Ann-Sofie Jemth

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 9

Top Venues

The Journal of biological chemistry

Biochemistry

Nature cancer

Human mutation

Karolinska Institutet

Uppsala University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Karolinska Institutet

Sweden

Researcher and Team leader :: Department of Oncology and Pathology

Karolinska Institutet

Sweden

Researcher and Team leader :: Department of Medical Biochemistry and Biophysics

Stockholms Universitet

Sweden

Research Associate :: Department of Genetics, Microbiology and Toxicology

MRC Laboratory of Molecular Biology

United Kingdom

Research Associate :: PNAC

Uppsala Universitet

Sweden

PhD position :: Department of Biochemistry

Education History

Uppsala University

Sweden

PHD :: Department of Biochemistry

Uppsala University

Sweden

MSC

Publications

Emma R Scaletti, Judith E Unterlass, Ingrid Almlöf, Tobias Koolmeister, Karl S Vallin, Despina Kapsitidou, Viktoriia Tsuber, Thomas Helleday, Pål Stenmark, Ann-Sofie Jemth
Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis. The FEBS journal (2024)
Alanna C Green, Petra Marttila, Nicole Kiweler, Christina Chalkiadaki, Elisée Wiita, Victoria Cookson, Antoine Lesur, Kim Eiden, François Bernardin, Karl S A Vallin, Sanjay Borhade, Maeve Long, Elahe Kamali Ghahe, Julio J Jiménez-Alonso, Ann-Sofie Jemth, Olga Loseva, Oliver Mortusewicz, Marianne Meyers, Elodie Viry, Annika I Johansson, Ondrej Hodek, Evert Homan, Nadilly Bonagas, Louise Ramos, Lars Sandberg, Morten Frödin, Etienne Moussay, Ana Slipicevic, Elisabeth Letellier, Jérôme Paggetti, Claus Storgaard Sørensen, Thomas Helleday, Martin Henriksson, Johannes Meiser
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells. Nature metabolism (2023)
Maurice Michel, Carlos Benítez-Buelga, Patricia A Calvo, Bishoy M F Hanna, Oliver Mortusewicz, Geoffrey Masuyer, Jonathan R Davies, Olov Wallner, Kumar Sanjiv, Julian J Albers, Sergio Castañeda-Zegarra, Ann-Sofie Jemth, Torkild Visnes, Ana Sastre-Perona, Akhilesh N Danda, Evert J Homan, Karthick Marimuthu, Zhao Zhenjun, Celestine N Chi, Antonio Sarno, Elisée Wiita, Catharina von Nicolai, Anna J Komor, Varshni Rajagopal, Sarah Müller, Emily C Hank, Marek Varga, Emma R Scaletti, Monica Pandey, Stella Karsten, Hanne Haslene-Hox, Simon Loevenich, Petra Marttila, Azita Rasti, Kirill Mamonov, Florian Ortis, Fritz Schömberg, Olga Loseva, Josephine Stewart, Nicholas D'Arcy-Evans, Tobias Koolmeister, Martin Henriksson, Dana Michel, Ana de Ory, Lucia Acero, Oriol Calvete, Martin Scobie, Christian Hertweck, Ivan Vilotijevic, Christina Kalderén, Ana Osorio, Rosario Perona, Alexandra Stolz, Pål Stenmark, Ulrika Warpman Berglund, Miguel de Vega, Thomas Helleday
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science (New York, N.Y.) 376 (6600) (2022)
Nadilly Bonagas, Nina M S Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Elisée Wiita, Sanjay Borhade, Alanna C Green, Karl S A Vallin, Antonio Sarno, Richard Svensson, Camilla Göktürk, Therese Pham, Ann-Sofie Jemth, Olga Loseva, Victoria Cookson, Nicole Kiweler, Lars Sandberg, Azita Rasti, Judith E Unterlass, Martin Haraldsson, Yasmin Andersson, Emma R Scaletti, Christoffer Bengtsson, Cynthia B J Paulin, Kumar Sanjiv, Eldar Abdurakhmanov, Linda Pudelko, Ben Kunz, Matthieu Desroses, Petar Iliev, Katarina Färnegårdh, Andreas Krämer, Neeraj Garg, Maurice Michel, Sara Häggblad, Malin Jarvius, Christina Kalderén, Amanda Bögedahl Jensen, Ingrid Almlöf, Stella Karsten, Si Min Zhang, Maria Häggblad, Anders Eriksson, Jianping Liu, Björn Glinghammar, Natalia Nekhotiaeva, Fredrik Klingegård, Tobias Koolmeister, Ulf Martens, Sabin Llona-Minguez, Ruth Moulson, Helena Nordström, Vendela Parrow, Leif Dahllund, Birger Sjöberg, Irene L Vargas, Duy Duc Vo, Johan Wannberg, Stefan Knapp, Hans E Krokan, Per I Arvidsson, Martin Scobie, Johannes Meiser, Pål Stenmark, Ulrika Warpman Berglund, Evert J Homan, Thomas Helleday
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress. Nature cancer 3 (2) (2022)
Emma Rose Scaletti, Karl S Vallin, Lars Bräutigam, Antonio Sarno, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark, Ann-Sofie Jemth
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool. The Journal of biological chemistry 295 (15) (2020)
Jana Škerlová, Judith Unterlass, Mona Göttmann, Petra Marttila, Evert Homan, Thomas Helleday, Ann-Sofie Jemth, Pål Stenmark
Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target. The Journal of biological chemistry 295 (33) (2020)
Ann-Sofie Jemth, Emma Scaletti, Megan Carter, Thomas Helleday, Pål Stenmark
Crystal Structure and Substrate Specificity of the 8-oxo-dGTP Hydrolase NUDT1 from Arabidopsis thaliana. Biochemistry 58 (7) (2019)
Mohit Narwal, Ann-Sofie Jemth, Robert Gustafsson, Ingrid Almlöf, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark
Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry 57 (5) (2018)
Pilar Mur, Ann-Sofie Jemth, Luka Bevc, Nuno Amaral, Matilde Navarro, Rafael Valdés-Mas, Tirso Pons, Gemma Aiza, Miguel Urioste, Alfonso Valencia, Conxi Lazaro Garcia, Victor Moreno, Xose S Puente, Pål Stenmark, Ulrika Warpman-Berglund, Gabriel Capellá Munar, Thomas Helleday, Laura Valle
Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis. Human mutation 39 (9) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ann-Sofie Jemth