Volker Dötsch

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 42

Top Venues

eLife

Nature communications

Cell death and differentiation

Cell death & disease

Goethe-Universität Frankfurt

ETH (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Goethe-Universität Frankfurt

Germany

Speaker of the Cluster of Excellence Macromolecular Complexes

Goethe University Frankfurt

Germany

Professor for Biophysical Chemistry (W3)

University of California San Francisco

United States

Adjunct associate professor of Chemistry and Pharmaceutical Chemistry

University of California San Francisco

United States

Adjunct assistant professor of Chemistry and Pharmaceutical Chemistry

University of California, San Francisco

United States

Assistant professor of Chemistry and Pharmaceutical Chemistry

Harvard Medical School

United States

Postdoctoral fellow

Education History

ETH

Switzerland

PHD

Publications

Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors. Life science alliance 7 (8) (2024)
Zoe Köck, Kilian Schnelle, Margherita Persechino, Simon Umbach, Hannes Schihada, Dovile Januliene, Kristian Parey, Steffen Pockes, Peter Kolb, Volker Dötsch, Arne Möller, Daniel Hilger, Frank Bernhard
Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment. Nature communications 15 (1) (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors. Life science alliance 7 (8) (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Amy H Andreotti, Volker Dötsch
Allosteric regulation of kinase activity. eLife 13 (2024)
Zoe Köck, Kilian Schnelle, Margherita Persechino, Simon Umbach, Hannes Schihada, Dovile Januliene, Kristian Parey, Steffen Pockes, Peter Kolb, Volker Dötsch, Arne Möller, Daniel Hilger, Frank Bernhard
Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment. Nature communications 15 (1) (2024)
Zoe Köck, Kilian Schnelle, Margherita Persechino, Simon Umbach, Hannes Schihada, Dovile Januliene, Kristian Parey, Steffen Pockes, Peter Kolb, Volker Dötsch, Arne Möller, Daniel Hilger, Frank Bernhard
Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment. Nature communications 15 (1) (2024)
Alexander Strubel, Philipp Münick, Oliver Hartmann, Apirat Chaikuad, Birgit Dreier, Jonas V Schaefer, Jakob Gebel, Christian Osterburg, Marcel Tuppi, Birgit Schäfer, Viktoria Buck, Mathias Rosenfeldt, Stefan Knapp, Andreas Plückthun, Markus Elmar Diefenbacher, Volker Dötsch
DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell death & disease 14 (10) (2023)
Christian Osterburg, Marco Ferniani, Dario Antonini, Ann-Sophie Frombach, Ludovica D'Auria, Susanne Osterburg, Rebecca Lotz, Frank Loehr, Sebastian Kehrloesser, Huiqing Zhou, Caterina Missero, Volker Dötsch
Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree. Cell death & disease 14 (4) (2023)
Patrick L Purder, Christian Meyners, Wisely Oki Sugiarto, Jürgen Kolos, Frank Loehr, Jakob Gebel, Thomas Nehls, Volker Dötsch, Frederik Lermyte, Felix Hausch
Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues. JACS Au 3 (9) (2023)
Roman Levin, Frank Löhr, Betül Karakoc, Roman Lichtenecker, Volker Dötsch, Frank Bernhard
E. coli "Stablelabel" S30 lysate for optimized cell-free NMR sample preparation. Journal of biomolecular NMR (2023)
Alexis González, Adriana Covarrubias-Pinto, Ramachandra M Bhaskara, Marius Glogger, Santosh Kumar Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E Hoffmann, Bastian Bräuning, Ashwin Balakrishnan, Britta Qualmann, Volker Dötsch, Brenda A Schulman, Michael Manfred Kessels, Christian A Hübner, Mike Heilemann, Gerhard Hummer, Ivan Đikić
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum. Nature (2023)
Rayene Berkane, Hung Ho-Xuan, Marius Glogger, Pablo Sanz-Martinez, Lorene Brunello, Tristan Glaesner, Santosh Kumar Kuncha, Katharina Holzhüter, Sara Cano-Franco, Viviana Buonomo, Paloma Cabrerizo-Poveda, Ashwin Balakrishnan, Georg Tascher, Koraljka Husnjak, Thomas Juretschke, Mohit Misra, Alexis González, Volker Dötsch, Paolo Grumati, Mike Heilemann, Alexandra Stolz
The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways. Nature communications 14 (1) (2023)
