsuse, Seitaro Nomura, Bo Zhang, Zhehao Dai, Shunsuke Inoue, Masayuki Kubota, Kosuke Sawami, Takanobu Yamada, Tatsuro Sassa, Mikako Katagiri, Kanna Fujita, Manami Katoh, Masamichi Ito, Mutsuo Harada, Haruhiro Toko, Norifumi Takeda, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro
Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction. Nature cardiovascular research 1 (11) (2022)
Shintaro Yamada, Toshiyuki Ko, Satoshi Hatsuse, Seitaro Nomura, Bo Zhang, Zhehao Dai, Shunsuke Inoue, Masayuki Kubota, Kosuke Sawami, Takanobu Yamada, Tatsuro Sassa, Mikako Katagiri, Kanna Fujita, Manami Katoh, Masamichi Ito, Mutsuo Harada, Haruhiro Toko, Norifumi Takeda, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro
Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction. Nature cardiovascular research 1 (11) (2022)
Genta Nagae, Shogo Yamamoto, Masashi Fujita, Takanori Fujita, Aya Nonaka, Takayoshi Umeda, Shiro Fukuda, Kenji Tatsuno, Kazuhiro Maejima, Akimasa Hayashi, Sho Kurihara, Masato Kojima, Tomoro Hishiki, Kenichiro Watanabe, Kohmei Ida, Michihiro Yano, Yoko Hiyama, Yukichi Tanaka, Takeshi Inoue, Hiroki Ueda, Hidewaki Nakagawa, Hiroyuki Aburatani, Eiso Hiyama
Genetic and epigenetic basis of hepatoblastoma diversity. Nature communications 12 (1) (2021)
Yoshihiro Matsumura, Ryo Ito, Ayumu Yajima, Rei Yamaguchi, Toshiya Tanaka, Takeshi Kawamura, Kenta Magoori, Yohei Abe, Aoi Uchida, Takeshi Yoneshiro, Hiroyuki Hirakawa, Ji Zhang, Makoto Arai, Chaoran Yang, Ge Yang, Hiroki Takahashi, Hitomi Fujihashi, Ryo Nakaki, Shogo Yamamoto, Satoshi Ota, Shuichi Tsutsumi, Shin-Ichi Inoue, Hitoshi Kurumizaka, Youichiro Wada, Tatsuhiko Kodama, Takeshi Inagaki, Timothy F Osborne, Hiroyuki Aburatani, Koichi Node, Juro Sakai
Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis. Nature communications 12 (1) (2021)
Satoshi Koyama, Shefali S Verma, Chikashi C Terao, Masato Akiyama, Momoko Horikoshi, Yukihide Momozawa, Hiroshi Matsunaga, Hirotaka Ieki, Kouichi Ozaki, Yoshihiro Onouchi, Atsushi Takahashi, Seitaro Nomura, Hiroyuki Morita, Hiroshi Akazawa, Changhoon Kim, Jeong-Sun Seo, Koichiro Higasa, Motoki Iwasaki, Taiki Yamaji, Norie Sawada, Shoichiro Tsugane, Teruhide Koyama, Hiroaki Ikezaki, Naoyuki Takashima, Keitaro Tanaka, Kokichi Arisawa, Kiyonori Kuriki, Mariko Naito, Kenji Wakai, Shinichiro Suna, Yasuhiko Sakata, Hiroshi Sato, Masatsugu Hori, Yasushi Sakata, Koichi Matsuda, Yoshinori Murakami, Hiroyuki Aburatani, Michiaki Kubo, Fumihiko Matsuda, Yoichiro Kamatani, Issei Komuro
Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. Nature genetics 52 (11) (2020)
Atsuya Nishiyama, Christopher B Mulholland, Sebastian Bultmann, Satomi Kori, Akinori Endo, Yasushi Saeki, Weihua Qin, Carina Trummer, Yoshie Chiba, Haruka Yokoyama, Soichiro Kumamoto, Toru Kawakami, Hironobu Hojo, Genta Nagae, Hiroyuki Aburatani, Keiji Tanaka, Kyohei Arita, Heinrich Leonhardt, Makoto Nakanishi
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nature communications 11 (1) (2020)
Rina C Sakata, Soh Ishiguro, Hideto Mori, Mamoru Tanaka, Kenji Tatsuno, Hiroki Ueda, Shogo Yamamoto, Motoaki Seki, Nanami Masuyama, Keiji Nishida, Hiroshi Nishimasu, Kazuharu Arakawa, Akihiko Kondo, Osamu Nureki, Masaru Tomita, Hiroyuki Aburatani, Nozomu Yachie
Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Nature biotechnology 38 (7) (2020)
Yuta Hiraike, Hironori Waki, Kana Miyake, Takahito Wada, Misato Oguchi, Kaede Saito, Shuichi Tsutsumi, Hiroyuki Aburatani, Toshimasa Yamauchi, Takashi Kadowaki
NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation. PLoS genetics 16 (9) (2020)
