Annette Künkele

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 30

Top Topics

Minimally Invasive

Top Venues

International journal of molecular sciences

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells. Blood 143 (25) (2024)
Ngoc Thien Thu Nguyen, Rasmus Müller, Daria Briukhovetska, Justus Weber, Judith Feucht, Annette Künkele, Michael Hudecek, Sebastian Kobold
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 16 (14) (2024)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells. Blood 143 (25) (2024)
Ngoc Thien Thu Nguyen, Rasmus Müller, Daria Briukhovetska, Justus Weber, Judith Feucht, Annette Künkele, Michael Hudecek, Sebastian Kobold
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 16 (14) (2024)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. Blood (2024)
Ngoc Thien Thu Nguyen, Rasmus Müller, Daria Briukhovetska, Justus Weber, Judith Feucht, Annette Künkele, Michael Hudecek, Sebastian Kobold
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 16 (14) (2024)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. Blood (2024)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. Blood (2024)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. bioRxiv : the preprint server for biology (2023)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. bioRxiv : the preprint server for biology (2023)
Francesca Del Bufalo, Marco Becilli, Chiara Rosignoli, Biagio De Angelis, Mattia Algeri, Linda Hanssens, Monica Gunetti, Stefano Iacovelli, Giuseppina Li Pira, Elia Girolami, Giovanna Leone, Stefania Lazzaro, Valentina Bertaina, Matilde Sinibaldi, Stefano Di Cecca, Laura Iaffaldano, Annette Künkele, Emilia Boccieri, Giada Del Baldo, Daria Pagliara, Pietro Merli, Roberto Carta, Concetta Quintarelli, Franco Locatelli
Allogeneic, donor-derived, second-generation, CD19-CAR-T cell for the treatment of pediatric relapsed/refractory BCP-ALL. Blood (2023)
Steffen Fuchs, Clara Danßmann, Filippos Klironomos, Annika Winkler, Jörg Fallmann, Louisa-Marie Kruetzfeldt, Annabell Krienelke-Szymansky, Julian Naderi, Stephan H Bernhart, Laura Grunewald, Konstantin Helmsauer, Elias Rodriguez-Fos, Marieluise Kirchner, Philipp Mertins, Kathy Astrahantseff, Christin Suenkel, Joern Toedling, Fabienne Meggetto, Marc Remke, Peter F Stadler, Patrick Hundsdoerfer, Hedwig E Deubzer, Annette Künkele, Peter Lang, Jörg Fuchs, Anton G Henssen, Angelika Eggert, Nikolaus Rajewsky, Falk Hertwig, Johannes Hubertus Schulte
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN. Nature communications 14 (1) (2023)
Peter Bader, Claudia Rossig, Martin Hutter, Francis Ayuketang Ayuk, Claudia D Baldus, Veit L Bücklein, Halvard Bonig, Gunnar Cario, Hermann Einsele, Udo Holtick, Christian Koenecke, Shahrzad Bakhtiar, Annette Künkele, Richard P Meisel, Fabian Mueller, Ingo Müller, Olaf Penack, Eva Rettinger, Martin G Sauer, Paul-Gerhardt Schlegel, Jan Soerensen, Arend von Stackelberg, Brigitte Strahm, Tobias Feuchtinger, Julia Hauer, Andrea Jarisch
CD19-CAR-T cells are an effective therapy of post-transplant relapse in B- ALL patients: Real-World Data from Germany. Blood advances (2023)
Jonas Kath, Clemens Franke, Vanessa Drosdek, Weijie Du, Viktor Glaser, Carla Fuster-García, Maik Stein, Tatiana Zittel, Sarah Schulenberg, Caroline E Porter, Lena Andersch, Annette Künkele, Joshua Alcaniz, Jens Hoffmann, Hinrich Abken, Mohamed Abou-El-Enein, Axel Pruß, Masataka Suzuki, Toni Cathomen, Renata Stripecke, Hans-Dieter Volk, Petra Reinke, Michael Schmueck-Henneresse, Dimitrios Laurin Wagner
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells. bioRxiv : the preprint server for biology (2023)
Karin Teppert, Xueting Wang, Kathleen Anders, César Evaristo, Dominik Lock, Annette Künkele
Joining Forces for Cancer Treatment: From "TCR versus CAR" to "TCR and CAR". International journal of molecular sciences 23 (23) (2022)
Marco Lodrini, Jasmin Wünschel, Theresa M Thole-Kliesch, Maddalena Grimaldi, Annika Sprüssel, Rasmus B Linke, Jan F Hollander, Daniela Tiburtius, Annette Künkele, Johannes Hubertus Schulte, Erwin Lankes, Thomas Elgeti, Patrick Hundsdörfer, Kathy Astrahantseff, Thorsten Simon, Angelika Eggert, Hedwig E Deubzer
Circulating Cell-Free DNA Assessment in Biofluids from Children with Neuroblastoma Demonstrates Feasibility and Potential for Minimally Invasive Molecular Diagnostics. Cancers 14 (9) (2022)
Karin Teppert, Xueting Wang, Kathleen Anders, César Evaristo, Dominik Lock, Annette Künkele
