Sebastian Kobold

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 62

Top Topics

Chronic Lymphocytic Leukemia

Finite Element Analysis

Top Venues

Nature communications

Nature medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Ngoc Thien Thu Nguyen, Rasmus Müller, Daria Briukhovetska, Justus Weber, Judith Feucht, Annette Künkele, Michael Hudecek, Sebastian Kobold
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 16 (14) (2024)
Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V van Blokland, Roy Oelen, Hilde E Groot, Jan-Walter Benjamins, Sophia Brambs, Rainer W J Kaiser, Adrian Gottschlich, Gordon Victor Hoffmann, Luke Eivers, Alejandro Martinez Navarro, Nils Bruns, Susanne Stiller, Sezer Akgöl, Keyang Yue, Vivien Polewka, Raphael Escaig, Markus Joppich, Aleksandar Janjic, Oliver Popp, Sebastian Kobold, Tobias Petzold, Ralf Zimmer, Wolfgang Enard, Kathrin Saar, Philipp Mertins, Norbert Hübner, Pim van der Harst, Lude H Franke, Monique G P van der Wijst, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nature medicine (2024)
Ngoc Thien Thu Nguyen, Rasmus Müller, Daria Briukhovetska, Justus Weber, Judith Feucht, Annette Künkele, Michael Hudecek, Sebastian Kobold
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 16 (14) (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V van Blokland, Roy Oelen, Hilde E Groot, Jan-Walter Benjamins, Sophia Brambs, Rainer W J Kaiser, Adrian Gottschlich, Gordon Victor Hoffmann, Luke Eivers, Alejandro Martinez Navarro, Nils Bruns, Susanne Stiller, Sezer Akgöl, Keyang Yue, Vivien Polewka, Raphael Escaig, Markus Joppich, Aleksandar Janjic, Oliver Popp, Sebastian Kobold, Tobias Petzold, Ralf Zimmer, Wolfgang Enard, Kathrin Saar, Philipp Mertins, Norbert Hübner, Pim van der Harst, Lude H Franke, Monique G P van der Wijst, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nature medicine 30 (6) (2024)
Marcel Philipp Trefny, Sebastian Kobold
CAR T cells for solid tumors - developments to watch in 2023. Expert opinion on biological therapy (2024)
Ngoc Thien Thu Nguyen, Rasmus Müller, Daria Briukhovetska, Justus Weber, Judith Feucht, Annette Künkele, Michael Hudecek, Sebastian Kobold
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 16 (14) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature (2024)
Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V van Blokland, Roy Oelen, Hilde E Groot, Jan-Walter Benjamins, Sophia Brambs, Rainer W J Kaiser, Adrian Gottschlich, Gordon Victor Hoffmann, Luke Eivers, Alejandro Martinez Navarro, Nils Bruns, Susanne Stiller, Sezer Akgöl, Keyang Yue, Vivien Polewka, Raphael Escaig, Markus Joppich, Aleksandar Janjic, Oliver Popp, Sebastian Kobold, Tobias Petzold, Ralf Zimmer, Wolfgang Enard, Kathrin Saar, Philipp Mertins, Norbert Hübner, Pim van der Harst, Lude H Franke, Monique G P van der Wijst, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nature medicine 30 (6) (2024)
Sebastian Kobold
Giving T-cell bispecifics a helping hand. Blood 143 (21) (2024)
Christina Angeliki Tsiverioti, Adrian Gottschlich, Marcel Philipp Trefny, Sebastian Theurich, Hans-Johachim Anders, Matthias Kroiss, Sebastian Kobold
Beyond CAR T cells: exploring alternative cell sources for CAR-like cellular therapies. Biological chemistry 405 (7-8) (2024)
Marcel Philipp Trefny, Sebastian Kobold
CAR T cells for solid tumors - developments to watch in 2023. Expert opinion on biological therapy 24 (4) (2024)
Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V van Blokland, Roy Oelen, Hilde E Groot, Jan-Walter Benjamins, Sophia Brambs, Rainer W J Kaiser, Adrian Gottschlich, Gordon Victor Hoffmann, Luke Eivers, Alejandro Martinez Navarro, Nils Bruns, Susanne Stiller, Sezer Akgöl, Keyang Yue, Vivien Polewka, Raphael Escaig, Markus Joppich, Aleksandar Janjic, Oliver Popp, Sebastian Kobold, Tobias Petzold, Ralf Zimmer, Wolfgang Enard, Kathrin Saar, Philipp Mertins, Norbert Hübner, Pim van der Harst, Lude H Franke, Monique G P van der Wijst, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nature medicine 30 (6) (2024)
Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V van Blokland, Roy Oelen, Hilde E Groot, Jan-Walter Benjamins, Sophia Brambs, Rainer W J Kaiser, Adrian Gottschlich, Gordon Victor Hoffmann, Luke Eivers, Alejandro Martinez Navarro, Nils Bruns, Susanne Stiller, Sezer Akgöl, Keyang Yue, Vivien Polewka, Raphael Escaig, Markus Joppich, Aleksandar Janjic, Oliver Popp, Sebastian Kobold, Tobias Petzold, Ralf Zimmer, Wolfgang Enard, Kathrin Saar, Philipp Mertins, Norbert Hübner, Pim van der Harst, Lude H Franke, Monique G P van der Wijst, Steffen Massberg, Matthias Heinig, Leo Nicolai, Konstantin Stark
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nature medicine (2024)
Christina Angeliki Tsiverioti, Adrian Gottschlich, Sebastian Theurich, Hans-Johachim Anders, Matthias Kroiss, Sebastian Kobold, Marcel Philipp Trefny
Beyond CAR T cells: exploring alternative cell sources for CAR-like cellular therapies. Biological chemistry (2024)
Marcel Philipp Trefny, Sebastian Kobold
CAR T cells for solid tumors - developments to watch in 2023. Expert opinion on biological therapy 24 (4) (2024)
Christina Angeliki Tsiverioti, Adrian Gottschlich, Marcel Philipp Trefny, Sebastian Theurich, Hans-Johachim Anders, Matthias Kroiss, Sebastian Kobold
Beyond CAR T cells: exploring alternative cell sources for CAR-like cellular therapies. Biological chemistry (2024)
Florian Märkl, Christoph Schultheiß, Murtaza Ali, Shih-Shih Chen, Marina Zintchenko, Lukas Egli, Juliane Mietz, Obinna Chijioke, Lisa Paschold, Sebastijan Spajic, Anne Holtermann, Janina Dörr, Sophia Stock, Andreas Zingg, Heinz Laubli, Ignazio Piseddu, David Anz, Marcus Dühren-von Minden, Tianjiao Zhang, Thomas Nerreter, Michael Hudecek, Susana Minguet, Nicholas Chiorazzi, Sebastian Kobold, Mascha Binder
Mutation-specific CAR T cells as precision therapy for IGLV3-21 R110 expressing high-risk chronic lymphocytic leukemia. Nature communications 15 (1) (2024)
Marcel Philipp Trefny, Sebastian Kobold
CAR T cells for solid tumors - developments to watch in 2023. Expert opinion on biological therapy 24 (4) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Christina Angeliki Tsiverioti, Adrian Gottschlich, Marcel Philipp Trefny, Sebastian Theurich, Hans-Johachim Anders, Matthias Kroiss, Sebastian Kobold
Beyond CAR T cells: exploring alternative cell sources for CAR-like cellular therapies. Biological chemistry 405 (7-8) (2024)
