Alena Zíková

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Venues

Journal of medicinal chemistry

PLoS pathogens

PLoS neglected tropical diseases

The Journal of biological chemistry

Biology Centre

University of South Bohemia in České Budějovice (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Biology Centre

Czechia

Group leader :: Institute of Parasitology

Seattle Biomed

United States

Postdoctoral scientist

Education History

University of South Bohemia in České Budějovice Sep 01 2002 - Sep 01 2006

Czechia

PHD

Publications

Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry 67 (9) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry 67 (9) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry 67 (9) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry (2024)
Matus Valach, Corinna Benz, Lisbeth-Carolina Aguilar, Ondřej Gahura, Drahomíra Faktorová, Alena Zíková, Marlene Oeffinger, Gertraud Burger, Michael W Gray, Julius Lukeš
Miniature RNAs are embedded in an exceptionally protein-rich mitoribosome via an elaborate assembly pathway. Nucleic acids research (2023)
Gergana Taleva, Michaela Husová, Brian Panicucci, Carolina Hierro-Yap, Erika Pineda, Marc Biran, Martin Moos, Petr Šimek, Falk Butter, Frédéric Bringaud, Alena Zíková
Mitochondrion of the Trypanosoma brucei long slender bloodstream form is capable of ATP production by substrate-level phosphorylation. PLoS pathogens 19 (10) (2023)
Tomáš Klejch, Dianne T Keough, Gordon King, Eva Doleželová, Michal Česnek, Miloš Buděšínský, Alena Zíková, Zlatko Janeba, Luke W Guddat, Dana Hocková
Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases. Journal of medicinal chemistry 65 (5) (2022)
Ondřej Gahura, Alexander Mühleip, Carolina Hierro-Yap, Brian Panicucci, Minal Jain, David Hollaus, Martina Slapničková, Alena Zíková, Alexey Amunts
An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases. Nature communications 13 (1) (2022)
Alena Zíková
Mitochondrial adaptations throughout the Trypanosoma brucei life cycle. The Journal of eukaryotic microbiology 69 (6) (2022)
Ondřej Štěpánek, Adéla Čmoková, Eliška Procházková, Valéria Grobárová, Jan Černý, Martina Slapničková, Alena Zíková, Miroslav Kolařík, Ondřej Baszczyňski
Piperazine-Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens. ChemMedChem 17 (21) (2022)
Oriana Villafraz, Marc Biran, Erika Pineda, Nicolas Plazolles, Edern Cahoreau, Rodolpho Ornitz Oliveira Souza, Magali Thonnus, Stefan Allmann, Emmanuel Tetaud, Loïc Rivière, Ariel Mariano Silber, Michael P Barrett, Alena Zíková, Michael Boshart, Jean-Charles Portais, Frédéric Bringaud
Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline. PLoS pathogens 17 (3) (2021)
Pavla Perlíková, Anna Krajczyk, Eva Doleželová, Martina Slapničková, Nemanja Milisavljevic, Lenka Poštová Slavětínská, Eva Tloušt'ová, Soňa Gurská, Petr Džubák, Marián Hajdúch, Alena Zíková, Michal Hocek
Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS infectious diseases 7 (4) (2021)
Victor Tobiasson, Ondřej Gahura, Shintaro Aibara, Rozbeh Baradaran, Alena Zíková, Alexey Amunts
Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit. The EMBO journal 40 (6) (2021)
Ondřej Gahura, Carolina Hierro-Yap, Alena Zíková
Redesigned and reversed: architectural and functional oddities of the trypanosomal ATP synthase. Parasitology 148 (10) (2021)
Martin Zoltner, Gustavo D Campagnaro, Gergana Taleva, Alana Burrell, Michela Cerone, Ka-Fai Leung, Fiona Achcar, David Horn, Sue Vaughan, Catarina Gadelha, Alena Zíková, Michael P Barrett, Harry P de Koning, Mark C Field
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes. The Journal of biological chemistry 295 (24) (2020)
Eva Doleželová, Michaela Kunzová, Mario Dejung, Michal Levin, Brian Panicucci, Clément Regnault, Christian J Janzen, Michael P Barrett, Falk Butter, Alena Zíková
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS biology 18 (6) (2020)
Eva Doleželová, David Terán, Ondřej Gahura, Zuzana Kotrbová, Michaela Procházková, Dianne Keough, Petr Špaček, Dana Hocková, Luke Guddat, Alena Zíková
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery. PLoS neglected tropical diseases 12 (2) (2018)
Michaela Procházková, Brian Panicucci, Alena Zíková
Cultured bloodstream Trypanosoma brucei adapt to life without mitochondrial translation release factor 1. Scientific reports 8 (1) (2018)
Alena Zíková, Zdeněk Verner, Anna Nenarokova, Paul A M Michels, Julius Lukeš
A paradigm shift: The mitoproteomes of procyclic and bloodstream Trypanosoma brucei are comparably complex. PLoS pathogens 13 (12) (2017)
Brian Panicucci, Ondřej Gahura, Alena Zíková
Trypanosoma brucei TbIF1 inhibits the essential F1-ATPase in the infectious form of the parasite. PLoS neglected tropical diseases 11 (4) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Alena Zíková