Arun Radhakrishnan

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Venues

eLife

Proceedings of the National Academy of Sciences of the United States of America

The Journal of biological chemistry

Nature chemical biology

University of Texas Southwestern Medical Center at Dallas

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Texas Southwestern Medical Center at Dallas

United States

Associate Professor :: Molecular Genetics

Publications

Shimeng Xu, Jared C Smothers, Daphne Rye, Shreya Endapally, Hong Chen, Shili Li, Guosheng Liang, Maia Kinnebrew, Rajat Rohatgi, Bruce A Posner, Arun Radhakrishnan
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Shimeng Xu, Jared C Smothers, Daphne Rye, Shreya Endapally, Hong Chen, Shili Li, Guosheng Liang, Maia Kinnebrew, Rajat Rohatgi, Bruce A Posner, Arun Radhakrishnan
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Shimeng Xu, Jared C Smothers, Daphne Rye, Shreya Endapally, Hong Chen, Shili Li, Guosheng Liang, Maia Kinnebrew, Rajat Rohatgi, Bruce A Posner, Arun Radhakrishnan
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Shimeng Xu, Jared C Smothers, Daphne Rye, Shreya Endapally, Hong Chen, Shili Li, Guosheng Liang, Maia Kinnebrew, Rajat Rohatgi, Bruce A Posner, Arun Radhakrishnan
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Shimeng Xu, Jared C Smothers, Daphne Rye, Shreya Endapally, Hong Chen, Shili Li, Guosheng Liang, Maia Kinnebrew, Rajat Rohatgi, Bruce A Posner, Arun Radhakrishnan
A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
David B Heisler, Kristen A Johnson, Duo H Ma, Maikke B Ohlson, Lishu Zhang, Michelle Tran, Chase D Corley, Michael E Abrams, Jeffrey G McDonald, John W Schoggins, Neal M Alto, Arun Radhakrishnan
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection. eLife 12 (2023)
David B Heisler, Kristen A Johnson, Duo H Ma, Maikke B Ohlson, Lishu Zhang, Michelle Tran, Chase D Corley, Michael E Abrams, Jeffrey G McDonald, John W Schoggins, Neal M Alto, Arun Radhakrishnan
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection. eLife 12 (2023)
David B Heisler, Kristen A Johnson, Duo H Ma, Maikke B Ohlson, Lishu Zhang, Michelle Tran, Chase D Corley, Michael E Abrams, Jeffrey G McDonald, John W Schoggins, Neal M Alto, Arun Radhakrishnan
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection. eLife 12 (2023)
David B Heisler, Kristen A Johnson, Duo H Ma, Maikke B Ohlson, Lishu Zhang, Michelle Tran, Chase D Corley, Michael E Abrams, Jeffrey G McDonald, John W Schoggins, Neal M Alto, Arun Radhakrishnan
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection. eLife 12 (2023)
David B Heisler, Kristen A Johnson, Duo H Ma, Maikke B Ohlson, Lishu Zhang, Michelle Tran, Chase D Corley, Michael E Abrams, Jeffrey G McDonald, John W Schoggins, Neal M Alto, Arun Radhakrishnan
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection. eLife 12 (2023)
David B Heisler, Kristen A Johnson, Duo H Ma, Maikke B Ohlson, Lishu Zhang, Michelle Tran, Chase D Corley, Michael E Abrams, Jeffrey G McDonald, John W Schoggins, Neal M Alto, Arun Radhakrishnan
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection. eLife 12 (2023)
Maia Kinnebrew, Giovanni Luchetti, Ria Sircar, Sara Frigui, Lucrezia Vittoria Viti, Tomoki Naito, Francis Beckert, Yasunori Saheki, Christian Siebold, Arun Radhakrishnan, Rajat Rohatgi
Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes. eLife 10 (2021)
Arun Radhakrishnan, Rajat Rohatgi, Christian Siebold
Cholesterol access in cellular membranes controls Hedgehog signaling. Nature chemical biology 16 (12) (2020)
Daniel L Kober, Shimeng Xu, Shili Li, Bilkish Bajaj, Guosheng Liang, Daniel M Rosenbaum, Arun Radhakrishnan
Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis. Proceedings of the National Academy of Sciences of the United States of America 117 (45) (2020)
Michael E Abrams, Kristen A Johnson, Sofya S Perelman, Li-Shu Zhang, Shreya Endapally, Katrina B Mar, Bonne M Thompson, Jeffrey G McDonald, John W Schoggins, Arun Radhakrishnan, Neal M Alto
Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol. Nature microbiology 5 (7) (2020)
Kristen A Johnson, Arun Radhakrishnan
Accessibility of cholesterol at cell surfaces. Journal of lipid research 61 (10) (2020)
Maia Kinnebrew, Ellen J Iverson, Bhaven B Patel, Ganesh V Pusapati, Jennifer H Kong, Kristen A Johnson, Giovanni Luchetti, Kaitlyn M Eckert, Jeffrey G McDonald, Douglas F Covey, Christian Siebold, Arun Radhakrishnan, Rajat Rohatgi
Cholesterol accessibility at the ciliary membrane controls hedgehog signaling. eLife 8 (2019)
Kristen A Johnson, Shreya Endapally, Danya C Vazquez, Rodney E Infante, Arun Radhakrishnan
Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum. The Journal of biological chemistry 294 (46) (2019)
Rima S Chakrabarti, Sally A Ingham, Julia Kozlitina, Austin Gay, Jonathan C Cohen, Arun Radhakrishnan, Helen H Hobbs
Variability of cholesterol accessibility in human red blood cells measured using a bacterial cholesterol-binding toxin. eLife 6 (2017)
Rodney Elwood Infante, Arun Radhakrishnan
Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol. eLife 6 (2017)

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Publication Activity (10 Years)

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Arun Radhakrishnan