Marine Fidelle, Conrad Rauber, Carolina Alves Costa Silva, Ai-Ling Tian, Imran Lahmar, Anne-Laure Mallard de La Varende, Liwei Zhao, Cassandra Thelemaque, Isabelle Lebhar, Meriem Messaoudene, Eugenie Pizzato, Roxanne Birebent, Maxime Descartes Mbogning Fonkou, Silvia Zoppi, Anna Reni, Cécile Dalban, Marion Leduc, Gladys Ferrere, Sylvère Durand, Pierre Ly, Aymeric Silvin, Kevin Mulder, Charles-Antoine Dutertre, Florent Ginhoux, Satoru Yonekura, Maria Paula Roberti, Maryam Tidjani Alou, Safae Terrisse, Jianzhou Chen, Oliver Kepp, Angela Schippers, Norbert Wagner, Javier Suarez-Gosalvez, Sebastian Kobold, Jean-Eudes Fahrner, Corentin Richard, Jacques Bosq, Leonardo Lordello, Giacomo Vitali, Nathalie Galleron, Benoit Quinquis, Emmanuelle Le Chatelier, Lucas Blanchard, Jean-Philippe Girard, Anne Jarry, Nadine Gervois-Segain, Emmanuelle Godefroy, Nathalie Labarrière, Ronald Koschny, Romain Daillère, Benjamin Besse, Caroline Truntzer, François Ghiringhelli, Nicolas Coatnoan, Vanessa Mhanna, David Klatzmann, Damien Drubay, Laurence Albiges, Andrew Maltez Thomas, Nicola Segata, François-Xavier Danlos, Aurélien Marabelle, Bertrand Routy, Lisa Derosa, Guido Kroemer, Laurence Zitvogel
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers. Science (New York, N.Y.) 380 (6649) (2023)
Florian Märkl, Mohamed-Reda Benmebarek, Julius Keyl, Bruno L Cadilha, Martina Geiger, Clara Karches, Hannah Obeck, Melanie Schwerdtfeger, Stefanos Michaelides, Daria Briukhovetska, Sophia Stock, Jakob Jobst, Philipp Jie Müller, Lina Majed, Matthias Seifert, Anna-Kristina Klüver, Theo Lorenzini, Ruth Grünmeier, Moritz Thomas, Adrian Gottschlich, Richard Klaus, Carsten Marr, Michael von Bergwelt-Baildon, Simon Rothenfusser, Mitchell P Levesque, Markus Vincent Heppt, Stefan Endres, Christiane Neumann, Sebastian Kobold
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma. Journal for immunotherapy of cancer 11 (5) (2023)
Hao Wu, Xiufeng Zhao, Sophia M Hochrein, Miriam Eckstein, Gabriela F Gubert, Konrad Knöpper, Ana Maria Mansilla, Arman Öner, Remi Doucet-Ladevèze, Werner Schmitz, Bart Ghesquiere, Sebastian Theurich, Jan Dudek, Georg Gasteiger, Alma Zernecke, Sebastian Kobold, Wolfgang Kastenmüller, Martin Vaeth
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming. Nature communications 14 (1) (2023)
David Andreu-Sanz, Sebastian Kobold
Role and Potential of Different T Helper Cell Subsets in Adoptive Cell Therapy. Cancers 15 (6) (2023)
Klaus F Wagenbauer, Nhi Pham, Adrian Gottschlich, Benjamin Kick, Viktorija Kozina, Christopher Frank, Daniela Trninic, Pierre Stömmer, Ruth Grünmeier, Emanuele Carlini, Christina Angeliki Tsiverioti, Sebastian Kobold, Jonas J Funke, Hendrik Dietz
Programmable multispecific DNA-origami-based T-cell engagers. Nature nanotechnology (2023)
Florian Märkl, Mohamed-Reda Benmebarek, Julius Keyl, Bruno L Cadilha, Martina Geiger, Clara Karches, Hannah Obeck, Melanie Schwerdtfeger, Stefanos Michaelides, Daria Briukhovetska, Sophia Stock, Jakob Jobst, Philipp Jie Müller, Lina Majed, Matthias Seifert, Anna-Kristina Klüver, Theo Lorenzini, Ruth Grünmeier, Moritz Thomas, Adrian Gottschlich, Richard Klaus, Carsten Marr, Michael von Bergwelt-Baildon, Simon Rothenfusser, Mitchell P Levesque, Markus Vincent Heppt, Stefan Endres, Christiane Neumann, Sebastian Kobold
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma. Journal for immunotherapy of cancer 11 (5) (2023)
Adrian Gottschlich, Moritz Thomas, Ruth Grünmeier, Stefanie Lesch, Lisa Rohrbacher, Veronika Igl, Daria Briukhovetska, Mohamed-Reda Benmebarek, Binje Vick, Sertac Dede, Katharina Müller, Tao Xu, Dario Dhoqina, Florian Märkl, Sophie Robinson, Andrea Sendelhofert, Heiko Schulz, Öykü Umut, Vladyslav Kavaka, Christina Angeliki Tsiverioti, Emanuele Carlini, Sayantan Nandi, Thaddäus Strzalkowski, Theo Lorenzini, Sophia Stock, Philipp Jie Müller, Janina Dörr, Matthias Seifert, Bruno Loureiro Cadilha, Ruben Brabenec, Natalie Röder, Felicitas Rataj, Manuel Nüesch, Franziska Modemann, Jasmin Wellbrock, Walter Fiedler, Christian Kellner, Eduardo Beltrán, Tobias Herold, Dominik Paquet, Irmela Jeremias, Louisa von Baumgarten, Stefan Endres, Marion Subklewe, Carsten Marr, Sebastian Kobold
