Alexandra C Newton

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 19

Top Venues

The Biochemical journal

bioRxiv : the preprint server for biology

Science signaling

IUBMB life

University of California San Diego

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California San Diego

United States

Distinguished Professor :: Pharmacology

Publications

Stefanie J Hodapp, Nathan Gravel, Natarajan Kannan, Alexandra C Newton
Cancer-associated mutations in protein kinase C theta are loss-of-function. The Biochemical journal 481 (12) (2024)
Qi Su, Jing Zhang, Wei Lin, Jin-Fan Zhang, Alexandra C Newton, Sohum Mehta, Jing Yang, Jin Zhang
Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC. bioRxiv : the preprint server for biology (2024)
Stefanie J Hodapp, Nathan Gravel, Natarajan Kannan, Alexandra C Newton
Cancer-associated mutations in protein kinase C theta are loss-of-function. The Biochemical journal 481 (12) (2024)
Stefanie J Hodapp, Nathan Gravel, Natarajan Kannan, Alexandra C Newton
Cancer-associated mutations in protein kinase C theta are loss-of-function. The Biochemical journal 481 (12) (2024)
Qi Su, Jing Zhang, Wei Lin, Jin-Fan Zhang, Alexandra C Newton, Sohum Mehta, Jing Yang, Jin Zhang
Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC. bioRxiv : the preprint server for biology (2024)
Qi Su, Jing Zhang, Wei Lin, Jin-Fan Zhang, Alexandra C Newton, Sohum Mehta, Jing Yang, Jin Zhang
Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC. bioRxiv : the preprint server for biology (2024)
Stefanie J Hodapp, Nathan Gravel, Natarajan Kannan, Alexandra C Newton
Cancer-associated mutations in protein kinase C theta are loss-of-function. The Biochemical journal 481 (12) (2024)
Alexander C Jones, Alexandr P Kornev, Jui-Hung Weng, Gerard Manning, Susan S Taylor, Alexandra C Newton
Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration. bioRxiv : the preprint server for biology (2023)
Victoria Patten, Elyse S Fischer, Patrick Penndorf, Alexandra C Newton
Tatenda Murigo: A passionate advocate for science in Africa (June 17, 2000-July 14, 2023). IUBMB life (2023)
Gema Lordén, Jacob M Wozniak, Kim Doré, Lara E Dozier, Chelsea Cates-Gatto, Gentry N Patrick, David J Gonzalez, Amanda J Roberts, Rudolph E Tanzi, Alexandra C Newton
Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model. Nature communications 13 (1) (2022)
Caila A Pilo, Timothy R Baffi, Alexandr P Kornev, Maya T Kunkel, Mario Malfavon, Dong-Hui Chen, Leigh-Ana Rossitto, Daniel X Chen, Liang-Chin Huang, Cheryl Longman, Natarajan Kannan, Wendy H Raskind, David J Gonzalez, Susan S Taylor, George Gorrie, Alexandra C Newton
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition. Science signaling 15 (753) (2022)
Gema Lordén, Alexandra C Newton
Conventional protein kinase C in the brain: repurposing cancer drugs for neurodegenerative treatment? Neuronal signaling 5 (4) (2021)
Timothy R Baffi, Gema Lordén, Jacob M Wozniak, Andreas Feichtner, Wayland Yeung, Alexandr P Kornev, Charles C King, Jason C Del Rio, Ameya J Limaye, Julijus Bogomolovas, Christine M Gould, Ju Chen, Eileen J Kennedy, Natarajan Kannan, David J Gonzalez, Eduard Stefan, Susan S Taylor, Alexandra C Newton
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science signaling 14 (678) (2021)
Alexander C Jones, Susan S Taylor, Alexandra C Newton, Alexandr P Kornev
Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes. IUBMB life 72 (12) (2020)
Alexandra C Newton
Protein kinases in tune. IUBMB life 71 (6) (2019)
Ksenya Cohen Katsenelson, Joshua D Stender, Agnieszka T Kawashima, Gema Lordén, Satoshi Uchiyama, Victor Nizet, Christopher K Glass, Alexandra C Newton
PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. eLife 8 (2019)
Taketoshi Kajimoto, Alisha D Caliman, Irene S Tobias, Taro Okada, Caila A Pilo, An-Angela N Van, James Andrew McCammon, Shun-Ichi Nakamura, Alexandra C Newton
Activation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter. Science signaling 12 (562) (2019)
Julia A Callender, Yimin Yang, Gema Lordén, Natalie L Stephenson, Alexander C Jones, John Brognard, Alexandra C Newton
Protein kinase Cα gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulation. Proceedings of the National Academy of Sciences of the United States of America 115 (24) (2018)
Nileeka Balasuriya, Maya T Kunkel, Xuguang Liu, Kyle K Biggar, Shawn S-C Li, Alexandra C Newton, Patrick O'Donoghue
Genetic code expansion and live cell imaging reveal that Thr-308 phosphorylation is irreplaceable and sufficient for Akt1 activity. The Journal of biological chemistry 293 (27) (2018)

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Publication Activity (10 Years)

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Alexandra C Newton