Luke W Guddat (Luke Guddat)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 56

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Journal of medicinal chemistry

Nature

Nature communications

The University of Queensland

Saint Vincent's Institute of Medical Research (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Queensland Jan 01 2019

Australia

Professor :: School of Chemistry and Molecular Biosciences

The University of Queensland Jan 01 2006 - Dec 31 2009

Australia

Senior Lecturer :: School of Chemistry and Molecular Biosciences

The University of Queensland Jan 01 2002 - Dec 31 2005

Australia

Lecturer :: School of Chemistry and Molecular Biosciences

The University of Queensland Jan 01 1999 - Dec 31 2001

Australia

Departmental Fellow :: Department of Biochemistry

Harrington Cancer Center

United States

Research Scientist

University of Utah

United States

Research Scientist

Education History

Saint Vincent's Institute of Medical Research

Australia

PHD

Publications

Yuying Zhang, Yuezheng Lai, Shan Zhou, Ting Ran, Yue Zhang, Ziqing Zhao, Ziyan Feng, Long Yu, Jinxu Xu, Kun Shi, Jianyun Wang, Yu Pang, Liang Li, Hongming Chen, Luke W Guddat, Yan Gao, Fengjiang Liu, Zihe Rao, Hongri Gong
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature (2024)
Yuying Zhang, Yuezheng Lai, Shan Zhou, Ting Ran, Yue Zhang, Ziqing Zhao, Ziyan Feng, Long Yu, Jinxu Xu, Kun Shi, Jianyun Wang, Yu Pang, Liang Li, Hongming Chen, Luke W Guddat, Yan Gao, Fengjiang Liu, Zihe Rao, Hongri Gong
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature 631 (8020) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology 31 (7) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology 31 (7) (2024)
Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiu-Na Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang
Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD. Science advances 10 (12) (2024)
Tabassum Khair Barbhuiya, Sam Beard, Esha T Shah, Steven Mason, Emma Bolderson, Ken O'Byrne, Luke W Guddat, Derek J Richard, Mark N Adams, Neha S Gandhi
Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators. ACS omega 9 (7) (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology (2024)
Tabassum Khair Barbhuiya, Sam Beard, Esha T Shah, Steven Mason, Emma Bolderson, Ken O'Byrne, Luke W Guddat, Derek J Richard, Mark N Adams, Neha S Gandhi
Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators. ACS omega 9 (7) (2024)
Yuying Zhang, Yuezheng Lai, Shan Zhou, Ting Ran, Yue Zhang, Ziqing Zhao, Ziyan Feng, Long Yu, Jinxu Xu, Kun Shi, Jianyun Wang, Yu Pang, Liang Li, Hongming Chen, Luke W Guddat, Yan Gao, Fengjiang Liu, Zihe Rao, Hongri Gong
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature (2024)
Quan Wang, Tao Wang, Lin Cao, An Mu, Sheng Fu, Peipei Wang, Yan Gao, Wenxin Ji, Zhenyu Liu, Zhanqiang Du, Luke W Guddat, Wenchi Zhang, Shuang Li, Xuemei Li, Zhiyong Lou, Xiangxi Wang, Zhongyu Hu, Zihe Rao
Inherent symmetry and flexibility in hepatitis B virus subviral particles. Science (New York, N.Y.) 385 (6714) (2024)
Yuying Zhang, Yuezheng Lai, Shan Zhou, Ting Ran, Yue Zhang, Ziqing Zhao, Ziyan Feng, Long Yu, Jinxu Xu, Kun Shi, Jianyun Wang, Yu Pang, Liang Li, Hongming Chen, Luke W Guddat, Yan Gao, Fengjiang Liu, Zihe Rao, Hongri Gong
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature 631 (8020) (2024)
Yinan Wang, Shan Gao, Fangyu Wu, Yicheng Gong, Nengjiang Mu, Chuancun Wei, Chengyao Wu, Jun Wang, Ning Yan, Huifang Yang, Yifan Zhang, Jiayi Liu, Zeyu Wang, Xiu-Na Yang, Sin Man Lam, Guanghou Shui, Siyuan Li, Lintai Da, Luke W Guddat, Zihe Rao, Lu Zhang
