David Philip Lane (David Lane, David P Lane, D P Lane)

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 18

Top Venues

Scientific reports

Cancer discovery

Proceedings of the National Academy of Sciences of the United States of America

PNAS nexus

Agency for Science Technology and Research

University College London (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Agency for Science Technology and Research

Singapore

Chief Scientist

Education History

University College London

United Kingdom

PHD :: Zoology

University College London Oct 03 1970 - Jun 06 1973

United Kingdom

BSC :: Microbiology

Publications

David Philip Lane
Mutant p53 Gain-of-Function in the Spotlight: Are We Suffering a GOF Delusion? Cancer discovery 14 (2) (2024)
Mihkel Saluri, Axel Leppert, Genis Valentin Gese, Cagla Sahin, Dilraj Lama, Margit Kaldmäe, Gefei Chen, Arne Elofsson, Timothy M Allison, Marie Arsenian Henriksson, Jan Johansson, David Philip Lane, B Martin Hällberg, Michael Landreh
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. PNAS nexus 2 (2) (2023)
David Philip Lane, Chandra Shekhar Verma
Covalent Rescue of Mutant p53. Cancer discovery 13 (1) (2023)
Yuezhen Xue, Boris San Luis, Regine J Dress, Katzrin Binte Ahmad Murad, Florent Ginhoux, Nick Barker, David Philip Lane
Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Stephen H Kasper, Stephanie Otten, Brian Squadroni, Cionna Orr-Terry, Yi Kuang, Lily Mussallem, Lan Ge, Lin Yan, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Christopher J Brown, Charles W Johannes, David Philip Lane, Arun Chandramohan, Anthony W Partridge, Lee R Roberts, Hubert Josien, Alex G Therien, Erik C Hett, Bonnie J Howell, Andrea Peier, Xi Ai, Jason Cassaday
A high-throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell-based assays. Bioengineering & translational medicine 8 (5) (2023)
David Philip Lane, Chandra Shekhar Verma
Covalent Rescue of Mutant p53. Cancer discovery 13 (1) (2023)
Yuezhen Xue, Boris San Luis, Regine J Dress, Katzrin Binte Ahmad Murad, Florent Ginhoux, Nick Barker, David Philip Lane
Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Mihkel Saluri, Axel Leppert, Genis Valentin Gese, Cagla Sahin, Dilraj Lama, Margit Kaldmäe, Gefei Chen, Arne Elofsson, Timothy M Allison, Marie Arsenian Henriksson, Jan Johansson, David Philip Lane, B Martin Hällberg, Michael Landreh
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1. PNAS nexus 2 (2) (2023)
Bibek Bhatta, Ishai Luz, Christian Krueger, Fanny Xueting Teo, David Philip Lane, Kanaga Sabapathy, Tomer Cooks
Cancer Cells Shuttle Extracellular Vesicles Containing Oncogenic Mutant p53 Proteins to the Tumor Microenvironment. Cancers 13 (12) (2021)
Samira Sadeghi, Siddharth Deshpande, Girish Vallerinteavide Mavelli, Mehmet Alphan Aksoyoglu, Jayesh Bafna, Mathias Winterhalter, R Manjunatha Kini, David Philip Lane, Chester Lee Drum
A general approach to protein folding using thermostable exoshells. Nature communications 12 (1) (2021)
Li Ren Kong, Richard Weijie Ong, Tuan-Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, Miyoung Lee, Srinivasaraghavan Kannan, Chandra S Verma, Chwee Ming Lim, Wee Joo Chng, David Philip Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation. Nature communications 11 (1) (2020)
Tsz Ying Yuen, Christopher J Brown, Yuezhen Xue, Yaw Sing Tan, Fernando J Ferrer Gago, Xue Er Lee, Jin Yong Neo, Dawn Thean, Hung Yi Kristal Kaan, Anthony W Partridge, Chandra Shekhar Verma, David Philip Lane, Charles W Johannes
Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles. Chemical science 10 (26) (2019)
Arumay Pal, Kurt Neo, Lakshminarayanan Rajamani, Fernando Jose Ferrer, David Philip Lane, Chandra S Verma, Alessandra Mortellaro
Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides. Scientific reports 9 (1) (2019)
Xin Yu Koh, Xiao Hui Koh, Le-Ann Hwang, Fernando Jose Ferrer, Siti Aishah Binte Rahmat, Dilraj Lama, David Philip Lane
Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase. Oncogene 38 (48) (2019)
Wai-Heng Lua, Wei-Li Ling, Joshua Yi Yeo, Jun-Jie Poh, David Philip Lane, Samuel Ken-En Gan
The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding. Scientific reports 8 (1) (2018)
Wai-Heng Lua, Wei-Li Ling, Joshua Yi Yeo, Jun-Jie Poh, David Philip Lane, Samuel Ken-En Gan
Author Correction: The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding. Scientific reports 8 (1) (2018)
D Thean, J S Ebo, T Luxton, Xue'Er Cheryl Lee, T Y Yuen, F J Ferrer, C W Johannes, David Philip Lane, C J Brown
Enhancing Specific Disruption of Intracellular Protein Complexes by Hydrocarbon Stapled Peptides Using Lipid Based Delivery. Scientific reports 7 (1) (2017)
Shilpa Yadahalli, Jianguo Li, David Philip Lane, Shachi Gosavi, Chandra S Verma
Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulations. Scientific reports 7 (1) (2017)
Wai-Heng Lua, Samuel Ken-En Gan, David Philip Lane, Chandra Shekhar Verma
A search for synergy in the binding kinetics of Trastuzumab and Pertuzumab whole and F(ab) to Her2. NPJ breast cancer 1 (2015)

David Philip Lane.css-eqlu8i{font-size:small;padding-left:4px;} (David Lane, David P Lane, D P Lane)

Publication Activity (10 Years)

Top Topics

Top Venues

David Philip Lane (David Lane, David P Lane, D P Lane)