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia. Nature biotechnology (2023)
David Andreu-Sanz, Sebastian Kobold
Role and Potential of Different T Helper Cell Subsets in Adoptive Cell Therapy. Cancers 15 (6) (2023)
Theo Lorenzini, Bruno Loureiro Cadilha, Hannah Obeck, Mohamed-Reda Benmebarek, Florian Märkl, Stefanos Michaelides, Thaddäus Strzalkowski, Daria Briukhovetska, Philipp Jie Müller, Sayantan Nandi, Pia Winter, Lina Majed, Ruth Grünmeier, Matthias Seifert, Svenja Rausch, Tobias Feuchtinger, Stefan Endres, Sebastian Kobold
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy. British journal of cancer (2023)
Kristina A M Arendt, Giannoula Ntaliarda, Vasileios Armenis, Danai Kati, Christin Henning, Georgia A Giotopoulou, Mario A A Pepe, Laura V Klotz, Anne-Sophie Lamort, Rudolf A Hatz, Sebastian Kobold, Andrea C Schamberger, Georgios T Stathopoulos
An In Vivo Inflammatory Loop Potentiates KRAS Blockade. Biomedicines 10 (3) (2022)
Lisa Gregor, Sophia Stock, Sebastian Kobold
ESCRT machinery: role of membrane repair mechanisms in escaping cell death. Signal transduction and targeted therapy 7 (1) (2022)
Barbara Spix, Elisabeth S Butz, Cheng-Chang Chen, Anna Scotto Rosato, Rachel Tang, Aicha Jeridi, Veronika Kudrina, Eva Plesch, Philipp Wartenberg, Elisabeth Arlt, Daria Briukhovetska, Meshal Ansari, Gizem Günes Günsel, Thomas M Conlon, Amanda Wyatt, Sandra Wetzel, Daniel Teupser, Lesca M Holdt, Fabien Ectors, Ingrid Boekhoff, Ulrich Boehm, Jaime García-Añoveros, Paul Saftig, Martin A Giera, Sebastian Kobold, Herbert B Schiller, Susanna Zierler, Thomas Gudermann, Christian Wahl-Schott, Franz Bracher, Ali Oender Yildirim, Martin Biel, Christian M Grimm
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice. Nature communications 13 (1) (2022)
Sophia Stock, Anna-Kristina Kluever, Stefan Endres, Sebastian Kobold
Enhanced Chimeric Antigen Receptor T Cell Therapy through Co-Application of Synergistic Combination Partners. Biomedicines 10 (2) (2022)
Duc Huynh, Pia Winter, Florian Märkl, Stefan Endres, Sebastian Kobold
Beyond direct killing-novel cellular immunotherapeutic strategies to reshape the tumor microenvironment. Seminars in immunopathology (2022)
Stefanos Michaelides, Hannah Obeck, Daryna Kechur, Stefan Endres, Sebastian Kobold
Migratory Engineering of T Cells for Cancer Therapy. Vaccines 10 (11) (2022)
Sophia Stock, Mohamed-Reda Benmebarek, Anna-Kristina Kluever, Diana Darowski, Christian Jost, Kay-Gunnar Stubenrauch, Joerg Benz, Anne Freimoser-Grundschober, Ekkehard Moessner, Pablo Umana, Marion Subklewe, Stefan Endres, Christiane Neumann, Sebastian Kobold
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors. Journal for immunotherapy of cancer 10 (7) (2022)
Matthias Seifert, Mohamed-Reda Benmebarek, Daria Briukhovetska, Florian Märkl, Janina Dörr, Bruno L Cadilha, Jakob Jobst, Sophia Stock, David Andreu-Sanz, Theo Lorenzini, Ruth Grünmeier, Arman Oner, Hannah Obeck, Lina Majed, Dario Dhoqina, Manouk Feinendegen, Adrian Gottschlich, Jin Zhang, Ulrike Schindler, Stefan Endres, Sebastian Kobold
