Anthony W Partridge (Anthony Partridge)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 15

Top Venues

Chemical science

Nature communications

Journal of medicinal chemistry

Molecules (Basel, Switzerland)

MSD Translational Medicine Research Centre

This page only lists publications with an associated author ORCID identifier.

Affiliation History

MSD Translational Medicine Research Centre Jul 01 2014

Singapore

Senior Principal Scientist :: Early Discovery Pharmacology

Publications

Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G A Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Shekhar Verma, David P Lane, Tomi K Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J Brown, Charles W Johannes, Anthony W Partridge
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists. Nature communications 15 (1) (2024)
Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G A Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Shekhar Verma, David P Lane, Tomi K Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J Brown, Charles W Johannes, Anthony W Partridge
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists. Nature communications 15 (1) (2024)
Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G A Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Shekhar Verma, David P Lane, Tomi K Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J Brown, Charles W Johannes, Anthony W Partridge
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists. Nature communications 15 (1) (2024)
Stephen H Kasper, Stephanie Otten, Brian Squadroni, Cionna Orr-Terry, Yi Kuang, Lily Mussallem, Lan Ge, Lin Yan, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Christopher J Brown, Charles W Johannes, David Philip Lane, Arun Chandramohan, Anthony W Partridge, Lee R Roberts, Hubert Josien, Alex G Therien, Erik C Hett, Bonnie J Howell, Andrea Peier, Xi Ai, Jason Cassaday
A high-throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell-based assays. Bioengineering & translational medicine 8 (5) (2023)
Michael Garrigou, Bérengère Sauvagnat, Ruchia Duggal, Nicole Boo, Pooja Gopal, Jennifer M Johnston, Anthony W Partridge, Tomi Sawyer, Kaustav Biswas, Nicolas C Boyer
Accelerated Identification of Cell Active KRAS Inhibitory Macrocyclic Peptides using Mixture Libraries and Automated Ligand Identification System (ALIS) Technology. Journal of medicinal chemistry 65 (13) (2022)
Simon Ng, Alexander C Brueckner, Soheila Bahmanjah, Qiaolin Deng, Jennifer M Johnston, Lan Ge, Ruchia Duggal, Bahanu Habulihaz, Benjamin Barlock, Sookhee Ha, Ahmad Sadruddin, Constance Yeo, Corey Strickland, Andrea Peier, Brian Henry, Edward C Sherer, Anthony W Partridge
Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1. Journal of medicinal chemistry (2022)
Shuhui Lim, Nicolas C Boyer, Nicole Boo, Chunhui Huang, Gireedhar Venkatachalam, Yu-Chi Angela Juang, Michael Garrigou, Hung Yi Kristal Kaan, Ruchia Duggal, Khong Ming Peh, Ahmad Sadruddin, Pooja Gopal, Tsz Ying Yuen, Simon Ng, Srinivasaraghavan Kannan, Christopher J Brown, Chandra Shekhar Verma, Peter Orth, Andrea Peier, Lan Ge, Xiang Yu, Bhavana Bhatt, Feifei Chen, Erjia Wang, Nianyu Jason Li, Raymond J Gonzales, Alexander Stoeck, Brian Henry, Tomi K Sawyer, David P Lane, Charles W Johannes, Kaustav Biswas, Anthony W Partridge
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling. Chemical science 12 (48) (2021)
Andrea Peier, Lan Ge, Nicolas Boyer, John Frost, Ruchia Duggal, Kaustav Biswas, Scott Edmondson, Jeffrey D Hermes, Lin Yan, Chad Zimprich, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Christopher J Brown, Dawn Thean, Xue Er Lee, Tsz Ying Yuen, Fernando J Ferrer-Gago, Charles W Johannes, David P Lane, Bradley S Sherborne, Cesear Corona, Matthew B Robers, Tomi K Sawyer, Anthony W Partridge
NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay. ACS chemical biology 16 (2) (2021)
Raphaëlle Berger, Anthony W Partridge
Protein Polymerization as a Novel Targeted Protein Degradation Mechanism. Biochemistry 60 (15) (2021)
Shuhui Lim, Regina Khoo, Khong Ming Peh, Jinkai Teo, Shih Chieh Chang, Simon Ng, Greg L Beilhartz, Roman A Melnyk, Charles W Johannes, Christopher J Brown, David P Lane, Brian Henry, Anthony W Partridge
bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA). Proceedings of the National Academy of Sciences of the United States of America 117 (11) (2020)
Srinivasaraghavan Kannan, Pietro G A Aronica, Simon Ng, Dawn Thean Gek Lian, Yuri Frosi, Sharon Chee, Jiang Shimin, Tsz Ying Yuen, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Jin Huei Wong, Yaw Sing Tan, Zi Wei Chang, Fernando J Ferrer-Gago, Prakash Arumugam, Yi Han, Shiying Chen, Laurent Rénia, Christopher J Brown, Charles W Johannes, Brian Henry, David P Lane, Tomi K Sawyer, Chandra Shekhar Verma, Anthony W Partridge
Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability. Chemical science 11 (21) (2020)
Tsz Ying Yuen, Christopher J Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W Partridge, Chandra Shekhar Verma, David Philip Lane, Charles W Johannes
Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles. Chemical science 10 (26) (2019)
Anthony W Partridge, Hung Yi Kristal Kaan, Yu-Chi Juang, Ahmad Sadruddin, Shuhui Lim, Christopher J Brown, Simon Ng, Dawn Thean, Fernando Ferrer, Charles W Johannes, Tsz Ying Yuen, Srinivasaraghavan Kannan, Pietro G A Aronica, Yaw Sing Tan, Mohan R Pradhan, Chandra S Verma, Jerome Hochman, Shiying Chen, Hui Wan, Sookhee Ha, Brad Sherborne, David P Lane, Tomi K Sawyer
Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties. Molecules (Basel, Switzerland) 24 (12) (2019)
David J Diller, Jon Swanson, Alexander S Bayden, Chris J Brown, Dawn Thean, David P Lane, Anthony W Partridge, Tomi K Sawyer, Joseph Audie
Rigorous Computational and Experimental Investigations on MDM2/MDMX-Targeted Linear and Macrocyclic Peptides. Molecules (Basel, Switzerland) 24 (24) (2019)
Srinivasaraghavan Kannan, Anthony W Partridge, David P Lane, Chandra S Verma
The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors. International journal of molecular sciences 20 (23) (2019)

Anthony W Partridge.css-eqlu8i{font-size:small;padding-left:4px;} (Anthony Partridge)

Publication Activity (10 Years)

Top Topics

Top Venues

Anthony W Partridge (Anthony Partridge)