Cryo-EM structures of a mycobacterial ABC transporter that mediates rifampicin resistance. Proceedings of the National Academy of Sciences of the United States of America 121 (37) (2024)
Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiu-Na Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang
Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD. Science advances 10 (12) (2024)
Yuying Zhang, Yuezheng Lai, Shan Zhou, Ting Ran, Yue Zhang, Ziqing Zhao, Ziyan Feng, Long Yu, Jinxu Xu, Kun Shi, Jianyun Wang, Yu Pang, Liang Li, Hongming Chen, Luke W Guddat, Yan Gao, Fengjiang Liu, Zihe Rao, Hongri Gong
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature 631 (8020) (2024)
Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiu-Na Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang
Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD. Science advances 10 (12) (2024)
Jitendra Kumar Meena, Jarey H Wang, Nicholas J Neill, Dianne Keough, Nagireddy Putluri, Panagiostis Katsonis, Amanda M Koire, Hyemin Lee, Elizabeth A Bowling, Siddhartha Tyagi, Mayra Orellana, Rocio Dominguez-Vidana, Heyuan Li, Kenneth Eagle, Charles H Danan, Hsiang-Ching Chung, Andrew D Yang, William Wu, Sarah J Kurley, Brian M Ho, Joseph R Zoeller, Calla M Olson, Kristen L Meerbrey, Olivier Lichtarge, Arun Sreekumar, Clifford C Dacso, Luke W Guddat, Dominik Rejman, Dana Hocková, Zlatko Janeba, Lukas M Simon, Charles Y Lin, Monica C Pillon, Thomas F Westbrook
MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer. Cancer discovery (2024)
Xiaolin Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Zhenli Lin, Yao Zhao, Xiaoting Zhou, Yan Gao, Shan Sun, Xiu-Na Yang, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality. Nature structural & molecular biology 31 (7) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry 67 (9) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry 67 (9) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry 67 (9) (2024)
Dianne T Keough, Magdalena Petrová, Gordon King, Michal Kratochvíl, Radek Pohl, Eva Doleželová, Alena Zíková, Luke W Guddat, Dominik Rejman
Development of Prolinol Containing Inhibitors of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design. Journal of medicinal chemistry (2024)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Yan Cheng, Thierry Lonhienne, Mario D Garcia, Craig M Williams, Haruhiko Fuwa, Luke W Guddat
Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase. Journal of agricultural and food chemistry (2023)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Jingxi Liang, Fengjiang Liu, Biao Yu, Wei Shangguan, Tianyu Hu, Shule Wang, Xiaolin Yang, Zhiqi Xiong, Xiu-Na Yang, Luke W Guddat, Biao Yu, Zihe Rao, Bing Zhang
Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proceedings of the National Academy of Sciences of the United States of America 120 (35) (2023)
Xue-Wen Sun, Yixuan Liu, Xiaofang Wang, Hao-Ran Li, Xin Lin, Jin-Yin Tang, Qing Xu, Kylie A Agnew-Francis, James A Fraser, Zhi-Juan Sun, Luke W Guddat, Jian-Guo Wang
Structure-activity relationships of bensulfuron methyl and its derivatives as novel agents against drug-resistant Candida auris. Chemical biology & drug design (2023)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke W Guddat, Hongli Chen, Lei-Ke Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang
Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nature communications 14 (1) (2023)
Zhanqiang Du, Xiaoting Zhou, Yuezheng Lai, Jinxu Xu, Yuying Zhang, Shan Zhou, Ziyan Feng, Long Yu, Yanting Tang, Weiwei Wang, Lu Yu, Changlin Tian, Ting Ran, Hongming Chen, Luke W Guddat, Fengjiang Liu, Yan Gao, Zihe Rao, Hongri Gong