Impact of the selective A2 A R and A2 B R dual antagonist AB928/etrumadenant on CAR T cell function. British journal of cancer 127 (12) (2022)
Marcel André Schneider, Laura Heeb, Michal Mateusz Beffinger, Stanislav Pantelyushin, Michael Linecker, Lilian Roth, Kuno Lehmann, Udo Ungethüm, Sebastian Kobold, Rolf Graf, Maries van den Broek, Johannes Vom Berg, Anurag Gupta, Pierre-Alain Clavien
Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models. Science translational medicine 13 (611) (2021)
Daria Briukhovetska, Janina Dörr, Stefan Endres, Peter Libby, Charles A Dinarello, Sebastian Kobold
Interleukins in cancer: from biology to therapy. Nature reviews. Cancer 21 (8) (2021)
Abbass Darwich, Alessandra Silvestri, Mohamed-Reda Benmebarek, Juliette Mouriès, Bruno Cadilha, Alessia Melacarne, Lapo Morelli, Domenico Supino, Alexandre Taleb, Hannah Obeck, Claudio Sustmann, Agnese Losurdo, Giovanna Masci, Giuseppe Curigliano, Sebastian Kobold, Giuseppe Penna, Maria Rescigno
Paralysis of the cytotoxic granule machinery is a new cancer immune evasion mechanism mediated by chitinase 3-like-1. Journal for immunotherapy of cancer 9 (11) (2021)
Julian Kolorz, Salih Demir, Adrian Gottschlich, Iris Beirith, Matthias Ilmer, Daniel Lüthy, Christoph Walz, Mario M Dorostkar, Thomas Magg, Fabian H Hauck, Dietrich von Schweinitz, Sebastian Kobold, Roland Kappler, Michael Berger
The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors. Current oncology (Toronto, Ont.) 29 (1) (2021)
Mohamed-Reda Benmebarek, Bruno L Cadilha, Monika Herrmann, Stefanie Lesch, Saskia Schmitt, Stefan Stoiber, Abbass Darwich, Christian Augsberger, Bettina Brauchle, Lisa Rohrbacher, Arman Oner, Matthias Seifert, Melanie Schwerdtfeger, Adrian Gottschlich, Felicitas Rataj, Nadja C Fenn, Christiane Neumann, Marion Subklewe, Stefan Endres, Karl-Peter Hopfner, Sebastian Kobold
A modular and controllable T cell therapy platform for acute myeloid leukemia. Leukemia 35 (8) (2021)
Stefanie Lesch, Viktoria Blumenberg, Stefan Stoiber, Adrian Gottschlich, Justyna Ogonek, Bruno Loureiro Cadilha, Zahra Dantes, Felicitas Rataj, Klara Dorman, Johannes Lutz, Clara H Karches, Constanze Heise, Mathias Kurzay, Benjamin M Larimer, Simon Grassmann, Moritz Rapp, Alessia Nottebrock, Stephan Kruger, Nicholas Tokarew, Philipp Metzger, Christine Hoerth, Mohamed-Reda Benmebarek, Dario Dhoqina, Ruth Grünmeier, Matthias Seifert, Arman Oener, Öykü Umut, Sandy Joaquina, Lene Vimeux, Thi Tran, Thomas Hank, Taisuke Baba, Duc Huynh, Remco T A Megens, Klaus-Peter Janssen, Martin Jastroch, Daniel Lamp, Svenja Ruehland, Mauro Di Pilato, Jasper N Pruessmann, Moritz Thomas, Carsten Marr, Steffen Ormanns, Anna Reischer, Michael Hristov, Eric Tartour, Emmanuel Donnadieu, Simon Rothenfußer, Peter Duewell, Lars M Koenig, Max Schnurr, Marion Subklewe, Andrew S Liss, Niels Halama, Maximilian Reichert, Thorsten R Mempel, Stefan Endres, Sebastian Kobold
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours. Nature biomedical engineering 5 (11) (2021)
Öykü Umut, Adrian Gottschlich, Stefan Endres, Sebastian Kobold
CAR T cell therapy in solid tumors: a short review. Memo 14 (2) (2021)
Melanie Schwerdtfeger, Mohamed-Reda Benmebarek, Stefan Endres, Marion Subklewe, Vincenzo Desiderio, Sebastian Kobold
Chimeric Antigen Receptor-Modified T Cells and T Cell-Engaging Bispecific Antibodies: Different Tools for the Same Job. Current hematologic malignancy reports 16 (2) (2021)
