Akseli Niemelä

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 6

Top Topics

Low Density Lipoprotein

Molecular Dynamics Simulations

Top Venues

PLoS computational biology

Molecular pharmaceutics

Molecular pharmacology

This page only lists publications with an associated author ORCID identifier.

Publications

Akseli Niemelä, Artturi Koivuniemi
Systematic evaluation of lecithin:cholesterol acyltransferase binding sites in apolipoproteins via peptide based nanodiscs: regulatory role of charged residues at positions 4 and 7. PLoS computational biology 20 (5) (2024)
Kelly A Manthei, Grace E Tremonti, Louise Chang, Akseli Niemelä, Laura Giorgi, Artturi Koivuniemi, John Joseph Grubb Tesmer
Rescue of Familial Lecithin:Cholesterol Acyltranferase Deficiency Mutations with an Allosteric Activator . Molecular pharmacology (2024)
Akseli Niemelä, Artturi Koivuniemi
Systematic evaluation of lecithin:Cholesterol acyltransferase binding sites in apolipoproteins via peptide based nanodiscs: Regulatory role of charged residues at positions 4 and 7. PLoS computational biology 20 (5) (2024)
Akseli Niemelä, Artturi Koivuniemi
Systematic evaluation of lecithin:cholesterol acyltransferase binding sites in apolipoproteins via peptide based nanodiscs: regulatory role of charged residues at positions 4 and 7. PLoS computational biology 20 (5) (2024)
Laura Giorgi, Akseli Niemelä, Esa-Pekka Kumpula, Ossi Natri, Petteri Parkkila, Juha T Huiskonen, Artturi Koivuniemi
Mechanistic Insights into the Activation of Lecithin-Cholesterol Acyltransferase in Therapeutic Nanodiscs Composed of Apolipoprotein A-I Mimetic Peptides and Phospholipids. Molecular pharmaceutics 19 (11) (2022)
Akseli Niemelä, Artturi Koivuniemi
Positive allosteric modulators of lecithin: Cholesterol acyltransferase adjust the orientation of the membrane-binding domain and alter its spatial free energy profile. PLoS computational biology 17 (3) (2021)