Joining Forces for Cancer Treatment: From "TCR versus CAR" to "TCR and CAR". International journal of molecular sciences 23 (23) (2022)
Karin Teppert, Xueting Wang, Kathleen Anders, César Evaristo, Dominik Lock, Annette Künkele
Joining Forces for Cancer Treatment: From "TCR versus CAR" to "TCR and CAR". International journal of molecular sciences 23 (23) (2022)
Marco Lodrini, Josefine Graef, Theresa M Thole-Kliesch, Kathy Astrahantseff, Annika Sprüssel, Maddalena Grimaldi, Constantin Peitz, Rasmus B Linke, Jan F Hollander, Erwin Lankes, Annette Künkele, Lena Oevermann, Georg Schwabe, Jörg Fuchs, Annabell Krienelke-Szymansky, Johannes Hubertus Schulte, Patrick Hundsdörfer, Cornelia Eckert, Holger Amthauer, Angelika Eggert, Hedwig E Deubzer
Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (9) (2022)
Karin Teppert, Xueting Wang, Kathleen Anders, César Evaristo, Dominik Lock, Annette Künkele
Joining Forces for Cancer Treatment: From "TCR versus CAR" to "TCR and CAR". International journal of molecular sciences 23 (23) (2022)
Karin Teppert, Xueting Wang, Kathleen Anders, César Evaristo, Dominik Lock, Annette Künkele
Joining Forces for Cancer Treatment: From "TCR versus CAR" to "TCR and CAR". International journal of molecular sciences 23 (23) (2022)
Annabell Krienelke-Szymansky, Louisa-Marie Kruetzfeldt, Lukas C Heukamp, Falk Hertwig, Jessica Theissen, Hedwig E Deubzer, Eva-Maria Willing, Roopika Menon, Steffen Fuchs, Theresa Thole, Stefanie Schulte, Karin Schmelz, Annette Künkele, Peter Lang, Jörg Fuchs, Angelika Eggert, Cornelia Eckert, Matthias Fischer, Anton G Henssen, Elias Rodriguez-Fos, Johannes H Schulte
Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing. Journal of personalized medicine 11 (8) (2021)
Anna M Mc Laughlin, Nahum Puebla-Osorio, Robin Michelet, Michael R Green, Annette Künkele, Wilhelm Huisinga, Paolo Strati, Beth Chasen, Sattva S Neelapu, Cassian Yee, Charlotte Kloft
Early Survival Prediction Framework in CD19-Specific CAR-T Cell Immunotherapy Using a Quantitative Systems Pharmacology Model. Cancers 13 (11) (2021)
Ornela Sulejmani, Laura Grunewald, Lena Andersch, Silke Schwiebert, Anika Klaus, Annika Winkler, Kathy Astrahantseff, Angelika Eggert, Anton G Henssen, Johannes Hubertus Schulte, Kathleen Anders, Annette Künkele
Inhibiting Lysine Demethylase 1A Improves L1CAM-Specific CAR T Cell Therapy by Unleashing Antigen-Independent Killing via the FAS-FASL Axis. Cancers 13 (21) (2021)
Nicholas A Vitanza, Adam J Johnson, Ashley L Wilson, Christopher Brown, Jason K Yokoyama, Annette Künkele, Cindy A Chang, Stephanie Rawlings-Rhea, Wenjun Huang, Kristy Seidel, Catherine M Albert, Navin R Pinto, Juliane Gust, Laura S Finn, Jeffrey G Ojemann, Jason Wright, Rimas J Orentas, Michael Baldwin, Rebecca A Gardner, Michael C Jensen, Julie R Park
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis. Nature medicine 27 (9) (2021)
Adam J Johnson, Jia Wei, James M Rosser, Annette Künkele, Cindy A Chang, Aquene N Reid, Michael C Jensen
Rationally Designed Transgene-Encoded Cell-Surface Polypeptide Tag for Multiplexed Programming of CAR T-cell Synthetic Outputs. Cancer immunology research 9 (9) (2021)
Ana Textor, Laura Grunewald, Kathleen Anders, Anika Klaus, Silke Schwiebert, Annika Winkler, Maria Stecklum, Jana Rolff, Anton G Henssen, Uta E Höpken, Angelika Eggert, Johannes H Schulte, Michael C Jensen, Thomas Blankenstein, Annette Künkele
CD28 Co-Stimulus Achieves Superior CAR T Cell Effector Function against Solid Tumors Than 4-1BB Co-Stimulus. Cancers 13 (5) (2021)
Karin Toews, Laura Grunewald, Silke Schwiebert, Anika Klaus, Annika Winkler, Solin Ali, Felix Zirngibl, Kathy Astrahantseff, Dimitrios L Wagner, Anton G Henssen, Hedwig E Deubzer, Johannes H Schulte, Sebastian Ochsenreither, Angelika Eggert, Annette Künkele
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells. Molecular carcinogenesis 59 (7) (2020)
Felix Zirngibl, Carina Flemmig, Peter Lang, Annette Künkele, Angelika Eggert, Johannes H Schulte, Hedwig E Deubzer
Sinusoidal Obstruction Syndrome Following Myeloablative Therapy and Tranexamic Acid Treatment for Hemorrhage in Two Patients with Neuroblastoma. Children (Basel, Switzerland) 7 (11) (2020)
Lena Andersch, Josefine Radke, Anika Klaus, Silke Schwiebert, Annika Winkler, Elisa Schumann, Laura Grunewald, Felix Zirngibl, Carina Flemmig, Michael C Jensen, Claudia Rossig, Antonia Joussen, Anton Henssen, Angelika Eggert, Johannes H Schulte, Annette Künkele
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing. BMC cancer 19 (1) (2019)