Angelika Eggert

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 30

Top Topics

Stem Cell Transplantation

Papillary Thyroid

Dna Damage Response

Top Venues

Nature genetics

Cancer discovery

Molecular cancer therapeutics

This page only lists publications with an associated author ORCID identifier.

Publications

Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Séverine Kunz, Animesh Bhattacharya, Mara-Camelia Rusu, Dennis Gurgen, Frank P B Dubios, Julia K C Koppke, Jutta Proba, Nadine Wittstruck, Olga Alexandra Sidorova, Rocio Chamorro González, Heathcliff Dorado Garcia, Lotte Brueckner, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Qinghao Yu, Bastiaan Spanjaard, Richard P Koche, Clemens A Schmitt, Johannes Hubertus Schulte, Angelika Eggert, Kerstin Haase, Jennifer A Kirwan, Anja I H Hagemann, Philipp Mertins, Jan R Dorr, Anton G Henssen
Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer. Cancer discovery 14 (3) (2024)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models. Molecular cancer therapeutics 23 (4) (2024)
Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Séverine Kunz, Animesh Bhattacharya, Mara-Camelia Rusu, Dennis Gurgen, Frank P B Dubios, Julia K C Koppke, Jutta Proba, Nadine Wittstruck, Olga Alexandra Sidorova, Rocio Chamorro González, Heathcliff Dorado Garcia, Lotte Brueckner, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Qinghao Yu, Bastiaan Spanjaard, Richard P Koche, Clemens A Schmitt, Johannes Hubertus Schulte, Angelika Eggert, Kerstin Haase, Jennifer A Kirwan, Anja I H Hagemann, Philipp Mertins, Jan R Dorr, Anton G Henssen
Passenger gene co-amplifications create collateral therapeutic vulnerabilities in cancer. Cancer discovery (2024)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models. Molecular cancer therapeutics 23 (4) (2024)
Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Séverine Kunz, Animesh Bhattacharya, Mara-Camelia Rusu, Dennis Gurgen, Frank P B Dubios, Julia K C Koppke, Jutta Proba, Nadine Wittstruck, Olga Alexandra Sidorova, Rocio Chamorro González, Heathcliff Dorado Garcia, Lotte Brueckner, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Qinghao Yu, Bastiaan Spanjaard, Richard P Koche, Clemens A Schmitt, Johannes Hubertus Schulte, Angelika Eggert, Kerstin Haase, Jennifer A Kirwan, Anja I H Hagemann, Philipp Mertins, Jan R Dorr, Anton G Henssen
Passenger gene co-amplifications create collateral therapeutic vulnerabilities in cancer. Cancer discovery (2024)
Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Séverine Kunz, Animesh Bhattacharya, Mara-Camelia Rusu, Dennis Gurgen, Frank P B Dubios, Julia K C Koppke, Jutta Proba, Nadine Wittstruck, Olga Alexandra Sidorova, Rocio Chamorro González, Heathcliff Dorado Garcia, Lotte Brueckner, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Qinghao Yu, Bastiaan Spanjaard, Richard P Koche, Clemens A Schmitt, Johannes Hubertus Schulte, Angelika Eggert, Kerstin Haase, Jennifer A Kirwan, Anja I H Hagemann, Philipp Mertins, Jan R Dorr, Anton G Henssen
Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer. Cancer discovery 14 (3) (2024)
Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Séverine Kunz, Animesh Bhattacharya, Mara-Camelia Rusu, Dennis Gurgen, Frank P B Dubios, Julia K C Koppke, Jutta Proba, Nadine Wittstruck, Olga Alexandra Sidorova, Rocio Chamorro González, Heathcliff Dorado Garcia, Lotte Brueckner, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Qinghao Yu, Bastiaan Spanjaard, Richard P Koche, Clemens A Schmitt, Johannes Hubertus Schulte, Angelika Eggert, Kerstin Haase, Jennifer A Kirwan, Anja I H Hagemann, Philipp Mertins, Jan R Dorr, Anton G Henssen
Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer. Cancer discovery 14 (3) (2024)
Yi Bei, Luca Bramé, Marieluise Kirchner, Raphaela Fritsche-Guenther, Séverine Kunz, Animesh Bhattacharya, Mara-Camelia Rusu, Dennis Gurgen, Frank P B Dubios, Julia K C Koppke, Jutta Proba, Nadine Wittstruck, Olga Alexandra Sidorova, Rocio Chamorro González, Heathcliff Dorado Garcia, Lotte Brueckner, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Qinghao Yu, Bastiaan Spanjaard, Richard P Koche, Clemens A Schmitt, Johannes Hubertus Schulte, Angelika Eggert, Kerstin Haase, Jennifer A Kirwan, Anja I H Hagemann, Philipp Mertins, Jan R Dorr, Anton G Henssen