Structure of the human respiratory complex II. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Yao Zhao, Yan Zhu, Xiang Liu, Zhenming Jin, Yinkai Duan, Qi Zhang, Chengyao Wu, Lu Feng, Xiaoyu Du, Jinyi Zhao, Maolin Shao, Bing Zhang, Xiu-Na Yang, Li-Jie Wu, Xiaoyun Ji, Luke W Guddat, Kailin Yang, Zihe Rao, Haitao Yang
Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America 119 (16) (2022)
Shan Sun, Yan Gao, Xiaolin Yang, Xiu-Na Yang, Tianyu Hu, Jingxi Liang, Zhiqi Xiong, Yuting Ran, Pengxuan Ren, Fang Bai, Luke W Guddat, Haitao Yang, Zihe Rao, Bing Zhang
Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein & cell (2022)
Tomáš Klejch, Dianne T Keough, Gordon King, Eva Doleželová, Michal Česnek, Miloš Buděšínský, Alena Zíková, Zlatko Janeba, Luke W Guddat, Dana Hocková
Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases. Journal of medicinal chemistry 65 (5) (2022)
Thierry Lonhienne, Yan Cheng, Mario D Garcia, Shu Hong Hu, Yu Shang Low, Haruhiko Fuwa, Craig M Williams, Luke W Guddat
Structural basis of resistance to herbicides that target acetohydroxyacid synthase. Nature communications 13 (1) (2022)
Xin Lin, Julia L Kurz, Khushboo M Patel, Shun Jie Wun, Waleed M Hussein, Thierry Lonhienne, Nicholas P West, Ross P McGeary, Gerhard Schenk, Luke W Guddat
Discovery of a Pyrimidinedione Derivative with Potent Inhibitory Activity against Mycobacterium tuberculosis Ketol-Acid Reductoisomerase. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (9) (2021)
Xiaoting Zhou, Yan Gao, Weiwei Wang, Xiaolin Yang, Xiu-Na Yang, Fengjiang Liu, Yanting Tang, Sin Man Lam, Guanghou Shui, Lu Yu, Changlin Tian, Luke W Guddat, Quan Wang, Zihe Rao, Hongri Gong
Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster. Proceedings of the National Academy of Sciences of the United States of America 118 (15) (2021)
Shan Zhou, Weiwei Wang, Xiaoting Zhou, Yuying Zhang, Yuezheng Lai, Yanting Tang, Jinxu Xu, Dongmei Li, Jianping Lin, Xiaolin Yang, Ting Ran, Hongming Chen, Luke W Guddat, Quan Wang, Yan Gao, Zihe Rao, Hongri Gong
Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates. eLife 10 (2021)
Weiwei Wang, Yan Gao, Yanting Tang, Xiaoting Zhou, Yuezheng Lai, Shan Zhou, Yuying Zhang, Xiuna Yang, Fengjiang Liu, Luke W Guddat, Quan Wang, Zihe Rao, Hongri Gong
Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels. Nature communications 12 (1) (2021)
Hongri Gong, Yan Gao, Xiaoting Zhou, Yu Xiao, Weiwei Wang, Yanting Tang, Shan Zhou, Yuying Zhang, Wenxin Ji, Lu Yu, Changlin Tian, Sin Man Lam, Guang-Hou Shui, Luke W Guddat, Luet-Lok Wong, Quan Wang, Zihe Rao
Author Correction: Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF. Nature communications 12 (1) (2021)
Ajit Kandale, Khushboo Patel, Waleed M Hussein, Shun Jie Wun, Shan Zheng, Lendl Tan, Nicholas P West, Gerhard Schenk, Luke W Guddat, Ross P McGeary
Analogues of the Herbicide, N-Hydroxy-N-isopropyloxamate, Inhibit Mycobacterium tuberculosis Ketol-Acid Reductoisomerase and Their Prodrugs Are Promising Anti-TB Drug Leads. Journal of medicinal chemistry 64 (3) (2021)
Dianne T Keough, Shun Jie Wun, Ondřej Baszczyňski, Wai Soon Eng, Petr Špaček, Santosh Panjikar, Lieve Naesens, Radek Pohl, Dominik Rejman, Dana Hocková, Richard L Ferrero, Luke W Guddat
Helicobacter pylori Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections. Journal of medicinal chemistry 64 (9) (2021)
Marcelo Monteiro Pedroso, David W Waite, Okke Melse, Liam Wilson, Nataša Mitić, Ross P McGeary, Iris Antes, Luke W Guddat, Philip Hugenholtz, Haruhiko Fuwa
Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse. Protein & cell 11 (8) (2021)
Tenuun Bayaraa, Julia L Kurz, Khushboo M Patel, Waleed M Hussein, Jessica K Bilyj, Nicholas P West, Gerhard Schenk, Ross P McGeary, Luke W Guddat
