Betty Kim Lee Sim (B Kim Lee Sim)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 15

Top Topics

Monoclonal Antibody

Gene Expression

Plasmodium Falciparum

Top Venues

EMBO molecular medicine

Nature medicine

Science translational medicine

Journal of immunology (Baltimore, Md. : 1950)

This page only lists publications with an associated author ORCID identifier.

Publications

Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, Betty Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan H I Kappe
A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion. EMBO molecular medicine 16 (4) (2024)
Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, Betty Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan H I Kappe
A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion. EMBO molecular medicine 16 (4) (2024)
Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, Betty Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan H I Kappe
A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion. EMBO molecular medicine (2024)
Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, Betty Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan H I Kappe
A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion. EMBO molecular medicine 16 (4) (2024)
Debashree Goswami, Hardik Patel, William Betz, Janna Armstrong, Nelly Camargo, Asha Patil, Sumana Chakravarty, Sean C Murphy, Betty Kim Lee Sim, Ashley M Vaughan, Stephen L Hoffman, Stefan H I Kappe
A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion. EMBO molecular medicine 16 (4) (2024)
Sodiomon Bienvenu Sirima, Alphonse Ouédraogo, Alfred B Tiono, Jean Moise Tanga Kaboré, Edith C Bougouma, Maurice S Ouattara, Désiré Kargougou, Amidou Diarra, Noelie Henry, Issa N Ouédraogo, Chmi-Sika Study Team, Anita Manoj, Yonas Abebe, Natasha Kc, Adam Ruben, Thomas L Richie, Eric R James, Sudhaunshu Joshi, Biraj Shrestha, Kathy Strauss, Kirsten E Lyke, Christopher V Plowe, Gail E Potter, Catherine Cox, Walter Jones, Betty Kim Lee Sim, Stephen L Hoffman, Matthew B Laurens
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria. Science translational medicine 14 (674) (2022)
Ilka Bartsch, Anna S Obraztsova, Julia Puchan, Rebecca Hundsdorfer, Sumana Chakravarty, Betty Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Hedda Wardemann
Clonal evolution and TCR specificity of the human T FH cell response to Plasmodium falciparum CSP. Science immunology 7 (72) (2022)
Meta Roestenberg, Jona Walk, Saskia C van der Boor, Marijke C C Langenberg, Marie-Astrid Hoogerwerf, Jacqueline J Janse, Mikhael Manurung, X Zen Yap, Amanda Fabra García, Jan Pieter R Koopman, Pauline Meij, Els Wessels, Karina Teelen, Youri M van Waardenburg, Marga van de Vegte-Bolmer, Geert Jan van Gemert, Leo G Visser, André J A M van der Ven, Quirijn de Mast, K C Natasha, Yonas Abebe, Tooba Murshedkar, Thomas L Richie, Betty Kim Lee Sim, Chris J Janse, Stephen L Hoffman, Shahid M Khan, Robert W Sauerwein
A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1. Science translational medicine 12 (544) (2021)
Anna Bachmann, Ellen Bruske, Ralf Krumkamp, Louise Turner, Jan Stephan Wichers-Misterek, Michaela Petter, Jana Held, Michael F Duffy, Betty Kim Lee Sim, Stephen L Hoffman, Peter G Kremsner, Bertrand Lell, Thomas Lavstsen, Matthias Frank, Benjamin Mordmüller, Egbert Tannich
Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression. PLoS pathogens 15 (7) (2019)
Tobias Rutishauser, Marco Lepore, Daniela Di Blasi, Jean-Pierre Dangy, Salim Abdulla, Said Jongo, Kamaka Ramadhani, Betty Kim Lee Sim, Stephen L Hoffman, Marcel Tanner, Claudia A Daubenberger, Gennaro De Libero
Activation of TCR Vδ1+ and Vδ1-Vδ2- γδ T Cells upon Controlled Infection with Plasmodium falciparum in Tanzanian Volunteers. Journal of immunology (Baltimore, Md. : 1950) 204 (1) (2019)
Rajagopal Murugan, Lisa Buchauer, Gianna Triller, Cornelia Kreschel, Giulia Costa, Gemma Pidelaserra Martí, Katharina Imkeller, Christian E Busse, Sumana Chakravarty, Betty Kim Lee Sim, Stephen L Hoffman, Elena A Levashina, Peter G Kremsner, Benjamin Mordmüller, Thomas Höfer, Hedda Wardemann
Clonal selection drives protective memory B cell responses in controlled human malaria infection. Science immunology 3 (20) (2018)
Joshua Tan, Brandon K Sack, David Oyen, Isabelle Zenklusen, Luca Piccoli, Sonia Barbieri, Mathilde Foglierini, Chiara Silacci Fregni, Jessica Marcandalli, Said Jongo, Salim Abdulla, Laurent Perez, Giampietro Corradin, Luca Varani, Federica Sallusto, Betty Kim Lee Sim, Stephen L Hoffman, Stefan H I Kappe, Claudia A Daubenberger, Ian A Wilson, Antonio Lanzavecchia
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. Nature medicine 24 (4) (2018)
Katharina Imkeller, Stephen W Scally, Alexandre Bosch, Gemma Pidelaserra Martí, Giulia Costa, Gianna Triller, Rajagopal Murugan, Valerio Renna, Hassan Jumaa, Peter G Kremsner, Betty Kim Lee Sim, Stephen L Hoffman, Benjamin Mordmüller, Elena A Levashina, Jean-Philippe Julien, Hedda Wardemann
Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science (New York, N.Y.) 360 (6395) (2018)
Neville K Kisalu, Azza H Idris, Connor Weidle, Yevel Flores-Garcia, Barbara J Flynn, Brandon K Sack, Sean Murphy, Arne Schön, Ernesto Freire, Joseph R Francica, Alex B Miller, Jason Gregory, Sandra March, Hua-Xin Liao, Barton F Haynes, Kevin Wiehe, Ashley M Trama, Kevin O Saunders, Morgan A Gladden, Anthony Monroe, Mattia Bonsignori, Masaru Kanekiyo, Adam K Wheatley, Adrian B McDermott, S Katie Farney, Gwo-Yu Chuang, Baoshan Zhang, Natasha Kc, Sumana Chakravarty, Peter D Kwong, Photini Sinnis, Sangeeta N Bhatia, Stefan H I Kappe, Betty Kim Lee Sim, Stephen L Hoffman, Fidel Zavala, Marie Pancera, Robert A Seder
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature medicine 24 (4) (2018)
Irfan Zaidi, Hama Diallo, Solomon Conteh, Yvette Robbins, Jacqueline Kolasny, Sachy Orr-Gonzalez, Dariyen Carter, Brandi Butler, Lynn Lambert, Elizabeth Brickley, Robert Morrison, Mahamadou Sissoko, Sara Anne Healy, Betty Kim Lee Sim, Ogobara K Doumbo, Stephen L Hoffman, Patrick E Duffy
γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations. Journal of immunology (Baltimore, Md. : 1950) 199 (11) (2017)