Passenger Gene Coamplifications Create Collateral Therapeutic Vulnerabilities in Cancer. Cancer discovery 14 (3) (2024)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models. Molecular cancer therapeutics 23 (4) (2024)
Holger N Lode, Ruth Ladenstein, Sascha Troschke-Meurer, Linda Struppe, Nikolai Siebert, Maxi Zumpe, Karoline Ehlert, Stefanie Huber, Evgenia Glogova, Patrick Hundsdoerfer, Angelika Eggert, Anna Zaniewska-Tekieli, Walentyna Balwierz, Aleksandra Wieczorek
Effect and Tolerance of N5 and N6 Chemotherapy Cycles in Combination with Dinutuximab Beta in Relapsed High-Risk Neuroblastoma Patients Who Failed at Least One Second-Line Therapy. Cancers 15 (13) (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics (2023)
Tim Flaadt, Martin Ebinger, Malin Schreiber, Ruth L Ladenstein, Thorsten Simon, Holger N Lode, Barbara Hero, Martin U Schuhmann, Jürgen Frank Schäfer, Frank Paulsen, Beate Timmermann, Angelika Eggert, Peter Lang
Multimodal Therapy with Consolidating Haploidentical Stem Cell Transplantation and Dinutuximab Beta for Patients with High-Risk Neuroblastoma and Central Nervous System Relapse. Journal of clinical medicine 12 (19) (2023)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has anti-tumor activity in preclinical patient-derived pediatric solid tumor models. Molecular cancer therapeutics (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics 55 (5) (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics 55 (5) (2023)
Fabian F Pusch, Heathcliff Dorado Garcia, Robin Xu, Dennis Gurgen, Yi Bei, Lotte Brueckner, Claudia Röefzaad, Jennifer von Stebut, Victor Bardinet, Rocio Chamorro González, Angelika Eggert, Johannes Hubertus Schulte, Patrick Hundsdörfer, Georg Seifert, Kerstin Haase, Beat W Schäfer, Marco Wachtel, Anja A Kühl, Michael V Ortiz, Antje M Wengner, Monika Scheer, Anton G Henssen
Elimusertib has anti-tumor activity in preclinical patient-derived pediatric solid tumor models. Molecular cancer therapeutics (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics 55 (5) (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics 55 (5) (2023)
Steffen Fuchs, Clara Danßmann, Filippos Klironomos, Annika Winkler, Jörg Fallmann, Louisa-Marie Kruetzfeldt, Annabell Krienelke-Szymansky, Julian Naderi, Stephan H Bernhart, Laura Grunewald, Konstantin Helmsauer, Elias Rodriguez-Fos, Marieluise Kirchner, Philipp Mertins, Kathy Astrahantseff, Christin Suenkel, Joern Toedling, Fabienne Meggetto, Marc Remke, Peter F Stadler, Patrick Hundsdoerfer, Hedwig E Deubzer, Annette Künkele, Peter Lang, Jörg Fuchs, Anton G Henssen, Angelika Eggert, Nikolaus Rajewsky, Falk Hertwig, Johannes Hubertus Schulte
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN. Nature communications 14 (1) (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics (2023)
Rocío Chamorro González, Thomas Conrad, Maja C Cwikla, Robin Xu, Madalina Giurgiu, Elias Rodriguez-Fos, Katharina Kasack, Lotte Brueckner, Elias Rodriguez-Fos, Konstantin Helmsauer, Heathcliff Dorado Garcia, Maria E Stefanova, King L Hung, Yi Bei, Karin Schmelz, Marco Lodrini, Stefan Mundlos, Howard Y Chang, Hedwig E Deubzer, Sascha Sauer, Angelika Eggert, Johannes Hubertus Schulte, Roland F Schwarz, Kerstin Haase, Richard P Koche, Anton G Henssen
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells. Nature genetics 55 (5) (2023)
Anne Thorwarth, Kerstin Haase, Claudia Röefzaad, Kristian W Pajtler, Kathrin Schramm, Kathrin Hauptmann, Anke Behnke, Christian Vokuhl, Thomas Elgeti, Alexander Gratopp, Johannes Hubertus Schulte, Monika Scheer, Pablo Hernáiz Driever, Karsten Nysom, Angelika Eggert, Anton G Henssen, Hedwig E Deubzer
Genomic Evolution and Personalized Therapy of an Infantile Fibrosarcoma Harboring an NTRK Oncogenic Fusion. JCO precision oncology 6 (2022)
