Eduard Stefan

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 35

Top Venues

Nature structural & molecular biology

Nature communications

Cellular and molecular life sciences : CMLS

eLife

Universität Innsbruck

Freie Universität Berlin (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universität Innsbruck

Austria

Group leader :: Institut of Biochemistry

Université de Montréal

Canada

Postdoc :: Département de biochimie

Freie Universität Berlin

Germany

PhD Student

Universität Wien

Austria

Master Student :: Institute of Pharmacology

Education History

Freie Universität Berlin

Germany

PHD :: Leibniz Institute of Molecular Pharmacology

Universität Wien

Austria

MSC :: Vienna Biocenter

Publications

Andreas Feichtner, Florian Enzler, Valentina Kugler, Katharina Hoppe, Sophia Mair, Leopold Kremser, Herbert H Lindner, Roland G Huber, Ulrich Stelzl, Eduard Stefan, Omar Torres-Quesada
Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-protein interactions. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Valentina Kugler, Selina Schwaighofer, Andreas Feichtner, Florian Enzler, Jakob Fleischmann, Sophie Strich, Sarah Schwarz, Rebecca Wilson, Philipp Tschaikner, Jakob Troppmair, Veronika Sexl, Pascal Meier, Teresa Kaserer, Eduard Stefan
Impact of protein and small molecule interactions on kinase conformations. eLife 13 (2024)
Valentina Kugler, Selina Schwaighofer, Andreas Feichtner, Florian Enzler, Jakob Fleischmann, Sophie Strich, Sarah Schwarz, Rebecca Wilson, Philipp Tschaikner, Jakob Troppmair, Veronika Sexl, Pascal Meier, Teresa Kaserer, Eduard Stefan
Impact of protein and small molecule interactions on kinase conformations. eLife 13 (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology (2024)
Andreas Feichtner, Florian Enzler, Valentina Kugler, Katharina Hoppe, Sophia Mair, Leopold Kremser, Herbert H Lindner, Roland G Huber, Ulrich Stelzl, Eduard Stefan, Omar Torres-Quesada
Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-protein interactions. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Laura Rinaldi, Rossella Delle Donne, Bruno Catalanotti, Omar Torres-Quesada, Florian Enzler, Federica Moraca, Robert Nisticò, Francesco Chiuso, Sonia Piccinin, Verena Bachmann, Herbert H Lindner, Corrado Garbi, Antonella Scorziello, Nicola Antonino Russo, Matthis Synofzik, Ulrich Stelzl, Lucio Annunziato, Eduard Stefan, Antonio Feliciello
Author Correction: Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Nature communications 15 (1) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology 31 (4) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology 31 (4) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology 31 (4) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology (2024)
Andreas Feichtner, Florian Enzler, Valentina Kugler, Katharina Hoppe, Sophia Mair, Leopold Kremser, Herbert H Lindner, Roland G Huber, Ulrich Stelzl, Eduard Stefan, Omar Torres-Quesada
Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-protein interactions. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology 31 (4) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology 31 (4) (2024)
Laura Rinaldi, Rossella Delle Donne, Bruno Catalanotti, Omar Torres-Quesada, Florian Enzler, Federica Moraca, Robert Nisticò, Francesco Chiuso, Sonia Piccinin, Verena Bachmann, Herbert H Lindner, Corrado Garbi, Antonella Scorziello, Nicola Antonino Russo, Matthis Synofzik, Ulrich Stelzl, Lucio Annunziato, Eduard Stefan, Antonio Feliciello
Author Correction: Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Nature communications 15 (1) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology (2024)
Andreas Feichtner, Florian Enzler, Valentina Kugler, Katharina Hoppe, Sophia Mair, Leopold Kremser, Herbert H Lindner, Roland G Huber, Ulrich Stelzl, Eduard Stefan, Omar Torres-Quesada
Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-protein interactions. Cellular and molecular life sciences : CMLS 81 (1) (2024)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Ziwei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Nature structural & molecular biology 31 (4) (2024)
Valentina Kugler, Selina Schwaighofer, Andreas Feichtner, Florian Enzler, Jakob Fleischmann, Sophie Strich, Sarah Schwarz, Rebecca Wilson, Philipp Tschaikner, Jakob Troppmair, Veronika Sexl, Pascal Meier, Teresa Kaserer, Eduard Stefan
Impact of protein and small molecule interactions on kinase conformations. eLife 13 (2024)
Christina S Moesslacher, Elisabeth Auernig, Jonathan Woodsmith, Andreas Feichtner, Evelyne Jany-Luig, Stefanie Jehle, Josephine M Worseck, Christian L Heine, Eduard Stefan, Ulrich Stelzl