Akihiro Suzuki, Hiroto Katoh, Daisuke Komura, Miwako Kakiuchi, Amane Tagashira, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Genta Nagae, Shiro Fukuda, Takayoshi Umeda, Yasushi Totoki, Hiroyuki Abe, Tetsuo Ushiku, Tetsuya Matsuura, Eiji Sakai, Takashi Ohshima, Sachiyo Nomura, Yasuyuki Seto, Tatsuhiro Shibata, Yasushi Rino, Atsushi Nakajima, Masashi Fukayama, Shumpei Ishikawa, Hiroyuki Aburatani
Defined lifestyle and germline factors predispose Asian populations to gastric cancer. Science advances 6 (19) (2020)
Masato Morikawa, Yoshihide Mitani, Katarina Holmborn, Taichi Kato, Daizo Koinuma, Junko Maruyama, Eleftheria Vasilaki, Hirofumi Sawada, Mai Kobayashi, Takayuki Ozawa, Yasuyuki Morishita, Yasumasa Bessho, Shingo Maeda, Johan Ledin, Hiroyuki Aburatani, Ryoichiro Kageyama, Kazuo Maruyama, Carl-Henrik Heldin, Kohei Miyazono
The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. Science signaling 12 (607) (2019)
Masashi Nomura, Kuniaki Saito, Koki Aihara, Genta Nagae, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Shiro Fukuda, Takayoshi Umeda, Shota Tanaka, Shunsaku Takayanagi, Ryohei Otani, Takahide Nejo, Taijun Hana, Satoshi Takahashi, Yosuke Kitagawa, Mayu Omata, Fumi Higuchi, Taishi Nakamura, Yoshihiro Muragaki, Yoshitaka Narita, Motoo Nagane, Ryo Nishikawa, Keisuke Ueki, Nobuhito Saito, Hiroyuki Aburatani, Akitake Mukasa
Publisher Correction: DNA demethylation is associated with malignant progression of lower-grade gliomas. Scientific reports 9 (1) (2019)
Masashi Nomura, Kuniaki Saito, Koki Aihara, Genta Nagae, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Shiro Fukuda, Takayoshi Umeda, Shota Tanaka, Shunsaku Takayanagi, Ryohei Otani, Takahide Nejo, Taijun Hana, Satoshi Takahashi, Yosuke Kitagawa, Mayu Omata, Fumi Higuchi, Taishi Nakamura, Yoshihiro Muragaki, Yoshitaka Narita, Motoo Nagane, Ryo Nishikawa, Keisuke Ueki, Nobuhito Saito, Hiroyuki Aburatani, Akitake Mukasa
DNA demethylation is associated with malignant progression of lower-grade gliomas. Scientific reports 9 (1) (2019)
Mohammad Masoudi, Motoaki Seki, Razieh Yazdanparast, Nozomu Yachie, Hiroyuki Aburatani
A genome-scale CRISPR/Cas9 knockout screening reveals SH3D21 as a sensitizer for gemcitabine. Scientific reports 9 (1) (2019)
Imari Mimura, Yosuke Hirakawa, Yasuharu Kanki, Ryo Nakaki, Yutaka Suzuki, Tetsuhiro Tanaka, Hiroyuki Aburatani, Masaomi Nangaku
Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes. Scientific reports 8 (1) (2018)
Nao Nagai, Hiroto Ohguchi, Ryo Nakaki, Yoshihiro Matsumura, Yasuharu Kanki, Juro Sakai, Hiroyuki Aburatani, Takashi Minami
Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition. PLoS genetics 14 (11) (2018)
Tomoko Saito, Atsushi Niida, Ryutaro Uchi, Hidenari Hirata, Hisateru Komatsu, Shotaro Sakimura, Shuto Hayashi, Sho Nambara, Yosuke Kuroda, Shuhei Ito, Hidetoshi Eguchi, Takaaki Masuda, Keishi Sugimachi, Taro Tobo, Haruto Nishida, Tsutomu Daa, Kenichi Chiba, Yuichi Shiraishi, Tetsuichi Yoshizato, Masaaki Kodama, Tadayoshi Okimoto, Kazuhiro Mizukami, Ryo Ogawa, Kazuhisa Okamoto, Mitsutaka Shuto, Kensuke Fukuda, Yusuke Matsui, Teppei Shimamura, Takanori Hasegawa, Yuichiro Doki, Satoshi Nagayama, Kazutaka Yamada, Mamoru Kato, Tatsuhiro Shibata, Masaki Mori, Hiroyuki Aburatani, Kazunari Murakami, Yutaka Suzuki, Seishi Ogawa, Satoru Miyano, Koshi Mimori
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer. Nature communications 9 (1) (2018)
Natsuko Hama, Yasushi Totoki, Fumihito Miura, Kenji Tatsuno, Mihoko Saito-Adachi, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Tomoko Urushidate, Shoko Ohashi, Wakako Mukai, Nobuyoshi Hiraoka, Hiroyuki Aburatani, Takashi Ito, Tatsuhiro Shibata