Discovery, Synthesis and Evaluation of a Ketol-Acid Reductoisomerase Inhibitor. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (41) (2020)
Hongri Gong, Yan Gao, Xiaoting Zhou, Yu Xiao, Weiwei Wang, Yanting Tang, Shan Zhou, Yuying Zhang, Wenxin Ji, Lu Yu, Changlin Tian, Sin Man Lam, Guang-Hou Shui, Luke W Guddat, Luet-Lok Wong, Quan Wang, Zihe Rao
Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF. Nature communications 11 (1) (2020)
Xiaobo Chen, Jiayue Chen, Bing Yan, Wei Zhang, Luke W Guddat, Xiang Liu, Zihe Rao
Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria. Proceedings of the National Academy of Sciences of the United States of America 117 (28) (2020)
Fengjiang Liu, Jingxi Liang, Bing Zhang, Yan Gao, Xiuna Yang, Tianyu Hu, Haitao Yang, Wenqing Xu, Luke W Guddat, Zihe Rao
Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Science advances 6 (44) (2020)
Lu Zhang, Yao Zhao, Yan Gao, Li-Jie Wu, Ruogu Gao, Qi Zhang, Yinan Wang, Chengyao Wu, Fangyu Wu, Sudagar S Gurcha, Natacha Veerapen, Sarah M Batt, Wei Zhao, Ling Qin, Xiuna Yang, Manfu Wang, Yan Zhu, Bing Zhang, Lijun Bi, Xian'en Zhang, Haitao Yang, Luke W Guddat, Wenqing Xu, Quan Wang, Jun Li, Gurdyal S Besra, Zihe Rao
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science (New York, N.Y.) 368 (6496) (2020)
Yan Gao, Liming Yan, Yucen Huang, Fengjiang Liu, Yao Zhao, Lin Cao, Tao Wang, Qianqian Sun, Zhenhua Ming, Lianqi Zhang, Ji Ge, Litao Zheng, Ying Zhang, Haofeng Wang, Yan Zhu, Chen Zhu, Tianyu Hu, Tian Hua, Bing Zhang, Xiuna Yang, Jun Li, Haitao Yang, Zhijie Liu, Wenqing Xu, Luke W Guddat, Quan Wang, Zhiyong Lou, Zihe Rao
Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science (New York, N.Y.) 368 (6492) (2020)
Kylie A Agnew-Francis, Yucheng Tang, Xin Lin, Yu Shang Low, Shun Jie Wun, Andy Kuo, S M A Sayeed Ibn Elias, Thierry Lonhienne, Nicholas D Condon, Bruna N A S Pimentel, Carlos E Vergani, Maree T Smith, James A Fraser, Craig M Williams, Luke W Guddat
Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris. ACS infectious diseases 6 (11) (2020)
Thierry Lonhienne, Yu Shang Low, Mario D Garcia, Tristan Croll, Yan Gao, Quan Wang, Lou Brillault, Craig M Williams, James A Fraser, Ross P McGeary, Nicholas P West, Michael J Landsberg, Zihe Rao, Haruhiko Fuwa, Luke W Guddat
Structures of fungal and plant acetohydroxyacid synthases. Nature 586 (7828) (2020)
David A Terán, Eva Doleželová, Dianne T Keough, Dana Hocková, Alena Zíková, Luke W Guddat
Crystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP. The FEBS journal 286 (23) (2019)
Khushboo M Patel, David Teran, Shan Zheng, Ajit Kandale, Mario Garcia, You Lv, Mark A Schembri, Ross P McGeary, Gerhard Schenk, Luke W Guddat
Crystal Structures of Staphylococcus aureus Ketol-Acid Reductoisomerase in Complex with Two Transition State Analogues that Have Biocidal Activity. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (72) (2017)
Dianne T Keough, Dominik Rejman, Radek Pohl, Eva Zborníková, Dana Hocková, Tristan Croll, Michael D Edstein, Geoff W Birrell, Marina Chavchich, Lieve M J Naesens, Gregory K Pierens, Ian M Brereton, Luke W Guddat
Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics. ACS chemical biology 13 (1) (2017)
Thierry Lonhienne, Amanda Nouwens, Craig M Williams, James A Fraser, Yu-Ting Lee, Nicholas P West, Luke W Guddat
Commercial Herbicides Can Trigger the Oxidative Inactivation of Acetohydroxyacid Synthase. Angewandte Chemie (International ed. in English) 55 (13) (2016)

Luke W Guddat.css-eqlu8i{font-size:small;padding-left:4px;} (Luke Guddat)

Publication Activity (10 Years)

Top Topics

Top Venues

Luke W Guddat (Luke Guddat)