Missense variant interaction scanning reveals a critical role of the FERM domain for tumor suppressor protein NF2 conformation and function. Life science alliance 6 (8) (2023)
Francesco Costacurta, Andrea Dodaro, David Bante, Helge Schoeppe, Bernhard Sprenger, Seyed Arad Moghadasi, Jakob Fleischmann, Matteo Pavan, Davide Bassani, Silvia Menin, Stefanie Rauch, Laura Krismer, Anna Sauerwein, Anne Heberle, Toni Rabensteiner, Joses Wei Hao Ho, Reuben Stewart Harris, Eduard Stefan, Rainer Schneider, Teresa Kaserer, Stefano Moro, Dorothee von Laer, Emmanuel Heilmann
A comprehensive study of SARS-CoV-2 main protease (M pro ) inhibitor-resistant mutants selected in a VSV-based system. bioRxiv : the preprint server for biology (2023)
Jakob Fleischmann, Selina Schwaighofer, Louis De Falco, Florian Enzler, Andreas Feichtner, Valentina Kugler, Philipp Tschaikner, Roland G Huber, Eduard Stefan
Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities. PNAS nexus 2 (6) (2023)
Valentina Kugler, Andreas Lieb, Nathan Guerin, Bruce R Donald, Eduard Stefan, Teresa Kaserer
Disruptor: Computational identification of oncogenic mutants disrupting protein-protein and protein-DNA interactions. Communications biology 6 (1) (2023)
Nicholas Hoppe, Simone Harrison, Sun-Hee Hwang, Zi-Wei Chen, Masha Karelina, Ishan Deshpande, Carl-Mikael Suomivuori, Vivek R Palicharla, Samuel P Berry, Philipp Tschaikner, Dominik Regele, Douglas F Covey, Eduard Stefan, Debora S Marks, Jeremy F Reiter, Ron O Dror, Alex S Evers, Saikat Mukhopadhyay, Aashish Manglik
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. bioRxiv : the preprint server for biology (2023)
Omar Torres-Quesada, Carolina Doerrier, Sophie Strich, Erich Gnaiger, Eduard Stefan
Physiological Cell Culture Media Tune Mitochondrial Bioenergetics and Drug Sensitivity in Cancer Cell Models. Cancers 14 (16) (2022)
Andreas Feichtner, Valentina Kugler, Selina Schwaighofer, Thomas Nuener, Jakob Fleischmann, Eduard Stefan
Tracking mutation and drug-driven alterations of oncokinase conformations. Memo 15 (2) (2022)
Jakob Fleischmann, Andreas Feichtner, Louis De Falco, Valentina Kugler, Selina Schwaighofer, Roland G Huber, Eduard Stefan
Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico. Biomolecules 11 (4) (2021)
Timothy R Baffi, Gema Lordén, Jacob M Wozniak, Andreas Feichtner, Wayland Yeung, Alexandr P Kornev, Charles C King, Jason C Del Rio, Ameya J Limaye, Julijus Bogomolovas, Christine M Gould, Ju Chen, Eileen J Kennedy, Natarajan Kannan, David J Gonzalez, Eduard Stefan, Susan S Taylor, Alexandra C Newton
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science signaling 14 (678) (2021)
Florian Enzler, Philipp Tschaikner, Rainer Schneider, Eduard Stefan
KinCon: Cell-based recording of full-length kinase conformations. IUBMB life 72 (6) (2020)
Johanna E Mayrhofer, Florian Enzler, Andreas Feichtner, Ruth Röck, Jakob Fleischmann, Andrea Raffeiner, Philipp Tschaikner, Egon Ogris, Roland G Huber, Markus Hartl, Rainer Schneider, Jakob Troppmair, Omar Torres-Quesada, Eduard Stefan
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies. Proceedings of the National Academy of Sciences of the United States of America 117 (49) (2020)
Philipp Tschaikner, Florian Enzler, Omar Torres-Quesada, Pia Aanstad, Eduard Stefan
Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium. Cells 9 (1) (2020)
Laura Rinaldi, Rossella Delle Donne, Bruno Catalanotti, Omar Torres-Quesada, Florian Enzler, Federica Moraca, Robert Nisticò, Francesco Chiuso, Sonia Piccinin, Verena Bachmann, Herbert H Lindner, Corrado Garbi, Antonella Scorziello, Nicola Antonino Russo, Matthis Synofzik, Ulrich Stelzl, Lucio Annunziato, Eduard Stefan, Antonio Feliciello
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system. Nature communications 10 (1) (2019)
Ruth Röck, Johanna E Mayrhofer, Omar Torres-Quesada, Florian Enzler, Andrea Raffeiner, Philipp Raffeiner, Andreas Feichtner, Roland G Huber, Shohei Koide, Susan S Taylor, Jakob Troppmair, Eduard Stefan
BRAF inhibitors promote intermediate BRAF(V600E) conformations and binary interactions with activated RAS. Science advances 5 (8) (2019)
Monia Porpora, Simona Sauchella, Laura Rinaldi, Rossella Delle Donne, Maria Sepe, Omar Torres-Quesada, Daniela Intartaglia, Corrado Garbi, Luigi Insabato, Margherita Santoriello, Verena A Bachmann, Matthis Synofzik, Herbert H Lindner, Ivan Conte, Eduard Stefan, Antonio Feliciello
Counterregulation of cAMP-directed kinase activities controls ciliogenesis. Nature communications 9 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Eduard Stefan