Rayene Berkane, Hung Ho-Xuan, Marius Glogger, Pablo Sanz-Martinez, Lorene Brunello, Tristan Glaesner, Santosh Kumar Kuncha, Katharina Holzhüter, Sara Cano-Franco, Viviana Buonomo, Paloma Cabrerizo-Poveda, Ashwin Balakrishnan, Georg Tascher, Koraljka Husnjak, Thomas Juretschke, Mohit Misra, Alexis González, Volker Dötsch, Paolo Grumati, Mike Heilemann, Alexandra Stolz
The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways. Nature communications 14 (1) (2023)
Monika Raab, Yves Matthess, Christopher A Raab, Niklas Gutfreund, Volker Dötsch, Sven Becker, Mourad Sanhaji, Klaus Strebhardt
Correction: A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1. Oncogene (2023)
Christian Osterburg, Volker Dötsch
Structural diversity of p63 and p73 isoforms. Cell death and differentiation 29 (5) (2022)
Niclas Fester, Elisabeth Zielonka, Jakob Goldmann, Ann-Sophie Frombach, Uta Müller-Kuller, Niklas Gutfreund, Kristina Riegel, Jos G A Smits, Enrico Schleiff, Krishnaraj Rajalingam, Huiqing Zhou, Stefan Simm, Volker Dötsch
Enhanced pro-apoptosis gene signature following the activation of TAp63α in oocytes upon γ irradiation. Cell death & disease 13 (3) (2022)
Alexander Strubel, Philipp Münick, Apirat Chaikuad, Birgit Dreier, Jonas Schaefer, Jakob Gebel, Christian Osterburg, Marcel Tuppi, Birgit Schäfer, Stefan Knapp, Andreas Plückthun, Volker Dötsch
Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell death and differentiation (2022)
Nicole Wesch, Frank Loehr, Natalia Rogova, Volker Dötsch, Vladimir V Rogov
A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1. International journal of molecular sciences 22 (14) (2021)
Eleonora Candi, Gerry Melino, Attila Tóth, Volker Dötsch
Mechanisms of quality control differ in male and female germ cells. Cell death and differentiation 28 (7) (2021)
Anna Maria Lena, Valerio Rossi, Susanne Osterburg, Artem Smirnov, Christian Osterburg, Marcel Tuppi, Angela Cappello, Ivano Amelio, Volker Dötsch, Massimo De Felici, Francesca Gioia Klinger, Margherita Annicchiarico-Petruzzelli, Herbert Valensise, Gerry Melino, Eleonora Candi
The p63 C-terminus is essential for murine oocyte integrity. Nature communications 12 (1) (2021)
Monika Raab, Yves Matthess, Christopher A Raab, Niklas Gutfreund, Volker Dötsch, Sven Becker, Mourad Sanhaji, Klaus Strebhardt
A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1. Oncogene (2021)
Anthea Di Rita, Daniela F Angelini, Teresa Maiorino, Valerio Caputo, Raffaella Cascella, Mukesh Kumar, Matteo Tiberti, Matteo Lambrughi, Nicole Wesch, Frank Löhr, Volker Dötsch, Marianna Carinci, Pasquale D Acunzo, Valerio Chiurchiù, Elena Papaleo, Vladimir V Rogov, Emiliano Giardina, Luca Battistini, Flavie Strappazzon
Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy. Cell death and differentiation 28 (8) (2021)
Christian Osterburg, Susanne Osterburg, Huiqing Zhou, Caterina Missero, Volker Dötsch
Isoform-Specific Roles of Mutant p63 in Human Diseases. Cancers 13 (3) (2021)
Anna Lopata, Andreas Kniss, Frank Loehr, Vladimir V Rogov, Volker Dötsch
Ubiquitination in the ERAD Process. International journal of molecular sciences 21 (15) (2020)
Jakob Gebel, Marcel Tuppi, Nicole Sänger, Björn Schumacher, Volker Dötsch
DNA Damaged Induced Cell Death in Oocytes. Molecules (Basel, Switzerland) 25 (23) (2020)
Jakob Gebel, Marcel Tuppi, Apirat Chaikuad, Katharina Hötte, Martin Schröder, Laura Schulz, Frank Löhr, Niklas Gutfreund, Franziska Finke, Erik Henrich, Julija Mezhyrova, Ralf Lehnert, Francesco Pampaloni, Gerhard Hummer, Ernst H K Stelzer, Stefan Knapp, Volker Dötsch
p63 uses a switch-like mechanism to set the threshold for induction of apoptosis. Nature chemical biology 16 (10) (2020)
Susanne Pitzius, Christian Osterburg, Jakob Gebel, Georg Tascher, Birgit Schäfer, Huiqing Zhou, Christian Münch, Volker Dötsch
TA*p63 and GTAp63 achieve tighter transcriptional regulation in quality control by converting an inhibitory element into an additional transactivation domain. Cell death & disease 10 (10) (2019)