Epigenetic landscape influences the liver cancer genome architecture. Nature communications 9 (1) (2018)
Yohei Abe, Yosuke Fujiwara, Hiroki Takahashi, Yoshihiro Matsumura, Tomonobu Sawada, Shuying Jiang, Ryo Nakaki, Aoi Uchida, Noriko Nagao, Makoto Naito, Shingo Kajimura, Hitoshi Kurumizaka, Timothy F Osborne, Hiroyuki Aburatani, Tatsuhiko Kodama, Takeshi Inagaki, Juro Sakai
Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch. Nature communications 9 (1) (2018)
Hiroshi Nishimasu, Xi Shi, Soh Ishiguro, Linyi Gao, Seiichi Hirano, Sae Okazaki, Taichi Noda, Omar O Abudayyeh, Jonathan Samuel Gootenberg, Hideto Mori, Seiya Oura, Benjamin Holmes, Mamoru Tanaka, Motoaki Seki, Hisato Hirano, Hiroyuki Aburatani, Ryuichiro Ishitani, Masahito Ikawa, Nozomu Yachie, Feng Zhang, Osamu Nureki
Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science (New York, N.Y.) 361 (6408) (2018)
Zhenghao Li, Hisanori Takenobu, Amallia Nuggetsiana Setyawati, Nobuhiro Akita, Masayuki Haruta, Shunpei Satoh, Yoshitaka Shinno, Koji Chikaraishi, Kyosuke Mukae, Jesmin Akter, Ryuichi P Sugino, Atsuko Nakazawa, Akira Nakagawara, Hiroyuki Aburatani, Miki Ohira, Takehiko Kamijo
EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications. Oncogene 37 (20) (2018)
Takashige Tobita, Seitaro Nomura, Takanori Fujita, Hiroyuki Morita, Yoshihiro Asano, Kenji Onoue, Masamichi Ito, Yasushi Imai, Atsushi Suzuki, Toshiyuki Ko, Masahiro Satoh, Kanna Fujita, Atsuhiko T Naito, Yoshiyuki Furutani, Haruhiro Toko, Mutsuo Harada, Eisuke Amiya, Masaru Hatano, Eiki Takimoto, Tsuyoshi Shiga, Toshio Nakanishi, Yasushi Sakata, Minoru Ono, Yoshihiko Saito, Seiji Takashima, Nobuhisa Hagiwara, Hiroyuki Aburatani, Issei Komuro
Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling. Scientific reports 8 (1) (2018)
Seitaro Nomura, Masahiro Satoh, Takanori Fujita, Tomoaki Higo, Tomokazu S Sumida, Toshiyuki Ko, Toshihiro Yamaguchi, Takashige Tobita, Atsuhiko T Naito, Masamichi Ito, Kanna Fujita, Mutsuo Harada, Haruhiro Toko, Yoshio Kobayashi, Kaoru Ito, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Hiroyuki Aburatani, Issei Komuro
Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure. Nature communications 9 (1) (2018)
K C Kawabata, Y Hayashi, D Inoue, H Meguro, H Sakurai, T Fukuyama, Y Tanaka, S Asada, T Fukushima, R Nagase, R Takeda, Y Harada, J Kitaura, S Goyama, H Harada, Hiroyuki Aburatani, T Kitamura
High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis. Leukemia 32 (2) (2017)
Junna Yamaguchi, Tetsuhiro Tanaka, Hisako Saito, Seitaro Nomura, Hiroyuki Aburatani, Hironori Waki, Takashi Kadowaki, Masaomi Nangaku
Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner. Scientific reports 7 (1) (2017)
Takashige Tobita, Seitaro Nomura, Hiroyuki Morita, Toshiyuki Ko, Takanori Fujita, Haruhiro Toko, Kenta Uto, Nobuhisa Hagiwara, Hiroyuki Aburatani, Issei Komuro
Identification of MYLK3 mutations in familial dilated cardiomyopathy. Scientific reports 7 (1) (2017)
Yuta Hiraike, Hironori Waki, Jing Yu, Masahiro Nakamura, Kana Miyake, Gaku Nagano, Ryo Nakaki, Ken Suzuki, Hirofumi Kobayashi, Shogo Yamamoto, Wei Sun, Tomohisa Aoyama, Yusuke Hirota, Haruya Ohno, Kenji Oki, Masayasu Yoneda, Andrew P White, Yu-Hua Tseng, Aaron M Cypess, Therese J Larsen, Naja Z Jespersen, Camilla Scheele, Shuichi Tsutsumi, Hiroyuki Aburatani, Toshimasa Yamauchi, Takashi Kadowaki
NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program. Nature cell biology 19 (9) (2017)