Amy H Andreotti (Amy Andreotti)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 21

Top Topics

Molecular Dynamics Simulations

Tyrosine Kinase

Chronic Lymphocytic Leukemia

Top Venues

Journal of medicinal chemistry

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. eLife 12 (2024)
Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E Wales, Raji E Joseph, Amy H Andreotti, Jonathan C Strefford, Graham Packham, Matthias G J Baud
Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story. Journal of medicinal chemistry (2024)
David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. eLife 12 (2024)
Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E Wales, Raji E Joseph, Amy H Andreotti, Jonathan C Strefford, Graham Packham, Matthias G J Baud
Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story. Journal of medicinal chemistry 67 (16) (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E Wales, Raji E Joseph, Amy H Andreotti, Jonathan C Strefford, Graham Packham, Matthias G J Baud
Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story. Journal of medicinal chemistry 67 (16) (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. eLife 12 (2024)
David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. eLife 12 (2024)
Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E Wales, Raji E Joseph, Amy H Andreotti, Jonathan C Strefford, Graham Packham, Matthias G J Baud
Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story. Journal of medicinal chemistry 67 (16) (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. eLife 12 (2024)
David Yin-Wei Lin, Amy H Andreotti
Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib. PloS one 18 (8) (2023)
David Yin-Wei Lin, Lauren E Kueffer, Puneet Juneja, Thomas E Wales, John R Engen, Amy H Andreotti
Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. bioRxiv : the preprint server for biology (2023)
Lauren E Kueffer, David Yin-Wei Lin, Neha Amatya, Joseph Serrenho, Raji E Joseph, Adam H Courtney, Amy H Andreotti
Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry (2023)
Raji E Joseph, Thomas E Wales, Sandrine Jayne, Robert Graham Britton, D Bruce Fulton, John R Engen, Martin J S Dyer, Amy H Andreotti
Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. bioRxiv : the preprint server for biology (2023)
Raji E Joseph, Neha Amatya, D Bruce Fulton, John R Engen, Thomas E Wales, Amy H Andreotti
Differential impact of BTK active site inhibitors on the conformational state of full-length BTK. eLife 9 (2020)
Neha Amatya, David Yin-Wei Lin, Amy H Andreotti
Dynamic regulatory features of the protein tyrosine kinases. Biochemical Society transactions 47 (4) (2019)
Sujan Devkota, Raji E Joseph, Scott E Boyken, D Bruce Fulton, Amy H Andreotti
An Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition. Biochemistry 56 (23) (2017)