Natarajan Kannan

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 41

Top Topics

Molecular Dynamics Simulations

Machine Learning

Top Venues

Bioinformatics (Oxford, England)

bioRxiv : the preprint server for biology

Science advances

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Zhongliang Zhou, Wayland Yeung, Saber Soleymani, Nathan Gravel, Mariah Salcedo, Sheng Li, Natarajan Kannan
Using explainable machine learning to uncover the kinase-substrate interaction landscape. Bioinformatics (Oxford, England) 40 (2) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Zhongliang Zhou, Wayland Yeung, Saber Soleymani, Nathan Gravel, Mariah Salcedo, Sheng Li, Natarajan Kannan
Using explainable machine learning to uncover the kinase-substrate interaction landscape. Bioinformatics (Oxford, England) 40 (2) (2024)
Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan
Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways. NPJ systems biology and applications 10 (1) (2024)
Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan
Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways. NPJ systems biology and applications 10 (1) (2024)
Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan
Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways. NPJ systems biology and applications 10 (1) (2024)
Zhongliang Zhou, Wayland Yeung, Saber Soleymani, Nathan Gravel, Mariah Salcedo, Sheng Li, Natarajan Kannan
Using explainable machine learning to uncover the kinase-substrate interaction landscape. Bioinformatics (Oxford, England) 40 (2) (2024)
Zhongliang Zhou, Wayland Yeung, Saber Soleymani, Nathan Gravel, Mariah Salcedo, Sheng Li, Natarajan Kannan
Using explainable machine learning to uncover the kinase-substrate interaction landscape. Bioinformatics (Oxford, England) 40 (2) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan
Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways. NPJ systems biology and applications 10 (1) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan
Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways. NPJ systems biology and applications 10 (1) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Zhongliang Zhou, Wayland Yeung, Saber Soleymani, Nathan Gravel, Mariah Salcedo, Sheng Li, Natarajan Kannan
Using explainable machine learning to uncover the kinase-substrate interaction landscape. Bioinformatics (Oxford, England) 40 (2) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Aarya Venkat, Grace Watterson, Dominic P Byrne, Brady O'Boyle, Safal Shrestha, Nathan Gravel, Emma E Fairweather, Leonard A Daly, Claire Bunn, Wayland Yeung, Ishan Aggarwal, Samiksha Katiyar, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases. bioRxiv : the preprint server for biology (2023)
Zhongliang Zhou, Wayland Yeung, Nathan Gravel, Mariah Salcedo, Saber Soleymani, Sheng Li, Natarajan Kannan
Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions. Bioinformatics (Oxford, England) 39 (2) (2023)
Zhongliang Zhou, Wayland Yeung, Nathan Gravel, Mariah Salcedo, Saber Soleymani, Sheng Li, Natarajan Kannan
Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions. Bioinformatics (Oxford, England) 39 (2) (2023)
Yanxiang Meng, Sarah E Garnish, Katherine A Davies, Katrina A Black, Andrew P Leis, Christopher R Horne, Joanne M Hildebrand, Hanadi Hoblos, Cheree Fitzgibbon, Samuel N Young, Toby Dite, Laura F Dagley, Aarya Venkat, Natarajan Kannan, Akiko Koide, Shohei Koide, Alisa Glukhova, Peter E Czabotar, James G Murphy
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization. Nature communications 14 (1) (2023)
Hipólito Nicolás Cuesta-Hernández, Julia Contreras, Pablo Soriano-Maldonado, Jana Sánchez-Wandelmer, Wayland Yeung, Ana Martín-Hurtado, Inés G Muñoz, Natarajan Kannan, Marta Llimargas, Javier Muñoz, Iván Plaza-Menacho
An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function. Nature communications 14 (1) (2023)
Aarya Venkat, Grace Watterson, Dominic P Byrne, Brady O'Boyle, Safal Shrestha, Nathan Gravel, Emma E Fairweather, Leonard A Daly, Claire Bunn, Wayland Yeung, Ishan Aggarwal, Samiksha Katiyar, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases. eLife 12 (2023)
Zhongliang Zhou, Wayland Yeung, Nathan Gravel, Mariah Salcedo, Saber Soleymani, Sheng Li, Natarajan Kannan
Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions. Bioinformatics (Oxford, England) 39 (2) (2023)
Zhongliang Zhou, Wayland Yeung, Nathan Gravel, Mariah Salcedo, Saber Soleymani, Sheng Li, Natarajan Kannan
Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions. Bioinformatics (Oxford, England) 39 (2) (2023)
Caila A Pilo, Timothy R Baffi, Alexandr P Kornev, Maya T Kunkel, Mario Malfavon, Dong-Hui Chen, Leigh-Ana Rossitto, Daniel X Chen, Liang-Chin Huang, Cheryl Longman, Natarajan Kannan, Wendy H Raskind, David J Gonzalez, Susan S Taylor, George Gorrie, Alexandra C Newton
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition. Science signaling 15 (753) (2022)
Rahil Taujale, Saber Soleymani, Amitabh Priyadarshi, Aarya Venkat, Wayland Yeung, Krzysztof J Kochut, Natarajan Kannan
GTXplorer: A portal to navigate and visualize the evolutionary information encoded in fold a glycosyltransferases. Glycobiology (2021)
Timothy R Baffi, Gema Lordén, Jacob M Wozniak, Andreas Feichtner, Wayland Yeung, Alexandr P Kornev, Charles C King, Jason C Del Rio, Ameya J Limaye, Julijus Bogomolovas, Christine M Gould, Ju Chen, Eileen J Kennedy, Natarajan Kannan, David J Gonzalez, Eduard Stefan, Susan S Taylor, Alexandra C Newton
mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif. Science signaling 14 (678) (2021)
Rahil Taujale, Zhongliang Zhou, Wayland Yeung, Kelley W Moremen, Sheng Li, Natarajan Kannan
Mapping the glycosyltransferase fold landscape using interpretable deep learning. Nature communications 12 (1) (2021)
Safal Shrestha, Samiksha Katiyar, Carlos E Sanz-Rodriguez, Nolan R Kemppinen, Hyun W Kim, Renuka Kadirvelraj, Charalampos Panagos, Neda Keyhaninejad, Maxwell Colonna, Pradeep Chopra, Dominic P Byrne, Geert-Jan Boons, Esther van der Knaap, Patrick A Eyers, Arthur S Edison, Zachary A Wood, Natarajan Kannan
A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily. Science signaling 13 (639) (2020)
Safal Shrestha, Dominic P Byrne, John A Harris, Natarajan Kannan, Patrick A Eyers
Cataloguing the dead: breathing new life into pseudokinase research. The FEBS journal 287 (19) (2020)
Dominic P Byrne, Safal Shrestha, Martin Galler, Min Cao, Leonard A Daly, Amy E Campbell, Claire E Eyers, Elizabeth A Veal, Natarajan Kannan, Patrick A Eyers
Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity. Science signaling 13 (639) (2020)
Rahil Taujale, Aarya Venkat, Liang-Chin Huang, Zhongliang Zhou, Wayland Yeung, Khaled M Rasheed, Sheng Li, Arthur S Edison, Kelley W Moremen, Natarajan Kannan
Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases. eLife 9 (2020)
Annie Kwon, Steven Scott, Rahil Taujale, Wayland Yeung, Krys J Kochut, Patrick A Eyers, Natarajan Kannan
Tracing the origin and evolution of pseudokinases across the tree of life. Science signaling 12 (578) (2019)