Srinivasaraghavan Kannan (Kannan Srinivasaraghavan)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 30

Top Venues

Nature communications

Science signaling

Genome medicine

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G A Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Shekhar Verma, David P Lane, Tomi K Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J Brown, Charles W Johannes, Anthony W Partridge
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists. Nature communications 15 (1) (2024)
Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G A Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Shekhar Verma, David P Lane, Tomi K Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J Brown, Charles W Johannes, Anthony W Partridge
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists. Nature communications 15 (1) (2024)
Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S Verma, Yvonne Tay, Daniel Shao-Weng Tan, Wai Leong Tam
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression. Genome medicine 16 (1) (2024)
Tharindunee Jayakody, Asuka Inoue, Srinivasaraghavan Kannan, Gaku Nakamura, Kouki Kawakami, Krishan Mendis, Thanh-Binh Nguyen, Jianguo Li, Deron Raymond Herr, Chandra Shekhar Verma, Gavin Stewart Dawe
Mechanisms of biased agonism by Gα i/o -biased stapled peptide agonists of the relaxin-3 receptor. Science signaling 17 (823) (2024)
Tharindunee Jayakody, Asuka Inoue, Srinivasaraghavan Kannan, Gaku Nakamura, Kouki Kawakami, Krishan Mendis, Thanh-Binh Nguyen, Jianguo Li, Deron Raymond Herr, Chandra Shekhar Verma, Gavin Stewart Dawe
Mechanisms of biased agonism by Gα i/o -biased stapled peptide agonists of the relaxin-3 receptor. Science signaling 17 (823) (2024)
Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S Verma, Yvonne Tay, Daniel Shao-Weng Tan, Wai Leong Tam
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression. Genome medicine 16 (1) (2024)
Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G A Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra Shekhar Verma, David P Lane, Tomi K Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J Brown, Charles W Johannes, Anthony W Partridge
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists. Nature communications 15 (1) (2024)
Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S Verma, Yvonne Tay, Daniel Shao-Weng Tan, Wai Leong Tam
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression. Genome medicine 16 (1) (2024)
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Hy Lum, Wai Kit Cheong, Khay-Guan Yeoh, Ker Kan Tan, Radoslaw Mikolaj Sobota, Chandra S Verma, David P Lane, Wai Leong Tam, Ashok R Venkitaraman
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nature communications 14 (1) (2023)
You Heng Chuah, Emmy Xue Yun Tay, Oleg V Grinchuk, Jeehyun Yoon, Jia Feng, Srinivasaraghavan Kannan, Matius Robert, Rekha Jakhar, Yajing Liang, Bernice Woon Li Lee, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Guang Lu, Boon Chuan Low, Karen Carmelina Crasta, Chandra Shekhar Verma, Zhewang Lin, Derrick Sek Tong Ong
CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma. Cell death and differentiation (2023)
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Hy Lum, Wai Kit Cheong, Khay-Guan Yeoh, Ker Kan Tan, Radoslaw Mikolaj Sobota, Chandra S Verma, David P Lane, Wai Leong Tam, Ashok R Venkitaraman
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Jia Tong Loh, Joey Kay Hui Teo, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Anand Kumar Andiappan, Hong-Hwa Lim, Kong Peng Lam
DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11. Science signaling 16 (809) (2023)
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Hy Lum, Wai Kit Cheong, Khay-Guan Yeoh, Ker Kan Tan, Radoslaw Mikolaj Sobota, Chandra S Verma, David P Lane, Wai Leong Tam, Ashok R Venkitaraman
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Clare Jelinska, Srinivasaraghavan Kannan, Yuri Frosi, Siti Radhiah Ramlan, Fernaldo Winnerdy, Lakshminarayanan Rajamani, Charles W Johannes, Christopher J Brown, Anh-Tuan Phan, Daniela Rhodes, Chandra Shekhar Verma
Stitched peptides as potential cell permeable inhibitors of oncogenic DAXX protein. RSC chemical biology 4 (12) (2023)
Sonia T Nicolaou, Srinivasaraghavan Kannan, Jim Warwicker, Chandra Shekhar Verma
Activation of p53: How phosphorylated Ser15 triggers sequential phosphorylation of p53 at Thr18 by CK1δ. Proteins 90 (12) (2022)
Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Nuria Lopez-Bigas, Mafalda Oliveira, Fara Brasó-Maristany, Nusaibah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, Maria Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández-Losa, Faye Su, Kui Lin, Robert B Clarke, Carlos Caldas, Joaquín Arribas, Stefan Michiels, Alicia García-Sanz, Nicholas C Turner, Aleix Prat, Paolo G Nuciforo, Rodrigo Dienstmann, Chandra S Verma, Núria López-Bigas, Maurizio Scaltriti, Monica Arnedos, Cristina Saura, Violeta Serra
Author Correction: High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER + breast cancer. Nature communications 13 (1) (2022)
Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Nuria Lopez-Bigas, Mafalda Oliveira, Fara Brasó-Maristany, Nusaibah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, Maria Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández-Losa, Faye Su, Kui Lin, Robert B Clarke, Carlos Caldas, Joaquín Arribas, Stefan Michiels, Alicia García-Sanz, Nicholas C Turner, Aleix Prat, Paolo G Nuciforo, Rodrigo Dienstmann, Chandra S Verma, Núria López-Bigas, Maurizio Scaltriti, Monica Arnedos, Cristina Saura, Violeta Serra
High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER + breast cancer. Nature communications 13 (1) (2022)
Shuhui Lim, Nicolas C Boyer, Nicole Boo, Chunhui Huang, Gireedhar Venkatachalam, Yu-Chi Angela Juang, Michael Garrigou, Hung Yi Kristal Kaan, Ruchia Duggal, Khong Ming Peh, Ahmad Sadruddin, Pooja Gopal, Tsz Ying Yuen, Simon Ng, Srinivasaraghavan Kannan, Christopher J Brown, Chandra Shekhar Verma, Peter Orth, Andrea Peier, Lan Ge, Xiang Yu, Bhavana Bhatt, Feifei Chen, Erjia Wang, Nianyu Jason Li, Raymond J Gonzales, Alexander Stoeck, Brian Henry, Tomi K Sawyer, David P Lane, Charles W Johannes, Kaustav Biswas, Anthony W Partridge
Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling. Chemical science 12 (48) (2021)
Weijun Xu, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Kassoum Nacro
Update on the Development of MNK Inhibitors as Therapeutic Agents. Journal of medicinal chemistry (2021)
Li Ren Kong, Richard Weijie Ong, Tuan-Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, Miyoung Lee, Srinivasaraghavan Kannan, Chandra S Verma, Chwee Ming Lim, Wee Joo Chng, David Philip Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation. Nature communications 11 (1) (2020)
Srinivasaraghavan Kannan, Pietro G A Aronica, Simon Ng, Dawn Thean Gek Lian, Yuri Frosi, Sharon Chee, Jiang Shimin, Tsz Ying Yuen, Ahmad Sadruddin, Hung Yi Kristal Kaan, Arun Chandramohan, Jin Huei Wong, Yaw Sing Tan, Zi Wei Chang, Fernando J Ferrer-Gago, Prakash Arumugam, Yi Han, Shiying Chen, Laurent Rénia, Christopher J Brown, Charles W Johannes, Brian Henry, David P Lane, Tomi K Sawyer, Chandra Shekhar Verma, Anthony W Partridge
Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability. Chemical science 11 (21) (2020)
Li Ren Kong, Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Tuan-Zea Tan, Nicholas Li-Xun Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S W Tan, N Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S J Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H Phillip Koeffler, Soo Chin Lee, Dennis Kappei, Huynh The Hung, Boon Cher Goh
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma. Nature communications 11 (1) (2020)
Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M Schram, Helen H Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristorena, Srushti Kittane, Fan Wu, Yanyan Cai, Sabrina Arena, Benedetta Mussolin, Neil Vasan, Alexander N Gorelick, Michael F Berger, Ofra Novoplansky, Sankar Jagadeeshan, Yi Liao, Uwe Rix, Sandra Misale, Barry S Taylor, Alberto Bardelli, Jaclyn F Hechtman, David M Hyman, Moshe Elkabets, Elisa de Stanchina, Chandra S Verma, Andrea Ventura, Alexander E Drilon, Maurizio Scaltriti
TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors. Cancer discovery 11 (1) (2020)
Mohan R Pradhan, Minh N Nguyen, Srinivasaraghavan Kannan, Stephen J Fox, Chee Keong Kwoh, David P Lane, Chandra Shekhar Verma
Characterization of Hydration Properties in Structural Ensembles of Biomolecules. Journal of chemical information and modeling 59 (7) (2019)
Mahalakshmi Harish, Srinivasaraghavan Kannan, Srivalli Puttagunta, Mohan R Pradhan, Chandra Shekhar Verma, Prasanna Venkatraman
A Novel Determinant of PSMD9 PDZ Binding Guides the Evolution of the First Generation of Super Binding Peptides. Biochemistry 58 (32) (2019)
Srinivasaraghavan Kannan, Stephen J Fox, Chandra Shekhar Verma
Exploring Gatekeeper Mutations in EGFR through Computer Simulations. Journal of chemical information and modeling 59 (6) (2019)
Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket. Chemical science 9 (23) (2018)
Srinivasaraghavan Kannan, Daniel Shao-Weng Tan, Chandra Shekhar Verma
Effects of Single Nucleotide Polymorphisms on the Binding of Afatinib to EGFR: A Potential Patient Stratification Factor Revealed by Modeling Studies. Journal of chemical information and modeling 59 (1) (2018)
Yee Hwa Wong, Akshita Kumar, Chong Wai Liew, Kannan Tharakaraman, Srinivasaraghavan Kannan, Ram Sasisekharan, Chandra Verma, Julien Lescar
Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513. Scientific reports 8 (1) (2018)
Haiyan Yang, Lohitha Rao Chennamaneni, Melvyn Wai Tuck Ho, Shi Hua Ang, Eldwin Sum Wai Tan, Duraiswamy Athisayamani Jeyaraj, Yoon Sheng Yeap, Boping Liu, Esther Hq Ong, Joma Kanikadu Joy, John Liang Kuan Wee, Perlyn Kwek, Priya Retna, Nurul Dinie, Thuy Thi Hanh Nguyen, Shi Jing Tai, Vithya Manoharan, Vishal Pendharkar, Choon Bing Low, Yun Shan Chew, Susmitha Vuddagiri, Kanda Sangthongpitag, Meng Ling Choong, May Ann Lee, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Anders Poulsen, Sharon Lim, Charles Chuah, Tiong Sin Ong, Jeffrey Hill, Alex Matter, Kassoum Nacro
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia. Journal of medicinal chemistry 61 (10) (2018)

Srinivasaraghavan Kannan.css-eqlu8i{font-size:small;padding-left:4px;} (Kannan Srinivasaraghavan)

Publication Activity (10 Years)

Top Topics

Top Venues

Srinivasaraghavan Kannan (Kannan Srinivasaraghavan)