Bruno Loureiro Cadilha, Mohamed-Reda Benmebarek, Klara Dorman, Arman Oner, Theo Lorenzini, Hannah Obeck, Mira Vänttinen, Mauro Di Pilato, Jasper N Pruessmann, Stefan Stoiber, Duc Huynh, Florian Märkl, Matthias Seifert, Katrin Manske, Javier Suarez-Gosalvez, Yi Zeng, Stefanie Lesch, Clara H Karches, Constanze Heise, Adrian Gottschlich, Moritz Thomas, Carsten Marr, Jin Zhang, Dharmendra Pandey, Tobias Feuchtinger, Marion Subklewe, Thorsten R Mempel, Stefan Endres, Sebastian Kobold
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors. Science advances 7 (24) (2021)
Adrian Gottschlich, Stefan Endres, Sebastian Kobold
Therapeutic Strategies for Targeting IL-1 in Cancer. Cancers 13 (3) (2021)
Ali Bashiri Dezfouli, Mina Yazdi, Alan Graham Pockley, Mohammad Khosravi, Sebastian Kobold, Ernst Wagner, Gabriele Multhoff
NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development. Cells 10 (12) (2021)
Martina Geiger, Kay-Gunnar Stubenrauch, Johannes Sam, Wolfgang F Richter, Gregor Jordan, Jan Eckmann, Carina Hage, Valeria Nicolini, Anne Freimoser-Grundschober, Mirko Ritter, Matthias E Lauer, Henning Stahlberg, Philippe Ringler, Jigar Patel, Eric Sullivan, Sandra Grau-Richards, Stefan Endres, Sebastian Kobold, Pablo Umaña, Peter Brünker, Christiane Neumann
Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody. Nature communications 11 (1) (2020)
Mohamed-Reda Benmebarek, Clara Helke Karches, Bruno Loureiro Cadilha, Stefanie Lesch, Stefan Endres, Sebastian Kobold
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells. International journal of molecular sciences 20 (6) (2019)
Stefan Stoiber, Bruno Loureiro Cadilha, Mohamed-Reda Benmebarek, Stefanie Lesch, Stefan Endres, Sebastian Kobold
Limitations in the Design of Chimeric Antigen Receptors for Cancer Therapy. Cells 8 (5) (2019)
Xiao Liu, Junjian Li, Bruno Loureiro Cadilha, Anamarija Markota, Cornelia Voigt, Zhe Huang, Peter P Lin, Daisy D Wang, Juncheng Dai, Gisela Kranz, Anna Krandick, Darko Libl, Horst Zitzelsberger, Isabella Zagorski, Herbert Braselmann, Min Pan, Sibo Zhu, Yuanchi Huang, Sebastian Niedermeyer, Christoph A Reichel, Bernd Uhl, Daria Briukhovetska, Javier Suárez, Sebastian Kobold, Olivier Gires, Hongxia Wang
Epithelial-type systemic breast carcinoma cells with a restricted mesenchymal transition are a major source of metastasis. Science advances 5 (6) (2019)
Sebastian Kobold
Innate and adaptive immunity combined for cancer treatment. Proceedings of the National Academy of Sciences of the United States of America 116 (4) (2018)
Lucas Ferrari de Andrade, Rong En Tay, Deng Pan, Adrienne M Luoma, Yoshinaga Ito, Soumya Badrinath, Daphne Tsoucas, Bettina Franz, Kenneth F May, Christopher J Harvey, Sebastian Kobold, Jason W Pyrdol, Charles Yoon, Guo-Cheng Yuan, Frank Stephen Hodi, Glenn Dranoff, Kai W Wucherpfennig
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity. Science (New York, N.Y.) 359 (6383) (2018)
Cornelia Voigt, Peter May, Adrian Gottschlich, Anamarija Markota, Daniel Wenk, Inga Gerlach, Sebastian Voigt, Georgios T Stathopoulos, Kristina A M Arendt, Constanze Heise, Felicitas Rataj, Klaus-Peter Janssen, Melanie Königshoff, Hauke Winter, Isabelle Himsl, Wolfgang E Thasler, Max Schnurr, Simon Rothenfußer, Stefan Endres, Sebastian Kobold
Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth. Proceedings of the National Academy of Sciences of the United States of America 114 (49) (2017)