Marco Lodrini, Jasmin Wünschel, Theresa M Thole-Kliesch, Maddalena Grimaldi, Annika Sprüssel, Rasmus B Linke, Jan F Hollander, Daniela Tiburtius, Annette Künkele, Johannes Hubertus Schulte, Erwin Lankes, Thomas Elgeti, Patrick Hundsdörfer, Kathy Astrahantseff, Thorsten Simon, Angelika Eggert, Hedwig E Deubzer
Circulating Cell-Free DNA Assessment in Biofluids from Children with Neuroblastoma Demonstrates Feasibility and Potential for Minimally Invasive Molecular Diagnostics. Cancers 14 (9) (2022)
Heathcliff Dorado Garcia, Fabian F Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kristina Guillan, Koshi Imami, Dennis Gürgen, Jana Rolff, Konstantin Helmsauer, Stephanie Meyer-Liesener, Natalie Timme, Victor Bardinet, Rocío Chamorro González, Ian C MacArthur, Celine Y Chen, Joachim Schulz, Antje M Wengner, Christian Furth, Birgit Lala, Angelika Eggert, Georg Seifert, Patrick Hundsoerfer, Marieluise Kirchner, Philipp Mertins, Matthias Selbach, Andrej Lissat, Frank Dubois, David Horst, Johannes Hubertus Schulte, Simone Spuler, Daoqi You, Filemon Dela Cruz, Andrew L Kung, Kerstin Haase, Michela Di Virgilio, Monika Scheer, Michael V Ortiz, Anton G Henssen
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma. Nature communications 13 (1) (2022)
Danny Jazmati, Barbara Hero, Theresa M Thole-Kliesch, Julien Merta, Hedwig E Deubzer, Christian Bäumer, Feline Heinzelmann, Stefanie Schulze Schleithoff, Friederike Koerber, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann
Efficacy and Feasibility of Proton Beam Therapy in Relapsed High-Risk Neuroblastoma-Experiences from the Prospective KiProReg Registry. Current oncology (Toronto, Ont.) 29 (11) (2022)
Marco Lodrini, Josefine Graef, Theresa M Thole-Kliesch, Kathy Astrahantseff, Annika Sprüssel, Maddalena Grimaldi, Constantin Peitz, Rasmus B Linke, Jan F Hollander, Erwin Lankes, Annette Künkele, Lena Oevermann, Georg Schwabe, Jörg Fuchs, Annabell Krienelke-Szymansky, Johannes Hubertus Schulte, Patrick Hundsdörfer, Cornelia Eckert, Holger Amthauer, Angelika Eggert, Hedwig E Deubzer
Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (9) (2022)
Ornela Sulejmani, Laura Grunewald, Lena Andersch, Silke Schwiebert, Anika Klaus, Annika Winkler, Kathy Astrahantseff, Angelika Eggert, Anton G Henssen, Johannes Hubertus Schulte, Kathleen Anders, Annette Künkele
Inhibiting Lysine Demethylase 1A Improves L1CAM-Specific CAR T Cell Therapy by Unleashing Antigen-Independent Killing via the FAS-FASL Axis. Cancers 13 (21) (2021)
Karin Schmelz, Joern Toedling, Matthew Huska, Maja C Cwikla, Louisa-Marie Kruetzfeldt, Jutta Proba, Peter F Ambros, Inge M Ambros, Sengül Boral, Marco Lodrini, Celine Y Chen, Martin Burkert, Dennis Guergen, Annabell Krienelke-Szymansky, Kathy Astrahantseff, Annette Kuenkele, Kerstin Haase, Matthias Fischer, Hedwig E Deubzer, Falk Hertwig, Patrick Hundsdoerfer, Anton G Henssen, Roland F Schwarz, Johannes Hubertus Schulte, Angelika Eggert
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions. Nature communications 12 (1) (2021)
Birte Arlt, Guido Mastrobuoni, Jasmin Wuenschel, Kathy Astrahantseff, Angelika Eggert, Stefan Kempa, Hedwig E Deubzer
Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Sandra Ackermann, Maria Cartolano, Barbara Hero, Anne Welte, Yvonne Kahlert, Andrea Roderwieser, Christoph Bartenhagen, Esther Walter, Judith Gecht, Laura Kerschke, Ruth Volland, Roopika Menon, Johannes M Heuckmann, Moritz Gartlgruber, Sabine Hartlieb, Kai-Oliver Henrich, Konstantin Okonechnikov, Janine Altmüller, Peter Nürnberg, Steve Lefever, Bram De Wilde, Frederik Sand, Fakhera Ikram, Carolina Rosswog, Janina Fischer, Jessica Theissen, Falk Hertwig, Aatur D Singhi, Thorsten Simon, Wenzel Vogel, Sven Perner, Barbara Krug, Matthias Schmidt, Sven Rahmann, Viktor Achter, Ulrich Lang, Christian Vokuhl, Monika Ortmann, Reinhard Büttner, Angelika Eggert, Frank Speleman, Roderick J O'Sullivan, Roman K Thomas, Frank Berthold, Jo Vandesompele, Alexander Schramm, Frank Westermann, Johannes H Schulte, Martin Peifer, Matthias Fischer
A mechanistic classification of clinical phenotypes in neuroblastoma. Science (New York, N.Y.) 362 (6419) (2019)