Søs Grønbæk Holdgaard, Valentina Cianfanelli, Emanuela Pupo, Matteo Lambrughi, Michal Lubas, Julie C Nielsen, Susana Eibes, Emiliano Maiani, Lea M Harder, Nicole Wesch, Mads Møller Foged, Kenji Maeda, Francesca Nazio, Laura Rodriguez de la Ballina, Volker Dötsch, Andreas Brech, Lisa B Frankel, Marja Jäättelä, Franco Locatelli, Marin Barisic, Jens S Andersen, Simon Bekker-Jensen, Anders Henrik Lund, Vladimir V Rogov, Elena Papaleo, Letizia Lanzetti, Daniela De Zio, Francesco Cecconi
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nature communications 10 (1) (2019)
Kriti D Khandelwal, Marie-José H van den Boogaard, Sarah L Mehrem, Jakob Gebel, Christina R Fagerberg, Ellen van Beusekom, Ellen van Binsbergen, Ozan Topaloglu, Marloes Steehouwer, Christian Gilissen, Nina Ishorst, Iris A L M van Rooij, Nel Roeleveld, Kaare Christensen, Joseph Schoenaers, Stefaan Bergé, Jeffrey C Murray, Greet Hens, Koenraad Devriendt, Kerstin U Ludwig, Elisabeth Mangold, Alexander Hoischen, Huiqing Zhou, Volker Dötsch, Carine E L Carels, Hans van Bokhoven
Deletions and loss-of-function variants in TP63 associated with orofacial clefting. European journal of human genetics : EJHG 27 (7) (2019)
Tanja Frank, Marcel Tuppi, Manuela Hugle, Volker Dötsch, Sjoerd J L van Wijk, Simone Fulda
Cell cycle arrest in mitosis promotes interferon-induced necroptosis. Cell death and differentiation 26 (10) (2019)
Sebastian Kehrloesser, Marcel Tuppi, Volker Dötsch
CHK2 sets the stage for CK1 in oocyte quality control. Cell death and differentiation 25 (6) (2019)
Marcel Tuppi, Sebastian Kehrloesser, Daniel W Coutandin, Valerio Rossi, Laura M Luh, Alexander Strubel, Katharina Hötte, Meike Hoffmeister, Birgit Schäfer, Tiago De Oliveira, Florian Greten, Ernst H K Stelzer, Stefan Knapp, Massimo De Felici, Christian Behrends, Francesca Gioia Klinger, Volker Dötsch
Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63. Nature structural & molecular biology 25 (3) (2018)
Susanne Müller, Suzanne Ackloo, Cheryl H Arrowsmith, Marcus Bauser, Jeremy L Baryza, Julian Blagg, Jark Böttcher, Chas Bountra, Peter J Brown, Mark E Bunnage, Adrian J Carter, David Damerell, Volker Dötsch, David H Drewry, Aled M Edwards, James Edwards, Jonathan M Elkins, Christian Fischer, Stephen V Frye, Andreas Gollner, Charles E Grimshaw, Adriaan IJzerman, Thomas Hanke, Ingo V Hartung, Steve Hitchcock, Trevor Howe, Terry V Hughes, Stefan Laufer, Volkhart Mj Li, Spiros Liras, Brian D Marsden, Hisanori Matsui, John Mathias, Ronan C O'Hagan, Dafydd R Owen, Vineet Pande, Daniel Rauh, Saul H Rosenberg, Bryan L Roth, Natalie S Schneider, Cora Scholten, Kumar Singh Saikatendu, Anton Simeonov, Masayuki Takizawa, Chris Tse, Paul R Thompson, Daniel K Treiber, Amélia Yi Viana, Carrow I Wells, Timothy M Willson, William J Zuercher, Stefan Knapp, Anke Mueller-Fahrnow
Donated chemical probes for open science. eLife 7 (2018)
Christoph Bock, Frank Löhr, Franz Tumulka, Katrin Reichel, Julia Würz, Gerhard Hummer, Lars Schäfer, Robert Tampé, Benesh Joseph, Frank Bernhard, Volker Dötsch, Rupert Abele
Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL. Scientific reports 8 (1) (2018)
Jakob Gebel, Marcel Tuppi, Katharina Krauskopf, Daniel Coutandin, Susanne Pitzius, Sebastian Kehrloesser, Christian Osterburg, Volker Dötsch
Control mechanisms in germ cells mediated by p53 family proteins. Journal of cell science (2017)
Christopher Hein, Frank Löhr, Daniel Schwarz, Volker Dötsch
Acceleration of protein backbone NMR assignment by combinatorial labeling: Application to a small molecule binding study. Biopolymers 107 (5) (2017)
Erik Henrich, Oliver Peetz, Christopher Hein, Aisha Laguerre, Beate Hoffmann, Jan Hoffmann, Volker Dötsch, Frank Bernhard, Nina Morgner
Analyzing native membrane protein assembly in nanodiscs by combined non-covalent mass spectrometry and synthetic biology. eLife 6 (2017)
Daniel Coutandin, Christian Osterburg, Ratnesh Kumar Srivastav, Manuela Sumyk, Sebastian Kehrloesser, Jakob Gebel, Marcel Tuppi, Jens Hannewald, Birgit Schäfer, Eidarus Salah, Sebastian Mathea, Uta Müller-Kuller, James Doutch, Manuel Grez, Stefan Knapp, Volker Dötsch
Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level. eLife 5 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Volker Dötsch